CAS: 123-63-7; Paraldehyde

上下游产品

CAS号75-07-0 乙醛 | CAS号917-92-0 3,3-二甲基-1-丁炔 | CAS号109-63-7 三氟化硼乙醚 | CAS号142-45-0 丁炔二酸 | CAS号624-85-1 ethyl hyp°Chlorite | CAS号122-51-0 原甲酸三乙酯 | CAS号1115-15-7 1-ethenylsulfin... | CAS号105-57-7 1,1-二乙氧基乙烷 | CAS号534-15-6 乙缩醛二甲醇 | CAS号64-17-5 乙醇 | CAS号4130-42-1 2,6-二叔丁基-4-乙基苯酚 | CAS号718624-10-3 1,3-bis(3,5-di-... | CAS号96-76-4 2,4-二叔丁基酚 | CAS号100669-72-5 3-(3,5-di-tert-... | CAS号536-78-7 3-乙基吡啶 | CAS号108-99-6 3-甲基吡啶 | CAS号104-90-5 2-甲基-5-乙基吡啶 | CAS号589-93-5 2,5-二甲基吡啶 | CAS号534-15-6 乙缩醛二甲醇 | CAS号497-26-7 2-甲基-1,3-二氧戊环

Ethyl Hypochlorite置于乙醇体系中,化学反应生成三聚乙醛
参考文献:Chattaway; Backeberg,Journal Of The Chemical Society,1924,Vol. 125,P. 1099
标题:Chattaway; Backeberg,Journal Of The Chemical Society,1924,Vol. 125,P. 1099

专利信息

专利号:WO-2016056031-A1
优先权日:2014-10-08
标题:Novel diol compounds synthesis and its use for formal synthesis of (2r, 3 s)-3-hydroxypipecolic acid
发明人：CHAVAN SUBHASH PRATAPRAO; PAWAR KAILASH PRALHAD
权利人:COUNCIL SCIENT IND RES
摘要:The patent discloses novel diol derivatives of general formula I, [Formula should be inserted here] A chiral pool process for the synthesis of the compound of formula I from D glucose. Further, it discloses a process for the synthesis of (2 R , 3 S )-3-hydroxypipecolic acid from D- glucose using chiral pool approach, wherein the D-glucose used is in enantiomerically pure form.

专利号:US-4592874-A
优先权日:1980-05-14
标 题:Process for the synthesis of alpha-chlorinated chloroformates
发明人：CAGNON GUY C; PITEAU MARC D; SENET JEAN-PIERRE G; OLOFSON ROY A; MARTZ JONATHAN T
权利人:POUDRES & EXPLOSIFS STE NALE
摘要:Process for the synthesis of alpha -chlorinated chloroformates, and new alpha -chlorinated chloroformates. The invention relates to a new process for the manufacture of alpha -chlorinated chloroformates and, to new alpha -chlorinated chloroformates as new industrial products. The process according to the invention consists of a synthesis, by catalytic phosgenation, of alpha -chlorinated chloroformates of the formula: in which: R represents a substituted or unsubstituted hydrocarbon radical and m represents an integer superior or equal to one, this synthesis consisting in reacting phosgene with the aldehyde R-CHO)m, in the presence of a catalyst which is an organic or inorganic substance which is capable in a medium containing an aldehyde of the formula R-CHO)m, phosgene and, possibly, a solvent, of generating a pair of ions one of which is an halogenide anion and the other is a cation which is sufficiently separated from said halogenide anion so as to give to the latter a nucleophilic power enabling it to react with the function(s) aldehyde of the molecule R-CHO)m.

专利号:EP-3263552-A1
优先权日:2016-06-28
标 题:Methods for preparing intermediates for the synthesis of obeticholic acid
发明人：KUBELKA TOMAS; SLAVIKOVA MARKETA; ZEZULA JOSEF; CERNY JOSEF
权利人:ZENTIVA KS
摘要:The present invention discloses a method for preparing the key intermediates of formula 2 (disilylated derivative) and enones of formula 3 (mixture of E/Z isomers) for synthesis of the active pharmaceutical ingredient - obeticholic acid of formula 1. The principle of the method is that it comprises a reaction of the compound of formula 8 , wherein R 1 is a C1 to C4 linear or branched alkyl, with trimethylsilyl iodide in the presence of a base and a mixture of a polar aprotic and non-polar solvent under an inert atmosphere at a temperature in the range of from 40°C to 70°C.

专利号:US-9701634-B2
优先权日:2009-06-24
标 题 :Process for the synthesis of 3-methyl-pyridine
发明人：ROEDERER DETLEF; ZOLLINGER DANIEL; DE RIEDMATTEN JEAN-YVES
权利人:ROEDERER DETLEF; ZOLLINGER DANIEL; DE RIEDMATTEN JEAN-YVES; LONZA AG
摘要:The present invention discloses a process for the synthesis of 3-methyl-pyridine from formaldehyde, paracetaldehyde, ammonia and acetic acid, whereby said compounds are reacted and said process comprises the following parameters:n a) a reaction temperature of 260-300° C.; b) a molar ratio of formaldehyde and paraldehyde (calculated as acetaldehyde) of 0.7-1.4 mol/mol: c) an ammonia concentration of 10-20 weight-% d) an acetic acid concentration of 4-20 weight-% e) a paraldehyde (calculated as acetaldehyde) concentration of 0.4-1.6 Mol/kg f) a retention time of 10-30 minutes in case of a continuous reaction and 10-90 minutes in case of a discontinuous reaction; and g) a reaction pressure of 30-130 bar.

专利号:US-10717718-B2
优先权日:2015-11-17
标 题:5-azido-5-deoxy-2 :3-isopropylidene-D-arabinose compounds; their method of manufacture and their use for the synthesis of ARA-N3, KDO-N3 and 4EKDO-N3
发明人：VAUZEILLES BORIS; MAS PONS JORDI; BARON AURÈLIE
权利人:CENTRE NAT RECH SCIENT
摘要:Disclosed are new compounds of formulae: n nWherein: R 1 and R 2 can be independently H; a C 1 to C 6 alkyl including methyl, ethyl, propyl, butyl; aryl including phenyl, para-methoxyphenyl; or R 1 ,R 2 together with the carbon C-6 can be a cyclopentylidene or cyclohexylidene; each of these groups being substituted or not; and R 3 can be a C 1 to C 6 alkyl including methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, pentyl; or aryl including phenyl, methylphenyl, ethylphenyl, each of these groups being substituted or not. The invention also relates to their method of manufacture and their use for the synthesis of Ara-N 3 , Kdo-N 3 and 4eKdo-N 3 .

专利号:US-8309716-B2
优先权日:2005-07-29
标题 :Pyrrolo[2,3-d]pyrimidine derivatives: their intermediates and synthesis
发明人：RUGGERI SALLY GUT; HAWKINS JOEL M; MAKOWSKI TERESA M; RUTHERFORD JENNIFER L; URBAN FRANK J
权利人:RUGGERI SALLY GUT; HAWKINS JOEL M; MAKOWSKI TERESA M; RUTHERFORD JENNIFER L; URBAN FRANK J; PFIZER
摘要:This invention relates to methods and intermediates useful for the synthesis of pyrrolo[2,3-d]pyrimidine compounds. Specifically novel synthetic methods and intermediates for the synthesis of 3-{(3R,4R)-4-methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino}-piperidin-1-yl)-3-oxo-propionitrile and its corresponding citrate salt are disclosed.