CAS: 31410-01-2; 1-Allyl-1H-Imidazole

相似化合物

65039-10-3 31410-07-8 98873-55-3

咪唑 以40%的收率获得产物
参考文献:Fan Liren,Zhou Yu,Wang Yanggong,Liu Aippin,Lizi Jiaowan Yu Xifu (Ion Exch. And Absorp),9 (1993) N 6,S 529-531
标题:Fan Liren,Zhou Yu,Wang Yanggong,Liu Aippin,Lizi Jiaowan Yu Xifu (Ion Exch. And Absorp),9 (1993) N 6,S 529-531

专利信息

专利号:US-7344863-B2
优先权日:1998-03-13
标题:Methods for producing polypeptides through enhanced synthesis of encoding nucleic acid molecules
发明人：LI WU-BO; JESSEE JOEL A; SCHUSTER DAVID; XIA JIULIN; GEBEYEHU GULILAT
权利人:INVITROGEN CORP
摘要:The present invention is directed to compositions and methods for enhancing synthesis of nucleic acid molecules, particularly GC-rich nucleic acid molecules. Specifically, the invention provides compositions comprising one or more nitrogen-containing organic compounds having a formula selected from the group consisting of formula I and formula II (or salts or derivatives thereof), preferably 4-methylmorpholine N-oxide or betaine (carboxymethyltrimethylammonium), and further comprising one or more compounds selected from the group consisting of proline and an N-alkylimidazole compound, and more preferably proline, 1-methylimidazole or 4-methylimidazole. The invention further relates to methods for enhanced, high-fidelity synthesis of nucleic acid molecules, including via amplification (particularly PCR), reverse transcription, and sequencing methods. The invention also relates to nucleic acid molecules synthesized by these methods, to fragments or derivatives thereof, and to vectors and host cells comprising such nucleic acid molecules, fragments, or derivatives. The invention also relates to kits for synthesizing, amplifying, reverse transcribing or sequencing nucleic acid molecules comprising one or more of the compositions of the invention.

专利号:US-11603382-B2
优先权日:2015-12-11
标题 :Diastereoselective synthesis of phosphate derivatives
发明人：KOTALA MANI BUSHAN; DAMMALAPATI VENKATA LAKSHMI NARASIMHA RAO
权利人:NuCana plc
摘要:The present invention provides a method for the preparation of intermediates useful in the synthesis of gemcitabine-[phenyl-benzoxy-L-alaninyl)]-phosphate. It also provides a method of preparing gemcitabine-[phenyl-benzoxy-L-alaninyl)]-phosphate.

专利号:US-7037691-B2
优先权日:2001-07-02
标题:Kinase mimic catalysts for asymmetric synthesis of phosphorylated inositols and cycloalkanols
发明人：MILLER SCOTT J; SCULIMBRENE BIANCA; MORGAN ADAM J
权利人:TRUSTEES BOSTON COLLEGE
摘要:The present invention provides peptide-based phosphorylation catalysts (PBPC's) for the asymmetric monophosphorylation of cyclitols, particularly myo-inositols. The PBPC's of the invention effect a regio and enantioselective phosphorylation of a myo-inositol in a manner analogous to enzymatic kinases, thereby functioning as effective “kinase mimics.â€? Although orders of magnitude less complex in terms of structure than macromolecular proteins, the PBPC's of the invention control product formation with high enantioselectivity (>98% ee). The synthetic (+)-myo-inositol-1-phosphate is optically and spectroscopically equivalent to naturally occuring compound. The ability of the low molecular weight PBPC's of the present invention to mimic stereoselective enzymes represents a powerful approach toward catalytic asymmetric synthesis of biologically important molecules, and for mechanistic modeling of biochemical transformations to enable their use in drug applications.

专利号:US-6294664-B1
优先权日:1993-07-29
标 题:Synthesis of oligonucleotides
发明人：RAVIKUMAR VASULINGA; COLE DOUGLAS L
权利人:ISIS PHARMACEUTICALS INC
摘要:Synthetic processes are provided for the solution phase synthesis of oligonucleotides, especially phosphorothioate oligonucleotides, and intermediate compounds useful in the processes. Intermediates having structure (I) are prepared in accordance with preferred embodiments.

专利号:US-6870039-B2
优先权日:1993-07-29
标题 :Synthesis of oligonucleotides
发明人：RAVIKUMAR VASULINGA; COLE DOUGLAS L
权利人:ISIS PHARMACEUTICALS INC
摘要:Synthetic processes are provided for the solution phase synthesis of oligonucleotides, especially phosphorothioate oligonucleotides, and intermediate compounds useful in the processes. Intermediates having structure n n nare prepared in accord with preferred embodiments.

专利号:US-5571902-A
优先权日:1993-07-29
标题:Synthesis of oligonucleotides
发明人：RAVIKUMAR VASULINGA; COLE DOUGLAS L
权利人:ISIS PHARMACEUTICALS INC
摘要:Synthetic processes are provided for the solution phase synthesis of oligonucleotides, especially phosphorothioate oligonucleotides, and intermediate compounds useful in the processes. Intermediates having structure ##STR1## are prepared in accord with preferred embodiments.