CAS: 177582-21-7; Fmoc-Cys(Mmt)-Oh

相似化合物

269067-38-1 103213-32-7 167015-11-4

上下游产品

α-fluoren-9-ylmethoxycarbonyl-L-cysteineNα-fluoren-9-ylmethoxycarbonyl-L-cysteine mono-4-methoxytrityl chloride N,N'-bis[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cystine N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimidetrityl-Gly-Cys(palmitoyl)-Met-Gly-Leu-Pro-Cys(farnesyl) 47H68N16O13S2C47H68N16O13S2 cholest-5-en-3-yl (2R)-2-amino-3-{[(4-methoxyphenyl)(diphenyl)methyl]sulfanyl}propanoate 98H138N2O8SC98H138N2O8S

Fmoc-胱氨酸置于盐酸,锌体系中,用 水,乙酸乙酯,N,N-二甲基甲酰胺 用作溶剂,化学反应 3.0H,反应生成Fmoc-S-(4-甲氧基三苯甲基)-L-半胱氨酸
参考文献:Flemer,Stevenson,Protein And Peptide Letters,2014,Vol. 21,# 12,P. 1257-1264
标题:Flemer,Stevenson,Protein And Peptide Letters,2014,Vol. 21,# 12,P. 1257-1264

专利信息

专利号:US-12441760-B2
优先权日:2013-08-29
标 题 :Amino diacids containing peptide modifiers
发明人：BARLOS KLEOMENIS; GATOS DIMITRIOS; BARLOS KOSTAS K; VASILEIOU ZOI
权利人:CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S A
摘要:The present invention relates to peptide modifier compounds of Formula (1), or a salt thereof, wherein: a is an integer from 1 to 10, more preferably from 1 to 3; b is an integer from 0 to 7; Z is a terminal group and Y is a bivalent group. Further aspects of the invention relate to intermediates in the preparation of compounds of Formula (1), and the use of compounds of Formula (1) in the synthesis of peptide derivatives.

专利号:US-10442838-B2
优先权日:2015-12-18
标 题 :Linaclotide synthesis method
发明人：CHEN XUEMING; WU JINGKANG; MI PENGCHENG; TAO ANJIN; YUAN JIANCHENG
权利人:HYBIO PHARMACEUTICAL CO LTD
摘要:Disclosed is a method of synthesizing linaclotide through completely selective formation of three disulfide bonds, comprising the steps of: 1) synthesizing linaclotide precursor resin through solid-phase synthesis; 2) forming the first disulfide bond through solid phase oxidation; 3) forming the second disulfide bond through liquid phase oxidation; and 4) deprotecting methyl in the methyl-protected cysteine, and oxidatively coupling the third disulfide bond to obtain linaclotide. The method has mild reaction conditions with low cost, high yield and high purity product, is a simple and stable process and is suitable for large-scale production.

专利号:BR-112014026077-B1
优先权日:2012-04-20
标 题 :METHOD OF SOLID PHASE SYNTHESIS OF A PROTECTED, PARTIALLY PROTECTED OR UNPROTECTED INSULIN B CHAIN OR AN INSULIN B CHAIN DERIVATIVE, AND METHOD FOR PREPARING AN INSULIN B CHAIN PEPTIDE

专利号:WO-2013156977-A1
优先权日:2012-04-20
标 题 :Solid phase peptide synthesis of insulin using side chain anchored lysine

专利号:EP-3728304-B1
优先权日:2017-12-21
标题 :Solid phase synthesis of acylated peptides

专利号:US-2016031962-A1
优先权日:2012-04-20
标 题 :Solid phase peptide synthesis of insulin using side chain achored lysine