CAS: 3678-63-5; 4-Chloro-2-Picoline

相似化合物

3512-75-2 1010115-57-7 42779-56-6

上下游产品

CAS号26452-80-2 2,4-二氯吡啶 | CAS号75-16-1 甲基溴化镁 | CAS号931-19-1 2-甲基吡啶-N-氧化物 | CAS号5470-66-6 2-甲基-4-硝基氧化吡啶 | CAS号18437-58-6 4-氨基-2-甲基吡啶 | CAS号10025-87-3 三氯氧磷 | CAS号5470-22-4 4-氯-2-吡啶甲酸 | CAS号22468-26-4 4-羟基吡啶-2-羧酸 | CAS号660867-80-1 2-甲基吡啶-4-硼酸频哪酯 | CAS号63071-10-3 4-氯-2-吡啶甲醇 | CAS号63071-13-6 4-氯-2-吡啶甲醛 | CAS号139179-03-6 8-氯-1-乙基-4-氧代-4... | CAS号103971-16-0 2-甲基-4-(1-哌啶基)-吡啶 | CAS号104711-65-1 4-氯-6-甲基吡啶腈 | CAS号2214-53-1 2-甲基吡啶-4-甲腈 | CAS号18615-86-6 4-羟基-2-甲基吡啶

2-甲基吡啶氧化物置于硝酸体系中,用 乙醇,水,三氯氧磷 作为反应溶剂,化学反应生成 4-氯-2-甲基吡啶
参考文献:Quinolizinone Type Compounds
标题:Quinolizinone Type Compounds
摘要:具有以下结构式的抗菌化合物及其药学上可接受的盐,酯和酰胺,其中a为.Dbd.Cr.Sup.6-;r.Sup.1为含有三至八个碳原子的环烷基或取代苯基;r.Sup.2选自以下群体:##str2## R.Sup.3为卤素;r.Sup.4为氢,较低烷基,药学上可接受的阳离子或前药酯基团;r.Sup.5为氢,较低烷基,卤代(较低烷基)或--Nr.Sup.13 R.Sup.14 ;r.Sup.6为卤素,较低烷基,卤代(较低烷基),羟基取代的较低烷基,较低烷氧基(较低烷基),较低烷氧基或氨基(较低烷基),以及含有这类化合物的药物组合物以及将其用于治疗细菌感染.

专利信息

专利号:EP-0394263-B1
优先权日:1987-09-04
标 题 :Process for production of prostaglandin intermediates
发明人：SADDLER JOHN C; SYMONDS JOHN H
权利人:UPJOHN CO
摘要:The present invention is a process for the production of a ketolactone of formula (III) which comprises contacting and aldehyde lactone of formula (I) with a beta-ketophosphonate (X1-O-)2-PO-CH2-CO-X15 (II). The ketolactone (III) is a useful intermediate in the synthesis of prostaglandins.

专利号:US-5079371-A
优先权日:1987-09-04
标题:Process for production of prostaglandin intermediates
发明人：SADDLER JOHN C; SYMONDS JOHN H
权利人:UPJOHN CO
摘要:The present invention is a process for the production of a ketolactone of formula III ##STR1## which comprises contacting an aldehyde lactone of formula I ##STR2## with a β-ketophosphonate (X 1 --O--) 2 --PO--CH 2 --CO--X 15 (II). The ketolactone (III) is a useful intermediate in the synthesis of prostaglandins.

专利号:US-9676783-B2
优先权日:2008-10-22
标 题:Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds
发明人：HAAS JULIA; ANDREWS STEVEN W; JIANG YUTONG; ZHANG GAN
权利人:ARRAY BIOPHARMA INC
摘要:Compounds useful in the synthesis of compounds for treating pain, cancer, inflammation, neurodegenerative disease or Typanosoma cruzi infection in a mammal.

专利号:US-8853410-B2
优先权日:2009-04-30
标 题:Process for preparing substituted isoxazoline compounds and their precursors
发明人：RACK MICHAEL; KOERBER KARSTEN; KAISER FLORIAN
权利人:RACK MICHAEL; KOERBER KARSTEN; KAISER FLORIAN; BASF SE
摘要:The present invention relates to a new method of preparing halogenated styrene compounds of formula (VIII) n nwhich are precursors in the process of synthesis of substituted isoxazoline compounds of formula (I)n n nwherein R 1 to R 5 , R 8 and R 9 are described as in the description.n n The present invention relates further to the synthesis of compounds of formula (I) starting from acetophenones. The desired styrenes of formula are prepared from the appropriate substituted acetophenone. Asides bromo anilines react with formoxime. Obtained oximes undergo a cycloaddition with the styrenes and give isoxazolines. Compounds of formula (I) can then be prepared in a palladium catalyzed carbonylative amination reaction of the isoxazolines.

专利号:US-2009215080-A1
优先权日:2005-10-13
标题:Methods for identification of inhibitors of enzyme activity
发明人：SINHA SUKANTO; CHILCOTE TAMIE JO
权利人:ACTIVESITE PHARMACEUTICALS
摘要:The invention discloses compositions and methods of synthesis to create novel ligands and drugs and identifying such compounds as inhibitors of enzyme targets for use in the treatment of clinical disorders, including cancer, infectious diseases, parasitic infestations, neurological disorders, reproductive disorders, inflammatory disorders, circulatory disorders, and metabolic disorders.

专利号:RU-2070887-C1
优先权日:1989-06-02
标 题 :Method of synthesis of 17e- or 17z-isomers of silyl ester