CAS: 452-07-3; 1-(Chloromethyl)-2,4-Difluorobenzene

上下游产品

2,4-二氟甲苯 2,4-Difluorotoluene 452-76-6

5-氟-2-甲基苯胺置于氯体系中,化学反应生成 2,4-二氟氯苄
参考文献:Jerumanis,S.; Bruylants,A.,Bulletin Des Societes Chimiques Belges,1960,Vol. 69,P. 312-322
标题:Jerumanis,S.; Bruylants,A.,Bulletin Des Societes Chimiques Belges,1960,Vol. 69,P. 312-322

专利信息

专利号:US-4536599-A
优先权日:1978-08-22
标题:Synthesis of amine derivatives
发明人：MASUKO FUJIO; KATSURA TADASHI
权利人:SUMITOMO CHEMICAL CO
摘要:An amine of the formula, ##STR1## wherein R 1 , R 2 , R 3 , R 4 and R 5 are each hydrogen, alkyl or the like and n is 1, 2 or 3, including α-phenyl-β-(p-tolyl)-ethylamine, which is useful as an optically resolving agent, an intermediate of medicines and the like, is effectively produced by a novel process comprising hydrolysis of the corresponding nitrile of the formula, ##STR2## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above, followed by alkali-decomposition of the resulting amide of the formula, ##STR3## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above. An amide including the above one is effectively produced by hydrolysis of the corresponding nitrile in the presence of a base and hydrogen peroxide using an organic quaternary ammonium salt and/or a tertiary amine as a catalyst.

专利号:EP-0008532-A1
优先权日:1978-08-22
标 题 :Synthesis of amines

专利号:EP-0008532-B1
优先权日:1978-08-22
标 题 :Synthesis of amines

专利号:EP-0040896-A2
优先权日:1978-08-22
标 题 :Synthesis of amides

专利号:CN-115594689-B
优先权日:2022-07-14
标题:A kind of relugoli intermediate and a kind of synthesis method of relugoli