CAS: 5775-82-6; 4-Bromo-1,3-Dimethyl-1H-Pyrazole

相似化合物

1021919-24-3 5775-86-0 287922-71-8

上下游产品

CAS号25016-12-0 1,3-二甲基吡唑-4-甲醛 | CAS号694-48-4 1,3-二甲基吡唑 | CAS号78703-53-4 1,3-二甲基-1H-吡唑-4-羧酸 | CAS号13808-64-5 4-溴-3-甲基吡唑 | CAS号74-88-4 碘甲烷 | CAS号67-66-3 氯仿 | CAS号7726-95-6 溴素 | CAS号124-41-4 甲醇钠 | CAS号84547-86-4 4-溴-1-甲基-1H-吡唑-3-羧酸 | CAS号76689-64-0 5-氨基-1,3-二甲基-4-硝基吡唑 | CAS号1046832-21-6 1,3-二甲基-1H-吡唑-4... | CAS号76689-62-8 5-bromo-1,3-dim... | CAS号84547-91-1 4-BROMO-1-METHY... | CAS号5744-71-8 4,5-二溴-1,3-二甲基-1H-吡唑

1,3-二甲基-1H-吡唑-4-羧酸置于sodium Hydroxide,溴体系中,用 水 作为反应溶剂,化学反应 1.0H,以80%的收率获得产物4-溴-1,3-二甲基-1H-吡唑
参考文献:Bromination Of 1,3-Dimethyl-And 1,5-Dimethyl-1H-Pyrazole-4-Carboxylic Acids
标题:Bromination Of 1,3-Dimethyl-And 1,5-Dimethyl-1H-Pyrazole-4-Carboxylic Acids
摘要:
DOI:10.1134/s1070363207020193

专利信息

专利号:CN-113336703-B
优先权日:2021-05-17
标 题:Synthesis of 1,3,4,5-tetrasubstituted 1H-pyrazole derivatives

专利号:US-8633182-B2
优先权日:2012-05-30
标题:Indanyloxyphenylcyclopropanecarboxylic acids
发明人：HAMPRECHT DIETER; FRATTINI SARA; LINGARD IAIN; PETERS STEFAN
权利人:HAMPRECHT DIETER; FRATTINI SARA; LINGARD IAIN; PETERS STEFAN; BOEHRINGER INGELHEIM INT
摘要:The present invention relates to compounds of general formula I, n nwherein the groups R 1 , R 2 , R 3 , m and n are defined as in claim 1 , which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.

专利号:US-9925177-B2
优先权日:2015-01-22
标题:4-methylsulfonyl-substituted piperidine urea compounds
发明人：OSLOB JOHAN; AUBELE DANIELLE; KIM JAE; MCDOWELL ROBERT; SONG YONGHONG; SRAN ARVINDER; ZHONG MIN
权利人:MYOKARDIA INC
摘要:The present invention provides novel 4-methylsulphone-substituted piperidine urea compounds that are useful for the treatment of dilated cardiomyopathy (DCM) and conditions associated with left and/or right ventricular systolic dysfunction or systolic reserve. The synthesis and characterization of the compounds is described, as well as methods for treating DCM and other forms of heart disease.

专利号:CN-114716378-A
优先权日:2022-04-06
标题:Synthesis method of 1,3, 4-trisubstituted-5-cyanopyrazole derivative