专利号:US-5002641-A 优先权日:1990-06-28 标题:Electrochemical synthesis of niacin and other N-heterocyclic compounds 发明人:TOOMEY JR JOSEPH E 权利人:REILLY IND INC 摘要:An electrochemical oxidation of a pi-deficient N-heterocyclic precursor compound having an oxidizable organic group attached by a carbon-to-carbon linkage. This precursor compound is at least sparingly water soluble. The preferred electro-oxidation is conducted at an effective anode and in a medium which consists essentially of water, carboxylic acid, and the precursor compound. Preferred are electro-oxidations of substituted pyridine and quinoline bases and a particularly preferred aspect provides a convenient electrochemical synthesis of niacin from 3-methylpyridine.
专利号:US-6174956-B1 优先权日:1995-06-02 标题 :Synthesis of condensation polymers in densified fluids 发明人:KERSCHNER JUDITH LYNNE; JURELLER SHARON HARRIOTT; THOMAIDES JOHN SOCRATES; HUMPHREYS ROBERT WILLIAM; IOVINE CARMINE PHILLIP 权利人:NAT STARCH CHEM INVEST 摘要:A polyurethane polymer and method of preparing it is described. The process requires the combination of a soluble polyol with a di- or polyisocyanate under densified fluid conditions. The process to prepare a waterborne polyurethane involves the utilization of a polyol containing ionic or latent ionic groups which must undergo preneutralization before combining with the di- or polyisocyanate under densified fluid conditions. The resulting polyurethane is substantially free of an organic solvent.
专利号:US-12071507-B2 优先权日:2014-01-10 标 题:Method and composition for improving adhesion of metathesis compositions to substrates 发明人:STEPHEN ANTHONY R; CRUCE CHRISTOPHER J; TRIMMER MARK S; GIARDELLO MICHAEL A 权利人:MATERIA INC 摘要:A method of improving the adhesion of metathesis compositions, such as ring-opening metathesis polymerization (ROMP) compositions, to a substrate is disclosed, in which an adhesion promoter is added to a polymerizable resin composition in order to improve the adhesion of the polymerizing resin to a substrate material. The addition of the adhesion promoter has been found to provide beneficial improvements in the adhesion of metathesis, especially ROMP, compositions to substrates, particularly glass surfaces, leading to improved characteristics in ROMP materials formed therefrom. The adhesion promoter generally comprises a functionalized silane compound and a peroxide compound. A ROMP composition is further disclosed comprising a cyclic olefin, a ROMP metathesis catalyst, and the adhesion promoter. Polymer products produced via metathesis (ROMP) reactions of the invention may be utilized to provide a wide range of materials and in a variety of composite applications. The invention has utility in the fields of catalysis, organic synthesis, and polymer and materials chemistry and manufacture.
专利号:US-8841457-B2 优先权日:2010-11-15 标题:Process for cyclooxygenase-2 selective inhibitor 发明人:SHAH DHARMESH MAHENDRA; SOLANKI SANJAY AMRATLAL; JARIWALA VIRAL NARENDRA; VYAS ASHOK VASANTRAY; MISTRY ASHOKKUMAR BHIKHUBHAI 权利人:SHAH DHARMESH MAHENDRA; SOLANKI SANJAY AMRATLAL; JARIWALA VIRAL NARENDRA; VYAS ASHOK VASANTRAY; MISTRY ASHOKKUMAR BHIKHUBHAI; VIRDEV INTERMEDIATES PVT LTD 摘要:The present invention describes a process for preparing a cyclooxygenase-2 selective inhibitor. It provides a synthetic procedure for the said substance namely 5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine of formula (I). The invention also relates to preparation of a new intermediate of formula (IV) and a process to prepare it. Furthermore, the invention describes a process for preparing another key intermediate of formula (II). Compounds of formula (IV) and formula (II) are useful intermediates in synthesis of the said cyclooxygenase-2 inhibitor.
专利号:WO-9200403-A1 优先权日:1990-06-28 标题 :Electrochemical synthesis of niacin and other n-heterocyclic compounds
专利号:EP-0536309-A1 优先权日:1990-06-28 标 题 :Electrochemical synthesis of niacin and other n-heterocyclic compounds
参考文献:10.1007/s00706-024-03252-x 摘要:Samanta SK, Patra S, Biswas B, Patra AH, Ghosh P, Mistri T, Rout D, Patra P. Recent advances on the synthesis of pyrido[3,4-c]coumarin derivatives as the backbone of natural product schumanniophytin scaffolds. Monatsh Chem. 2024 Oct 06;155(11):997–1026. doi: 10.1007/s00706-024-03252-x.