CAS: 5860-71-9; 2,6-Dimethylnicotinic Acid

该化合物是硝酸的一种衍生物,其特点是在环的2和6个位置上存在两个甲基组,该化合物是一种在水和有机溶剂中溶解的白到白的晶状固体,反映其极性,由于碳oxylic酸功能组,反映了其极性.它有一个CHNO分子配方,表明碳,氢,氮和氧原子的存在.复合物的酸性,典型的碳酸,可以参与各种化学反应,包括酯化和恐吓.它与硝基酸相比的结构改变可能会影响其生物活动,使其对药物研究感兴趣.此外,2,6-二甲基硝基酸可以作为有机合成的建筑块,并可用于发展农业化学品或其他特殊化学品.应该参考安全数据,以便处理和使用,正如所有化学物质一样.

结构式图片

相似化合物

582303-10-4 3222-56-8 757903-81-4

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上下游产品

ethyl 2,6-dimethylnicotinate 2,6-dimethyl-3-hydroxypyridine carbon dioxide trans-styryl)-nicotinic acid2-methyl-6-(3-nitro-trans-styryl)-nicotinic acid trans-styryl)-nicotinic acid2,6-bis-(3-nitro-trans-styryl)-nicotinic acid 2-Methyl-6-styryl-3-nicotinic acid 2,6-dimethylpyridine

合成工艺路线路线简述

    2,6-二甲基烟酸乙酯/2,6-二甲基-3-羧酸甲酯置于sodium Hydroxide体系中,化学反应生成 2,6-二甲基烟酸
    参考文献:De936448
    标题:De936448

    海关参考信息

    专利信息


    专利号:US-5002641-A
    优先权日:1990-06-28
    标题:Electrochemical synthesis of niacin and other N-heterocyclic compounds
    发明人:TOOMEY JR JOSEPH E
    权利人:REILLY IND INC
    摘要:An electrochemical oxidation of a pi-deficient N-heterocyclic precursor compound having an oxidizable organic group attached by a carbon-to-carbon linkage. This precursor compound is at least sparingly water soluble. The preferred electro-oxidation is conducted at an effective anode and in a medium which consists essentially of water, carboxylic acid, and the precursor compound. Preferred are electro-oxidations of substituted pyridine and quinoline bases and a particularly preferred aspect provides a convenient electrochemical synthesis of niacin from 3-methylpyridine.

    专利号:US-6174956-B1
    优先权日:1995-06-02
    标题 :Synthesis of condensation polymers in densified fluids
    发明人:KERSCHNER JUDITH LYNNE; JURELLER SHARON HARRIOTT; THOMAIDES JOHN SOCRATES; HUMPHREYS ROBERT WILLIAM; IOVINE CARMINE PHILLIP
    权利人:NAT STARCH CHEM INVEST
    摘要:A polyurethane polymer and method of preparing it is described. The process requires the combination of a soluble polyol with a di- or polyisocyanate under densified fluid conditions. The process to prepare a waterborne polyurethane involves the utilization of a polyol containing ionic or latent ionic groups which must undergo preneutralization before combining with the di- or polyisocyanate under densified fluid conditions. The resulting polyurethane is substantially free of an organic solvent.

    专利号:US-12071507-B2
    优先权日:2014-01-10
    标 题:Method and composition for improving adhesion of metathesis compositions to substrates
    发明人:STEPHEN ANTHONY R; CRUCE CHRISTOPHER J; TRIMMER MARK S; GIARDELLO MICHAEL A
    权利人:MATERIA INC
    摘要:A method of improving the adhesion of metathesis compositions, such as ring-opening metathesis polymerization (ROMP) compositions, to a substrate is disclosed, in which an adhesion promoter is added to a polymerizable resin composition in order to improve the adhesion of the polymerizing resin to a substrate material. The addition of the adhesion promoter has been found to provide beneficial improvements in the adhesion of metathesis, especially ROMP, compositions to substrates, particularly glass surfaces, leading to improved characteristics in ROMP materials formed therefrom. The adhesion promoter generally comprises a functionalized silane compound and a peroxide compound. A ROMP composition is further disclosed comprising a cyclic olefin, a ROMP metathesis catalyst, and the adhesion promoter. Polymer products produced via metathesis (ROMP) reactions of the invention may be utilized to provide a wide range of materials and in a variety of composite applications. The invention has utility in the fields of catalysis, organic synthesis, and polymer and materials chemistry and manufacture.

    专利号:US-8841457-B2
    优先权日:2010-11-15
    标题:Process for cyclooxygenase-2 selective inhibitor
    发明人:SHAH DHARMESH MAHENDRA; SOLANKI SANJAY AMRATLAL; JARIWALA VIRAL NARENDRA; VYAS ASHOK VASANTRAY; MISTRY ASHOKKUMAR BHIKHUBHAI
    权利人:SHAH DHARMESH MAHENDRA; SOLANKI SANJAY AMRATLAL; JARIWALA VIRAL NARENDRA; VYAS ASHOK VASANTRAY; MISTRY ASHOKKUMAR BHIKHUBHAI; VIRDEV INTERMEDIATES PVT LTD
    摘要:The present invention describes a process for preparing a cyclooxygenase-2 selective inhibitor. It provides a synthetic procedure for the said substance namely 5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine of formula (I). The invention also relates to preparation of a new intermediate of formula (IV) and a process to prepare it. Furthermore, the invention describes a process for preparing another key intermediate of formula (II). Compounds of formula (IV) and formula (II) are useful intermediates in synthesis of the said cyclooxygenase-2 inhibitor.

    专利号:WO-9200403-A1
    优先权日:1990-06-28
    标题 :Electrochemical synthesis of niacin and other n-heterocyclic compounds

    专利号:EP-0536309-A1
    优先权日:1990-06-28
    标 题 :Electrochemical synthesis of niacin and other n-heterocyclic compounds
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    合成参考文献


    参考文献:10.1007/s00706-024-03252-x
    摘要:Samanta SK, Patra S, Biswas B, Patra AH, Ghosh P, Mistri T, Rout D, Patra P. Recent advances on the synthesis of pyrido[3,4-c]coumarin derivatives as the backbone of natural product schumanniophytin scaffolds. Monatsh Chem. 2024 Oct 06;155(11):997–1026. doi: 10.1007/s00706-024-03252-x.
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