CAS: 10557-85-4; 3,5-Dimethyl-4-Iodoisoxazole

相似化合物

7064-38-2 300-87-8 1936273-38-9

上下游产品

CAS号300-87-8 3,5-二甲基异唑 | CAS号16114-47-9 3,5-二甲基异唑-4-硼酸 | CAS号300-87-8 3,5-二甲基异唑 | CAS号38604-92-1 4-(3,5-dimethyl... | CAS号75632-81-4 3,5-dimethyl-4-... | CAS号832114-00-8 3,5-二甲基异恶唑-4-硼酸频哪醇酯 | CAS号154822-66-9 4-(4-Methoxyphe... | CAS号136295-80-2 4-三丁基锡烷基-3,5-二甲基异恶唑 | CAS号16114-47-9 3,5-二甲基异唑-4-硼酸 | CAS号75632-83-6 trimethyl-[(3-m... | CAS号668970-91-0 4-乙炔基-3,5-二甲基异恶唑

3,5-二甲基异唑置于碘,Silver(I) Acetate体系中,用 二氯甲烷 用作溶剂,以98%的收率获得3,5-二甲基-4-碘基异恶唑
参考文献:一种新的,温和的一锅法合成碘代杂环化合物,作为适合于n-杂环卡宾配合物的前体
标题:一种新的,温和的一锅法合成碘代杂环化合物,作为适合于n-杂环卡宾配合物的前体
摘要:在二氯甲烷中使用i 2 / Agoac构成了一种廉价,温和且有效的方法,可用于多种杂环的选择性碘化.在许多情况下,该方法比其他文献方法提供更高的收率,并提供了碘官能化的杂环,这些杂环是卡宾络合物的合适前体.
Doi:10.1016/j.Tetlet.2010.07.178

专利信息

专利号:US-4348525-A
优先权日:1981-04-09
标题 :Composition and a process for the preparation of [hydroxy(organosulfonyloxy)iodo]arenes and their use in a regiospecific synthesis of diaryliodonium salts
发明人：KOSER GERALD F; WETTACH RICHARD H
权利人:UNIV AKRON
摘要:[Hydroxy(organosulfonyloxy)iodo]arenes are synthesized in neutral organic solvents by the reaction of ring-substituted [hydroxy(organosulfonyloxy)iodo]benzenes with iodoarenes via ligand transfer. The produced compounds are reacted with (triorganosilyl) arenes or (trihalosilyl)arenes in neutral organic solvents to produce diaryliodonium salts. The diaryliodonium salt synthesis proceeds in regiospecific fashion, aryliodination occurring at the point of attachment of the silicon atom in the silylarenes.

专利号:US-4826635-A
优先权日:1981-04-09
标题:Composition and a process for the preparation of (hydroxy (organosulfonyloxy)iodo)arenes and their use in a regiospecific synthesis of diaryliodonium salts
发明人：KOSER GERALD F; WETTACH RICHARD H
权利人:UNIV AKRON
摘要:[Hydroxy(organosulfonyloxy)iodo]arenes are synthesized in neutral organic solvents by the reaction of ring-subsituted [hydroxy(organosulfonyloxy)iodo]benzenes with iodoarenes via ligand transfer. The produced compounds are reacted with (triorganosilyl) arenes or (trihalosilyl)arenes in neutral organic solvents to produce diaryliodonium salts. The diaryliodonium salt synthesis proceeds in regiospecific fashion, aryliodination occurring at the point of attachment of the silicon atom in the silylarenes.

专利号:US-2021284668-A1
优先权日:2018-06-19
标题:Gold (i)-phosphine 1,2,3-triazole derivatives with antibiotic properties
发明人：MISLIN GAËTAN; SCHALK ISABELLE; PLÉSIAT PATRICK; PAULEN AURÉLIE
权利人:CENTRE NAT RECH SCIENT; UNIV FRANCHE COMTE; CENTRE HOSPITALIER REGIONAL UNIV DE BESANCON; UNIV STRASBOURG
摘要:The present invention relates to gold (I)-phosphine 1,2,3-triazole compounds, and their use in a human or animal medicine. The present invention also relates to using such compounds for the prevention and/or treatment of an infection, i.e. inhibitors of growth of Gram-positive and/or Gram-negative bacteria. On another aspect the invention relates to the synthesis of the gold (I)-phosphine compounds of the invention and to their synthesis intermediates. The present invention finds applications in the medical, veterinary and/or chemical fields.

专利号:CN-104892547-A
优先权日:2015-05-14
标题 :Catalytic carbonylation method for synthesis of alpha-keto amide

专利号:US-9856241-B2
优先权日:2013-07-03
标 题:Substituted benzofuranyl and benzoxazolyl compounds and uses thereof
发明人：BALOGLU ERKAN; SHACHAM SHARON; SENAPEDIS WILLIAM; MCCAULEY DILARA; LANDESMAN YOSEF; GOLAN GALI; KALID ORI; SHECHTER SHARON
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to substituted benzofuranyl and substituted benzoxazolyl compounds, and more particularly to a compound represented by Structural Formula (A): or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of Structural Formula (A), or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders.