专利号:US-2023313255-A1 优先权日:2020-07-15 标题:Massively Parallel Enzymatic Synthesis of Polynucleotides 发明人:HORGAN ADRIAN; LACHAIZE HENRI; VERARDO DOMIANO; GODRON XAVIER 权利人:DNA SCRIPT 摘要:The invention is directed to methods and compositions for inkjet assisted synthesis of a plurality of polynucleotides at reaction sites on a substrate using template-free polymerases, such as, terminal deoxynucleotidyl transferases (TdTs). Compositions of the invention include formulations of synthesis reagents for inkjet delivery including, but not limited to, TdT coupling reaction buffers and 3′-O-protected dNTP monomers.
专利号:US-6534637-B2 优先权日:2001-02-12 标 题 :Synthesis of chlorophenol red glucuronic acid 发明人:SHEN GENE G Y; OH CHAN S; YANCEY STEPHANIE D; ADAMS CRAIG W 权利人:BECKMAN COULTER INC 摘要:This invention provides beta-D-Glucuronidase substrates of the formula:whereinR1, R2, and R7-R12 are independently selected from the group consisting of:hydrogen, fluorine, chlorine, bromine, iodine, alkyl, hydroxyl, alkoxy, carboxyl and nitro groups;R3-R6 are independently selected from the group consisting of hydrogen, fluorine, chlorine, bromine, iodine, nitro and amino; andM+ is selected from the group consisting of: proton, lithium, sodium, potassium, magnesium, calcium, barium, and ammonium ion.
专利号:US-9976179-B2 优先权日:2011-03-30 标 题 :Nucleic acid sequencing technique using a pH-sensing agent 发明人:HAUSHALTER ROBERT C 权利人:PARALLEL SYNTHESIS TECH; PARALLEL SYNTHESIS TECH INC 摘要:The invention relates to a composition, method and apparatus for determining the sequence of a nucleic acid strand utilizing a pH-sensing agent.
专利号:US-9868767-B2 优先权日:2013-05-23 标 题:Chemical synthesis and screening of bicyclic peptide libraries 发明人:PEI DEHUA; UPADHYAYA PUNIT; LIAN WENLONG; TRINH THI 权利人:OHIO STATE INNOVATION FOUNDATION 摘要:Disclosed herein are bicyclic peptide compounds, compositions comprising same, methods for making same, and libraries comprising same. The disclosed compounds, in various aspects, are useful for treating a variety of disorders, including inflammatory disorders, autoimmune disorders, and disorders of uncontrolled cellular proliferation. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
专利号:EP-1368363-A2 优先权日:2001-02-12 标 题 :Synthesis of chlorophenol red glucoronic acid
专利号:WO-2022013094-A1 优先权日:2020-07-15 标 题 :Massively parallel enzymatic synthesis of polynucleotides
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