3-氟邻二甲苯置于硝酸体系中,化学反应生成 3-氟-2-甲基苯甲酸 参考文献:Synthesis Of 8-Fluoro-10-Methyl-1,2-Benzanthracene1 标题:Synthesis Of 8-Fluoro-10-Methyl-1,2-Benzanthracene1 摘要: DOI:10.1021/jo01067A042
专利号:US-9217012-B2 优先权日:2009-04-08 标题 :Inhibitors of protein tyrosine phosphatases 发明人:ZHANG ZHONG-YIN; ZHANG SHENG 权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP 摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.
专利号:US-5846993-A 优先权日:1992-12-22 标题:HIV protease inhibitors 发明人:DRESSMAN BRUCE A; FRITZ JAMES E; KALDOR STEPHEN W; KALISH VINCENT J; REICH SIEGFRIED HEINZ; TATLOCK JOHN H; RODRIGUEZ MICHAEL J 权利人:AGOURON PHARMA 摘要:HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.
专利号:RU-2126006-C1 优先权日:1993-07-29 标 题:Tricyclic diazepine vasopressin and oxytocin antagonists, method of their synthesis, pharmaceutical composition, method of treatment
专利号:US-6271235-B1 优先权日:1992-12-22 标题:HIV protease inhibitors 发明人:DRESSMAN BRUCE A; FRITZ JAMES E; KALDOR STEPHEN W; KALISH VINCENT J; REICH SIEGFRIED HEINZ; RODRIGUEZ MICHAEL J; SHEPHERD TIMOTHY A; TATLOCK JOHN H; JUNGHEIM LOUIS NICKOLAUS 权利人:AGOURON PHARMA 摘要:HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.
专利号:CN-117024342-A 优先权日:2023-08-16 标题:A kind of synthesis method of phenanthridine OLED material
专利号:CN-117024342-B 优先权日:2023-08-16 标题:Synthesis method of phenanthridine OLED material
[参考文献]: K L Londry, Et Al. Use Of Fluorinated Compounds To Detect Aromatic Metabolites From M-Cresol In A Methanogenic Consortium: Evidence For A Demethylation Reaction. Appl Environ Microbiol. 1993 Jul;59(7):2229-38.
合成参考文献
参考文献:10.1007/978-3-662-10302-9_46 摘要:de Groot AC, Frosch PJ. Patch Test Concentrations and Vehicles for Testing Contact Allergens. 2001. In: Textbook of Contact Dermatitis. : Springer Berlin Heidelberg; 2001.