CAS: 3425-46-5; Potassium Selenocyanate

该化合物是一种无机化合物,配有化学配方KSeCN;一种白色的黄色晶状固体,在水和极有机溶剂中可溶解;该化合物主要用于合成化学,作为静电离子(SeCN)的一种来源,作为多用途悬离和配合化学和催化的凝聚剂;还用于制备含有的有机化合物,如Selinouryas和Selenoethers,因为它与烷卤化物和其他电解物发生反应;其稳定性和处理的方便性使其成为实验室规模应用的实用再生剂;由于化合物的毒性,有必要采取适当的安全防范措施.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号151-50-8 氰化钾 | CAS号70983-16-3 triphosphorus(I... | CAS号1116-01-4 tricyanophosphine | CAS号51694-22-5 2-硝基苯基丝氰酸酯 | CAS号21856-93-9 p-Tolyl selen°C... | CAS号2179-80-8 METHYLSELEN°CYANATE | CAS号19188-18-2 Selen°Cyanic ac... | CAS号2180-01-0 cyano selen°Cyanate | CAS号675-63-8 bis(dichloroflu... | CAS号692-58-0 chloro-[[chloro...

合成工艺路线路线简述

  • 合成目标产物 Potassium Selenocyanate 主要起始原料 Potassium Cyanate And Selenium
  • (文献来源)合成步骤主要原料 Potassium Cyanate 和 Selenium

专利信息


专利号:US-5512668-A
优先权日:1991-03-06
标 题 :Solid phase oligonucleotide synthesis using phospholane intermediates
发明人:STEC WOJCIECH J; GRAJKOWSKI ANDRZEJ; UZNANSKI BOGDAN
权利人:POLISH ACADEMY OF SCIENCES
摘要:Methods and compounds are provided for solid phase synthesis of oligonucleotides and related polymers by condensing protected monomer-O- 1,3,2-dichalcogen-substituted-phospholane! synthons in the presence of a catalytic base. Compounds of the invention include 2-N-substituted-1,3,2-dichalcogen-substituted-phospholane precursors of the above synthons, the protected monomer-O- 1,3,2-dichalcogen-substituted-phospholane! synthons, and P-chiral oligonucleotides and related P-chiral polymers.

专利号:US-2025171493-A1
优先权日:2022-03-05
标题 :Processes for synthesis of withanolides and withaferins and analogs thereof
发明人:LOPCHUK JUSTIN MATTHEW
权利人:H LEE MOFFITT CANCER CT & RES
摘要:The present disclosure provides processes for the synthesis of withanolides such as Withanolide A and Withanolide D.

专利号:US-5646267-A
优先权日:1991-08-05
标 题:Method of making oligonucleotides and oligonucleotide analogs using phospholanes and enantiomerically resolved phospholane analogues
发明人:STEC WOJCIECH J; GRAJKOWSKI ANDRZEJ; UZNANSKI BOGDAN
权利人:POLISH ACADEMY OF SCIENCES
摘要:Methods and compounds are provided for solid phase synthesis of oligonucleotides and related polymers by condensing protected monomer-O-[1,3,2-dichalcogen-substituted-phospholane] synthons in the presence of a catalytic base. Compounds of the invention include 2-N-substituted-1,3,2-dichalcogen-substituted-phospholane precursors of the above synthons, the protected monomer-O-[1,3,2-dichalcogen-substituted-phospholane] synthons, and P-chiral oligonucleotides and related P-chiral polymers.

专利号:US-2025115557-A1
优先权日:2022-02-16
标题:Total syntheses of selenoneine, iso-selenoneine, and isomers
发明人:ACHOUBA ADEL; AYOTTE PIERRE
权利人:UNIV LAVAL
摘要:A process for the total synthesis of selenoneine, iso-selenoneine, and isomers thereof is disclosed herein. Regarding the synthesis of selenoneine, the process comprises reacting an alkylated L-histidine methyl ester with a stable, acid-labile alkylating agent followed by reaction with elemental selenium under mildly basic conditions; and an acidic hydrolysis step. Regarding the synthesis of iso-selenoneine, the process comprises reacting hercynine with an electrophilic R—Se—X species, wherein the R—Se—X species is obtained by reaction of an alkyl diselenide with X 2 , and wherein X is F, Cl, Br or I; and a deprotection reaction.

专利号:US-2023295162-A1
优先权日:2020-08-06
标 题 :Synthesis of novel imipridone derivatives and their evaluation for their anticancer activity
发明人:CSÃ?MPAI ANTAL; BÃ?RÃ?NY PÉTER; CZUCZI TAMÃ?S; Kovács Imre; ADAMIS BÃ?LINT; NÉMETH ZSÓFIA; MURÃ?NYI JÓZSEF; OLÃ?HNÉ SZABÓ RITA; BOSZE SZILVIA; MEZO GÃ?BOR; KOHIDAI LÃ?SZLÓ; LAJKÓ ESZTER; TAKÃ?CS ANGÉLA; Láng Orsolya; MEZO DIÃ?NA
权利人:EOETVOES LORAND TUDOMANYEGYETEM; SEMMELWEIS EGYETEM
摘要:The present invention relates to compounds of formula (I) (I) or pharmaceutically acceptable salts, and stereoisomers thereof, including enantiomers, racemic mixtures, mixtures of enantiomers, or combinations thereof, which are applicable for use in treating cancer diseases. The present invention further relates to a pharmaceutical composition comprising the above compounds.

专利号:US-5883237-A
优先权日:1991-08-05
标 题:Oligonucleotides having Rp and Sp linkages at predetermined locations
发明人:STEC WOJCIECH J; GRAJKOWSKI ANDRZEJ; UZNANSKI BOGDAN
权利人:POLISH ACADEMY OF SCIENCE
摘要:Methods and compounds are provided for solid phase synthesis of oligonucleotides and related polymers by condensing protected monomer-O- 1,3,2-dichalcogen-substituted-phospholane! synthons in the presence of a catalytic base. Compounds of the invention include 2-N-substituted-1,3,2-dichalcogen-substituted-phospholane precursors of the above synthons, the protected monomer-O- 1,3,2-dichalcogen-substituted-phospholane! synthons, and P-chiral oligonucleotides and related P-chiral polymers.
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主要参考文献

[参考文献]: Bala Krishna Pathem, Et Al. Capillary Electrophoretic Determination Of Selenocyanate And Selenium And Tellurium Oxyanions In Bacterial Cultures. Anal Biochem. 2007 May 15;364(2):138-44.
[参考文献]: Kelly L Leblanc, Et Al. Production And Release Of Selenocyanate By Different Green Freshwater Algae In Environmental And Laboratory Samples. Environ Sci Technol. 2012 Jun 5;46(11):5867-75.
[参考文献]: Mark P De Souza, Et Al. Selenium Assimilation And Volatilization From Selenocyanate-Treated Indian Mustard And Muskgrass. Plant Physiol. 2002 Feb;128(2):625-33.
[参考文献]: Melissa A Crampsie, Et Al. Phenylalkyl Isoselenocyanates Vs Phenylalkyl Isothiocyanates: Thiol Reactivity And Its Implications. Chem Biol Interact. 2012 Oct 25;200(1):28-37.
[参考文献]: Nasir Baig Rashid Baig, Et Al. Synthesis Of Unnatural Selenocystines And Beta-Aminodiselenides Via Regioselective Ring-Opening Of Sulfamidates Using A Sequential, One-Pot, Multistep Strategy. J Org Chem. 2010 May 7;75(9):2910-21.

合成参考文献


摘要:National Technical Information Service., OTS0536978
摘要:National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review., 5(28), 1953
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