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CAS号78-38-6 乙基膦酸二乙酯 | CAS号541-41-3 氯甲酸乙酯 | CAS号74-96-4 溴乙烷 | CAS号535-11-5 2-溴丙酸乙酯 | CAS号122-52-1 亚磷酸三乙酯 | CAS号867-13-0 磷酰基乙酸三乙酯 | CAS号74-88-4 碘甲烷 | CAS号74-83-9 溴甲烷 | CAS号101834-92-8 bromo-2 phospho... | CAS号109307-90-6 ethyl 2-methyl-... | CAS号5962-41-4 2-膦酰基丙酸 | CAS号20345-61-3 Ethyl 2-(dietho... | CAS号24642-00-0 ethyl 2-methylp... | CAS号30094-28-1 2-(DIETHYLPHOSP... | CAS号6323-97-3 DL-1-氨基乙基膦酸 | CAS号107905-52-2 2-[双(2,2,2-三氟乙基... | CAS号52750-05-7 ethyl 3-(4-meth... | CAS号122-66-7 1,2-二苯肼 | CAS号163119-24-2 ethyl 2-(bis(o-...合成工艺路线路线简述
- 合成目标产物 Triethyl 2-Phosphonopropionate 主要起始原料 Ethyl Propionate
- (文献来源)合成步骤主要原料 Ethyl Propionate
丙酸乙酯置于六甲基磷酰三胺,Lithium Diisopropyl Amide体系中,用 四氢呋喃 作为反应溶剂,化学反应 3.0H,反应生成 三乙基2-膦酰基丙酯
参考文献:Synthesis Of .Alpha.-Phosphono Lactones And Esters Through A Vinyl Phosphate-Phosphonate Rearrangement
标题:Synthesis Of .Alpha.-Phosphono Lactones And Esters Through A Vinyl Phosphate-Phosphonate Rearrangement
摘要:
DOI:10.1021/jo00281A012
海关参考信息
- 2905121000-正丙醇
2909110000-乙醚
2912110000-甲醛
2912120000-乙醛 - 💡 提示:海关信息按照顺序优先匹配,如需确认的海关信息,请参考相关资料。
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专利信息
专利号:US-2025171493-A1
优先权日:2022-03-05
标题 :Processes for synthesis of withanolides and withaferins and analogs thereof
发明人:LOPCHUK JUSTIN MATTHEW
权利人:H LEE MOFFITT CANCER CT & RES
摘要:The present disclosure provides processes for the synthesis of withanolides such as Withanolide A and Withanolide D.
专利号:US-6710208-B2
优先权日:1996-12-19
标题 :Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds
发明人:SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARMA INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.
专利号:US-9464021-B2
优先权日:2013-11-01
标题 :Method of preparation of stereospecific quinone derivatives
发明人:MEHTA DILIP S; MOHAN PRIYA; SHASTRI MAYANK; REID TED
权利人:MEHTA DILIP S; MOHAN PRIYA; SHASTRI MAYANK; REID TED
摘要:The description provides processes for the regio and stereospecific synthesis of polyprenylatedquinone derivatives, such as Vitamin K1, K2 and Ubiquinone, exploiting dithioacetals, especially 1,3-dithiane, mediated Umpolung chemistry which works along a new concept “Inhibiting resonance delocalization (IRD)â€? to overcome isomerization generated due to delocalization of allyliccarbanion on the Ï€-electron cloud of an allylic systems by the conventional synthesis.
专利号:EP-0468457-B1
优先权日:1990-07-24
标题 :Novel substituted piperidines and their use as inhibitors of cholesterol synthesis
发明人:MCCARTHY JAMES R; BARNEY CHARLOTTE L; WANNAMAKER MARION W
权利人:MERRELL DOW PHARMA
摘要:The present invention relates to a group of compounds which are novel substituted piperidines and which act to inhibit the synthesis of cholesterol in mammals and in fungi.
专利号:US-7968736-B2
优先权日:2002-09-06
标 题:Analogs of discodermolide and dictyostatin-1, intermediates therefor and methods of synthesis thereof
发明人:CURRAN DENNIS P; SHIN YOUSEUNG; CHOY NAKYEN; DAY BILLY W; BALACHANDRAN RAGHAVAN; MADIRAJU CHARITHA; TURNER TIFFANY
权利人:UNIV PITTSBURGH & MDASH OF THE COMMONWELTH SYSTEMS OF HIGHER EDUCATION
摘要:A compound of the following structure: n n n n n n n n n n wherein R 1 is H, an alkyl group, an aryl group, an alkenyl group, an alkynyl group, or a halogen atom; n R 2 is H, an alkyl group, an aryl group, a benzyl group, a trityl group, —SiR a R b R c , CH 2 OR d , or COR e ; n R a , R b and R c are independently an alkyl group or an aryl group; n R d is an alkyl group, an aryl group, an alkoxylalkyl group, —R i SiR a R b R c or a benzyl group, wherein R i is an alkylene group; n R e is an alkyl group, an allyl group, a benzyl group, an aryl group, an alkoxy group, or —NR g R h , wherein R g and R h are independently H, an alkyl group or an aryl group; n R 3 is (CH 2 ) n where n is and integer in the range of 0 to 5, —CH 2 CH(CH 3 )—, —CHâ•?CH—, —CHâ•?C(CH 3 )—, or —C≡C—; n R 4 n n n n n n n n n n n n  wherein y1 and y2 are 1 and y3, y4 and y5 are independently 0 or 1, R k1 , R k2 , R k3 , R k4 and R k5 are independently H, CH 3 , or OR 2a , and R s1 , R s2 , R s3 , and R s4 are independently H or CH 3 , wherein R 2a is H, an alkyl group, an aryl group, a benzyl group, a trityl group, —SiR a R b R c , CH 2 OR d , or COR e ; and n R 5 is H or OR 2b , wherein R 2b is H, an alkyl group, an aryl group, an aryl group,a benzyl group, a trityl group, —SiR a R b R c , CH 2 OR d , or COR e .
专利号:US-12378246-B2
优先权日:2019-04-11
标 题:Synthetic options towards the manufacture of (6R,10S)-10-{4-[5-chloro-2-(4-chloro-1H-1,2,3-triazol-1-yl)phenyl]-6-oxo-1(6H)-pyrimidinyl} - 1-(difluoromethyl)-6-methyl-1,4,7,8,9,10-hexahydro-11,15-(metheno)pyrazolo[4,3-b][1,7]diazacyclotetradecin-5(6H)-one
发明人:CUNIERE NICOLAS; FAN YU; KOLOTUCHIN SERGEI; MUKHERJEE SUBHA; SIMMONS ERIC M; SINGH AMARJIT; WEI CAROLYN S; XIAO YI; YUAN CHANGXIA; ZHENG BIN; WAGSCHAL SIMON ALBERT; BROGGINI DIEGO FERNANDO DOMENICO; CAO DUY CHI TRUNG; CHERNICHENKO KOSTIANTYN; LEMAIRE SEBASTIEN FRANCOIS EMMANUEL; BEN HAÃ?M CYRIL
权利人:BRISTOL MYERS SQUIBB CO; JANSSEN PHARMACEUTICA NV
摘要:Highly efficient methods are provided for preparing key intermediates in the synthesis of Compound (I), which are broadly applicable and can provide selected components having a variety of substituents groups.