CAS: 977-79-7; Medrogestone

上下游产品

CAS号20867-46-3 3beta-hydroxy-6... | CAS号106598-97-4 3β-Hydroxy-17α-... | CAS号25352-87-8 (17S)-3β-hydrox... | CAS号5087-55-8 6α,17-Dimethylp... | CAS号75-16-1 甲基溴化镁 | CAS号3271-74-7 3β,5α-Dihydroxy...

3Beta-羟基-6-甲基-5,16-孕甾二烯-20-酮乙酸酯置于氢氧化钾,环己酮,Aluminum Isopropoxide,四氯苯醌体系中,用 甲醇,甲苯 作为反应溶剂,化学反应生成 美屈孕酮
参考文献:17烷基化孕酮系列的新合成与结构活性关系.
标题:17烷基化孕酮系列的新合成与结构活性关系.
摘要:
DOI:10.1021/jm00339A019

专利信息

专利号:US-11884714-B2
优先权日:2019-03-01
标 题:Cyclic peptide analogs of melanocortin and amanitin and methods of making such
发明人：PERRIN DAVID; TODOROVIC MIHAJLO; BÉNARD FRANÇOIS; ZHANG CHENGCHENG
权利人:UNIV BRITISH COLUMBIA; PROVINCIAL HEALTH SERVICES AUTHORITY
摘要:The invention described herein is based in part on the discovery of a protein/peptide crosslink, which introduces fluorescent properties, and which has been applied to synthesize analogues of melanocortin and amanitin as choice peptides to be explored in the context of isoindole peptides. Without limitation, it is expected that those trained in the art of peptide synthesis and stapling would appreciate the consequences of this invention such that other peptides of varied length can be similarly constrained by isoindole staples as featured herein.