CAS: 100481-09-2; Thiazole-2-Sulfonyl Chloride

相似化合物

459843-97-1 959997-70-7 1272357-53-5

上下游产品

CAS号288-47-1 噻唑 | CAS号109-72-8 正丁基锂 | CAS号5685-05-2 2-巯基噻唑 | CAS号3034-53-5 2-溴噻唑

2-巯基噻唑置于n-氯代丁二酰亚胺体系中,用 二氯甲烷,水 用作溶剂,化学反应 0.5H,反应生成2-噻唑磺酰氯
参考文献:异戊二醇的自由基芳基化反应合成8-芳基醇类特权化合物
标题:异戊二醇的自由基芳基化反应合成8-芳基醇类特权化合物
摘要:氢原子转移(hat)避免了廉价的单萜异胡薄荷醇的衍生化中不利的friedel-Crafts反应.各种易于制备的芳基和杂芳基磺酸盐经过正式的氢芳基化反应生成8-芳基薄荷醇,这是用于不对称合成的有优势的支架,以8-苯基薄荷醇为代表.在相关系统中观测到高立体选择性.Hat的这种使用极大地扩展了廉价的单萜异胡薄荷醇的手性库.
Doi:10.1021/acs.Orglett.6B01047

专利信息

专利号:US-8138272-B2
优先权日:2006-05-22
标 题:Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds
发明人：KONRADI ANDREI W; SMITH JENIFER L
权利人:KONRADI ANDREI W; SMITH JENIFER L; ELAN PHARM INC
摘要:This invention provides an improved synthesis of polymer conjugates of formula (I), n nof agricultural, therapeutic, and food additive compounds. In particular, a process is described for the preparation of conjugates by treating primary or secondary alcohol substituents of active compounds with polymeric nucleophiles using “Mitsunobuâ€? or related reaction conditions.

专利号:US-7211668-B2
优先权日:2003-07-28
标 题 :PNA monomer and precursor
发明人：KIM SUNG KEE; LEE HYUNIL; LIM JONG CHAN; LEE SUNG HEE
权利人:PANAGENE INC
摘要:This application relates to monomers of the general formula (I) for the preparation of PNA (peptide nucleic acid) oligomers and provides method for the synthesis of both predefined sequence PNA oligomers and random sequence PNA oligomers: n nwhereinn E is sulfur or oxygen; J is nitrogen or C—R′; R1, R′ is independently H, halogen, alkyl, nitro, nitrile, alkoxy, halogenated alkyl, halogenated alkoxy or a functional group having one of following general formulae: n nwhereinn A 1 , A 2 , A 3 , A 4 , A 5 , is independently selected from H, halogen such as F, Cl, Br or I, CF 3 , alkyl, preferably C 1 –C 4 alkyl, nitro, nitrile, alkoxy, preferably C 1 –C 4 alkoxy, halogenated (such as F, Cl, Br and I) alkyl, preferably halogenated C 1 –C 4 alkyl, halogenated (such as F, Cl, Br and I) alkoxy, preferably halogenated C 1 –C 4 alkoxy, phenyl, and halogenated (such as F, Cl, Br and I phenyl; R2 is H or protected or unprotected side chain of natural or unnatural α-amino acid; and B is a natural or unnatural nucleobase, wherein when said nucleobase has an exocyclic amino function, said function is protected by protecting group which is labile to acids but stable to weak to medium bases in the presence of thiol.

专利号:US-4629811-A
优先权日:1982-05-03
标 题:3-sulfonylamino-4-aminobenzophenone derivatives
发明人：DOMINIANNI SAMUEL J
权利人:LILLY CO ELI
摘要:A process is provided which produces 3-sulfonylamino-4-aminobenzophenone intermediates useful in the regiospecific synthesis of benzimidazole antiviral agents.

专利号:NO-318910-B1
优先权日:1998-12-23
标 题:Protease inhibitors, method of synthesis and use thereof, and pharmaceutical composition