专利号:US-7329767-B2 优先权日:2003-10-03 标 题:Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof 发明人:DEWIS MARK L; JOHN THUMPLASSERIL V; ECKERT MARKUS A; COLSTEE JAN HERMAN; DA COSTA NEIL C; PEI TAO 权利人:INT FLAVORS & FRAGRANCES INC 摘要:Described are mixtures of at least four of the alkadienamides defined according to the structure: n nwherein R represents C 1 -C 2 n-alkyl; R 1 is 2-methyl-1-propyl and R 2 is hydrogen, or R 1 and R 2 taken together is a moiety having the formulan n nwherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides ; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.
专利号:US-8007841-B2 优先权日:2003-10-03 标 题 :Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof 发明人:JOHN THUMPLASSERIL V; ECKERT MARKUS A; DEWIS MARK L; COLSTEE JAN HERMAN; DA COSTA NEIL C 权利人:INT FLAVORS & FRAGRANCES INC 摘要:Described are mixtures of at least four of the alkadienamides defined according to the structure: n nwherein R represents C 1 -C 2 n-alkyl; R 1 is 2-methyl-1-propyl and R 2 is hydrogen, or R 1 and R 2 taken together is a moiety having the formula —(CH 2 ) n —, wherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides ; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.
专利号:US-8362019-B2 优先权日:2008-02-01 标 题:Synthesis and anti-proliferative effect of substituted imidazo[4,5-b]pyrazine compounds 发明人:WINFIELD LEYTE L 权利人:SPELMAN COLLEGE; WINFIELD LEYTE L 摘要:This invention provides for compounds, compositions, and methods that involve anti-proliferative and anti-neoplastic activity in cancer cells. In particular, a series of benzimidazole, purine, imidazopyridine, and imidazopyrizine compounds having selected substitution patterns are disclosed, and the activity of various subject compounds is demonstrated. In particular, the disclosure provides for substituted imidazo[4,5-b]pyrazine compounds having the general formula n ntheir salts, pharmaceutical compositions, and methods of treatment using the subject compounds and compositions.
专利号:US-2813869-A 优先权日:1957-03-29 标 题 :Vapor phase synthesis of carbon-substituted pyrazines and piperazines 发明人:LANGDON WILLIAM K 权利人:WYANDOTTE CHEMICALS CORP
专利号:US-3113132-A 优先权日:1961-03-17 标 题:Synthesis of chlorinated alkylpyrazines 发明人:BAXTER GEORGE E; LEVIS JR WILLIAM W 权利人:WYANDOTTE CHEMICALS CORP
专利号:CN-1186329-C 优先权日:2003-08-01 标题:A method for catalyzing the synthesis of alkylpyrazine compounds with granular solid superacid