CAS: 2106-05-0; 5-Chloro-2-Fluoroaniline

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CAS号345-18-6 5-氯-2-氟硝基苯 | CAS号89-61-2 2,5-二氯硝基苯 | CAS号696-02-6 4-氯-1,2-二氟苯 | CAS号133117-00-7 2-chloro-1-(2-c... | CAS号1003575-43-6 3-氨基-4-氟苯硼酸频哪醇酯 | CAS号121872-94-4 2'-氯-4',5'-二氟苯乙酮 | CAS号110877-64-0 2-氯-4,5-二氟苯甲酸 | CAS号103942-82-1 8-chlorophenazi... | CAS号704-11-0 Benzenamine, 5-...

在 Sodium Tetrahydroborate,Copper(L) Chloride体系中,用 乙醇 用作溶剂,以28.8 Mg的收率获得5-氯-2-氟苯胺
参考文献:阴离子配体促进选择性的c-f键还原消除,使c(sp 2)-h氟化†
标题:阴离子配体促进选择性的c-f键还原消除,使c(sp 2)-h氟化†
摘要:报道了有关阴离子配体促进选择性c-h键氟化的详细机理研究.阴离子配体的作用已通过实验证据和dft计算得以阐明.此外,硝酸盐促进了c-f键的还原性消除,使得各种对称和不对称的偶氮苯能够选择性地进行c-h键氟化,从而获得各种邻氟苯胺.
Doi:10.1039/c9Cc07726J

专利信息

专利号:WO-2021260722-A1
优先权日:2020-06-21
标 题:Design, synthesis of novel oxyindole inhibitors of denv rna dependent rna polymerase
发明人：GUNDLA RAMBABU; ASTHANA SHAILENDRA; BHATTACHARYYA SANKAR; MADDIPATI VENKATANARAYANA CHOWDARY; MITTAL LOVIKA; KAUR JASKARAN; RAWAT YOGITA
权利人:TRANSLATIONAL HEALTH SCIENCE AND TECH INSTITUTE; GANDHI INSTITUTE OF TECH AND MANAGEMENT
摘要:The present invention is drawn to novel compounds of formula I, II and III, including any conformational isomeric form, salts and solvates for inhibition of DENV RNA dependent and RNA polymerase. The present invention also discloses a process of synthesis of the compounds, compositions comprising the said compounds and use of the compounds and treatment comprising the compounds of the present invention.

专利号:US-5646085-A
优先权日:1991-10-04
标题:Material based on tungsten carbide(s), catalyst and process useful for the hydrogenation of an aromatic nitro or nitroso derivative employing this catalyst
发明人：JACQUOT ROLAND; MERCIER CLAUDE
权利人:RHONE POULENC CHIMIE
摘要:The present invention relates to a process and a catalyst for hydrogenation of aromatic nitro or nitroso (nitrosated) compounds. The process, useful in hydrogenation, especially in the liquid phase, of compounds, nitroaromatic ones in particular, is defined in that the said compound is hydrogenated in the presence of tungsten carbide, the partial pressure of hydrogen being at least equal to two atmospheres (2x105 pascals). The process also has application to organic synthesis.

专利号:US-7405310-B2
优先权日:2001-03-05
标 题:Non-nucleoside reverse transcriptase inhibitors
发明人：LINDSTROM STEFAN; SAHLBERG CHRISTER; WALLBERG HANS; KALYANOV GENAIDY; ODEN LOURDES SALVADOR; NAESLUND LOTTA
权利人:MEDIVIR AB
摘要:This invention relates to non-nucleoside reverse transcriptase inhibitors active against HIV-1 and having an improved resistance and pharmacokinetic profile. The invention further relates to novel intermediates in the synthesis of such compounds and the use of the compounds in antiviral methods and compositions.

专利号:US-2008139558-A1
优先权日:2006-02-24
标题 :Quinolones useful as inducible nitric oxide synthase inhibitors
发明人：SMITH NICHOLAS D; ROPPE JEFFREY R; BONNEFOUS CELINE; PAYNE JOSEPH E; ZHUANG HUI; CHEN XIAOHONG; LINDSTROM ANDREW K; DURON SERGIO G; HASSIG CHRISTIAN A; NOBLE STEWART A
权利人:KALYPSYS INC
摘要:The present invention relates to novel quinolones of Formula I that inhibit inducible NOS synthase together with methods of synthesizing and using the compounds including methods for inhibiting or modulating nitric oxide synthesis and/or lowering nitric oxide levels in a patient by administering the compounds for the treatment of disease.

专利号:CN-101786980-A
优先权日:2010-03-31
标题:Synthesis method of isatin derivatives

专利号:CN-101786980-B
优先权日:2010-03-31
标题 :Synthesis method of isatin derivatives