CAS: 2818-66-8; 5-Amino-2-Mercaptobenzimidazole

上下游产品

2-巯基-5-硝基苯并咪唑 5-Nitro-2-Mercaptobenzimidazole 6325-91-3
1H-苯并咪唑-2-硫醇 Benzimidazol-2-Thiol 134469-07-1

2-巯基-5-硝基苯并咪唑置于盐酸,铁粉体系中,用 乙醇,水 用作溶剂,以80%的收率获得5-氨基-2-巯基苯并咪唑
参考文献:Diversified Synthesis Of Novel Quinoline And Dibenzo Thiazepine Derivatives Using Known Active Intermediates
标题:Diversified Synthesis Of Novel Quinoline And Dibenzo Thiazepine Derivatives Using Known Active Intermediates
摘要:新型药物的开发以控制常规药物治疗中抗药性感染是当今的需求.通过趋同合成法开发了少量与抗溃疡相关的衍生物.成功合成的衍生物包括二苯并噻嗪啶-吡啶(sln11-Sln15)和苯并咪唑-氢奎宁基衍生物(sln16-Sln20).在最终步骤中采用了微波,超声和常规技术进行耦合.有效的技术被识别为超声技术,主要体现在时间和产率上.报告的化合物通过元素分析和谱学研究(如1H,13C NMR和质谱)进行了结构表征.
Doi:10.14233/ajchem.2013.14818

专利信息

专利号:US-8927560-B2
优先权日:2010-12-06
标 题 :4-Aza-2, 3-didehydropodophyllotoxin compounds and process for the preparation thereof
发明人：AHMED KAMAL; PAIDAKULA SURESH; BANALA ASHWINI KUMAR; ADLA MALLAREDDY; PAPAGARI VENKAT REDDY; JAKI RASHEED TAMBOLI
权利人:AHMED KAMAL; PAIDAKULA SURESH; BANALA ASHWINI KUMAR; ADLA MALLAREDDY; PAPAGARI VENKAT REDDY; JAKI RASHEED TAMBOLI; COUNCIL SCIENT IND RES
摘要:The present invention provides 4-Aza-2,3-didehydropodophyllotoxin compound of general formula A (4a-4z and 4aa-4ae) as useful potential antitumour agents against human cancer cell lines. The present invention further provides a process for the synthesis of 4-Aza-2,3-didehydropodophyllotoxin compounds (4a-4z and 4aa-4ae).

专利号:JP-2011520873-A
优先权日:2008-06-12
标题 :Method for preparing intermediate compounds for the synthesis of anti-ulcer drugs

专利号:US-11124609-B2
优先权日:2016-08-05
标 题:Polymeric coatings for metal surfaces
发明人：LAWTON JOHN A
权利人:SEABOURNE SOLUTIONS LLC
摘要:Polymer compositions for coating of metal surfaces including moieties that interact with a metal atom in the metal surface and optionally containing antifoulant moieties. These polymer compositions provide lubricious coatings for medical devices, anticorrosion coatings for metal components, and antifoulant coatings for marine components such as propellers. The polymer composition is synthesized in a safe manner in which the synthesis components are added to a synthesis vat and there is no need for filtration or removal of waste materials in any step including the consumer use. As such this invention provides an environmentally sound approach to composition synthesis, formulation development, and consumer use.

专利号:WO-9102040-A1
优先权日:1989-08-04
标 题:Cyclodextrin labels for nucleic acid and biochemical analysis
发明人：KOSAK KENNETH M
权利人:KOSAK KENNETH M
摘要:This invention provides a method of qualitative and quantitative nucleic acid sequence analysis using luminescent cyclodextrin (CD), labels for dideoxy-nucleotide chain terminators and oligonucleotide primers. The CD labels are nonradioactive and detected in a ''black'' background, avoiding problems of fluorescence and allowing more sensitivity. Through formation of inclusion complexes with various fluorophores, the CD labels provide the versatility of different colored labels, with potentially higher signal efficiency in aqueous solutions. The CD labels have similar structures and thereby provide simplicity of synthesis and use, with more uniform chemical/physical properties, even with different colored labels. The invention is intended for high volume nucleic sequencing employing photomultipliers or charge-coupled device cameras for detection. Through the combination of these features, this invention provides advantages of speed, sensitivity, simplicity and versatility previously unknown or suggested in the art of nucleic acid sequence analysis.