CAS: 533-70-0; 2,4-Diiodoaniline

该化合物是一种有机化合物,其特点是存在两个碘原子和一个附于苯环的氨基组,该化合物具有二碘本苯基结构,其中碘替代组位于与氨基组相对的2和4个位置上,该物质一般在室温中是固体,可能根据其纯度和形态表现出多种颜色.碘原子的存在有助于其再活动,使其在各种化学合成中有用,特别是在制药和农用化学品生产中.该氨基组向该化合物传授基本特性,使其能够参与核细胞反应.此外,2,4-Diiodobenzenamine可能展示生物活动,可以探索其在药用化学中的潜在用途.在处理该化合物时,应当采取安全防范措施,因为含碘物质可能是危险的.

英文名称2,4-Diiodoaniline
中文名称2,4-二碘苯胺
IUPAC名称2,4-diiodoaniline
其它别名反式五氟壬基三嗪; Aniline, 2,4-Diiodo-
CAS编号533-70-0
MFCD编号:MFCD01851096
EINECS号:670-775-3
FDA UNII编号:NV2D8O2252
分子式:C6H5I2N
分子量:344.92
产品CID: 1518570
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
产品信息参考;;;
InChIKey: YJWGKXIQTRYZSH-UHFFFAOYSA-N
InChI=1S/C6H5I2N/c7-4-1-2-6(9)5(8)3-4/h1-3H,9H2…
计算化学: 氢键受体数1.0氢键供体数1.0可旋转键数0.0

MSDS等安全信息

GHS象形图
GHS符号GHS06;
注释: Skull and crossbones
危险类别急性毒性类别3(吸入)
急性毒性类别3(经皮)
急性毒性类别3(经口)
特定目标器官毒性 - 单次接触类别3
皮肤腐蚀/刺激类别2
严重眼刺激类别2
警示词Danger(危险)
危险描述H331 |吸入会中毒.
H311 |皮肤接触会中毒.
H301 |吞咽会中毒.
H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
防范说明P261-P280-P302+P352
危险品标志T+

欧盟法规

C&L通报

上下游产品

合成工艺路线路线简述

苯胺置于碘化铵,Trans-3,5-Dihydroperoxy-3,5-Dimethyl-1,2-Dioxolane体系中,用乙腈作为反应溶剂,化学反应 2.0H,以86%的收率获得产物2,4-二碘苯胺
参考文献:反式-3,5-二氢过氧-3,5-二甲基-1,2-二氧戊环促进的芳香族底物的区域选择性溴化和碘化
标题:反式-3,5-二氢过氧-3,5-二甲基-1,2-二氧戊环促进的芳香族底物的区域选择性溴化和碘化
摘要:研发了在反式-3,5-二氢过氧-3,5-二甲基-1,2-二氧戊环的促进下,溴化铵和碘化铵分别选择性和有效地溴化和碘化芳族化合物.温和的反应条件,高的选择性和产率以及高的反应速率是该合成方法的一些主要优点.
DOI:10.1007/s13738-011-0026-7

专利信息

专利号:US-12146028-B2
优先权日:2016-06-06
标题:Iodo-functionalized polymers as mass spectrometry calibrants with a mass-defect offset
发明人：GRAYSON SCOTT M
权利人:THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND; POLYMER FACTORY SWEDEN AB
摘要:The present invention discloses novel calibrants containing between 1 and 5 iodine atoms and methods of making them using linear polymers, hyperbranched polymers, and biological polymers (including but not limited to proteins and peptides.) Methods of using the calibrants are also disclosed, such as mass spectrometry. The novel calibrants disclosed herein have a more cost- and time-efficient synthesis than other calibrants.

专利号:CN-108144612-A
优先权日:2016-12-02
标题:A kind of cobalt-based catalyst for one-pot synthesis of carboxylate and its preparation and application

专利号:WO-2016113757-A1
优先权日:2015-01-15
标题:Novel recyclable iodinating agent and its applications
发明人：SWAMY VINCENT PAUL; DESHMUKH AMARSINH JAYAWANT; GORE PRANAV SOPAN; THULASIRAM HIREKODATHAKALLU V
权利人:COUNCIL SCIENT IND RES
摘要:The present invention provides a novel recyclable catalysts of formula A, [Formula A should be inserted here] wherein X is selected from the group consisting of [Formula should be inserted here] The present invention also provides a novel recyclable iodinating agent of formula I, II or III and a process for the synthesis thereof. [ Formula I, II & III should be inserted here] Further, the present invention provides a process of halogenation of amines and heterocyclic compounds by employing recyclable catalyst of formula (I).

专利号:CN-116836130-B
优先权日:2023-08-31
标题:A kind of synthesis method of 3,4-dihydrobenzothiadiazine compounds

专利号:CN-116836130-A
优先权日:2023-08-31
标题:A kind of synthesis method of 3,4-dihydrobenzothiadiazine compounds

专利号:CN-118930443-A
优先权日:2024-06-28
标题 :Synthesis method of trimebutine intermediate and trimebutine maleate