1-乙炔基环戊醇置于5%-Palladium/activated Carbon,氢气体系中,用 甲醇 用作溶剂,80.0 °C,3.0 Mpa 条件下,反应生成1-乙基环戊醇 参考文献: Ethers And Esters Of 1-Substituted Cycloalkanols For Use As Aroma Chemicals[fr] éthers Et Esters De Cycloalcanols Substitués En Position 1 Destinés à être Utilisés En Tant Que Produits Chimiques Aromatiques 标题: Ethers And Esters Of 1-Substituted Cycloalkanols For Use As Aroma Chemicals[fr] éthers Et Esters De Cycloalcanols Substitués En Position 1 Destinés à être Utilisés En Tant Que Produits Chimiques Aromatiques 摘要:本发明涉及使用1-取代环烷醇的醚或酯,或两种或两种以上的1-取代环烷醇的醚或酯的混合物,或其立体异构体,或两种或两种以上的其立体异构体作为香气化学品的用途;用于修改香味组合物的气味特性;以及含有1-取代环烷醇的醚或酯,或两种或两种以上的1-取代环烷醇的醚或酯的混合物,或其立体异构体,或两种或两种以上的其立体异构体的香气化学品组合物;以及制备香味组合物或修改香味组合物的气味特性的方法.该发明还涉及特定的1-取代环烷醇的醚或酯.
专利号:US-7399806-B2 优先权日:2003-06-26 标 题:Synthesis of photoresist polymers 发明人:BENOIT DIDIER; SAFIR ADAM; CHANG HAN-TING; CHARMOT DOMINIQUE; OKAMOTO KENJI; NISHIMURA ISAO; WANG YONG 权利人:SYMYX TECHNOLOGIES INC 摘要:The present invention is directed to the preparation of photoresist polymers via living free radical polymerization techniques. Sterically bulky ester monomers are utilized as the polymerization components. Use of chain transfer agents is included in polymerization processing conditions. Cleavage of polymer terminal end groups that include a heteroatom are described.
专利号:US-7847092-B2 优先权日:2004-12-15 标题:Method for preparation of F-18 containing organofluoro compounds in alcohol solvents 发明人:MOON DAE HYUK; CHI DAE YOON; KIM DONG WOOK; OH SEUNG JUN; RYU JIN-SOOK 权利人:FUTURECHEM CO LTD; ASAN FOUNDATION 摘要:The present invention relates to a method for preparation of organofluoro compounds containing radioactive isotope fluorine-18. More particularly, the present invention relates to a method for preparation of primary or secondary organofluoro compound by reacting fluorine salt containing radioactive isotope fluorine-18 with primary or secondary alkyl halide or primary or secondary alkyl sulfonate in the presence of alcohol of Chemical Formula 1 as a solvent to obtain high yield of organofluoro compound. Synthesis reaction according to the present invention may be carried out under mild condition to give high yield of the organofluoro compounds and the reaction time is decreased, and thereby is suitable for the mass production of the organofluoro compounds.
专利号:CN-104470547-B 优先权日:2012-05-24 标题 :Utilize the method for tubular article synthesis of radiopharmaceuticals
专利号:US-5863950-A 优先权日:1993-01-15 标 题:HIV protease inhibitors 发明人:REICH SIEGFRIED H; LEWIS KATHLEEN; MELNICK MICHAEL; FUHRY MARY ANN M; KALDOR STEPHEN WARREN 权利人:AGOURON PHARMA 摘要:PCT No. PCT/US94/00419 Sec. 371 Date Oct. 27, 1994 Sec. 102(e) Date Oct. 27, 1994 PCT Filed Jan. 18, 1994 PCT Pub. No. WO94/15608 PCT Pub. Date Jul. 21, 1994HIV protease inhibitors, obtainable by chemical synthesis, block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and possibly other anti-viral agents as ingredients, are thus suitable for the treatment of the HIV virus known to cause AIDS.
专利号:CN-117466733-A 优先权日:2023-09-13 标题 :A kind of synthesis method of acid-catalyzed cycloalkane methacrylate
专利号:US-9550704-B2 优先权日:2012-05-24 标 题 :Method for synthesizing radiopharmaceuticals using a cartridge 发明人:CHI DAE YOON; LEE BYOUNG SE; LEE JAE HAK; CHU SO YOUNG; JUNG WOON JUNG 权利人:FUTURECHEM CO LTD 摘要:The present invention relates to a method for synthesizing a radiopharmaceutical using a cartridge, which makes it possible to carry out several steps of reaction required for synthesizing a radiopharmaceutical in the cartridge filled with a polymer. A method for synthesizing a radiopharmaceutical according to the present invention enables each step's reaction to be carried out with the solution confined in the cartridge so as not to flow out, thus being simplified compared to the conventional methods for synthesizing radiopharmaceuticals, and expediting the synthesis thereof.
参考文献:10.1007/bf00957360 摘要:Dorofeenko GN, Zhdanov YA, Étmetchenko LN. Synthesis of pyrylium salts and pyridine bases by the bisacylation of cyclic tertiary alcohols. Chemistry of Heterocyclic Compounds. 1969 Sep;5(5):576–9. doi: 10.1007/bf00957360. 参考文献:10.1023/b:rucb.0000024841.74897.c2 摘要:Dzhemilev UM, Ibragimov AG, Khafizova LO, Gilyazev RR, D"yakonov VA. Synthesis and transformations of metallacycles. 32. Novel method for the synthesis of cyclopentanols from aluminacyclopentanes. Russian Chemical Bulletin. 2004 Jan;53(1):133–6. doi: 10.1023/b:rucb.0000024841.74897.c2.