CAS: 155-84-0; Ac-Arg-Oh

相似化合物

35436-73-8 210545-23-6 2389-86-8

上下游产品

L-arginine hydr°Chloride acetic anhydride Fm°C-L-Arg-OH acetic acidN-Acetyl-arginin-methylamid R-(-)-(1-(2)H)agmatine sulfate L-arginine

在 氨体系中,用 甲醇 用作溶剂,化学反应生成N-α-乙酰-L-精氨酸
参考文献:硝基精氨酸和含硝基精氨酸的肽的氨解;一些副反应
标题:硝基精氨酸和含硝基精氨酸的肽的氨解;一些副反应
摘要:含硝基精氨酸的肽的氨解导致含鸟氨酸的副产物的形成.这些副产物的结构已从模型实验中推导出来.这种副反应可通过使用n,可以避免ģ甲苯磺酰基,或者n ģ-Dicarbobenzoxy保护基团.
Doi:10.1002/hlca.19740570310

专利信息

专利号:WO-2023222057-A1
优先权日:2022-05-19
标 题 :Method for preparing self-assembling peptide rada16 by means of solid phase convergent synthesis
发明人：CHEN HONGYU; CHEN JINGSHUN; BI YAPING; LU JINGJING
权利人:JIANGSU AOSAIKANG PHARM CO LTD; NANJING HAIRUN PHARMACEUTICAL CO LTD
摘要:The present invention relates to the field of polypeptide synthesis, and provides a method for preparing a self-assembling peptide RADA16 by means of solid phase convergent synthesis. According to the present invention, a peptide fragment and a peptide resin are prepared by means of a solid-phase synthesis method, and the peptide fragment and the peptide resin are coupled to obtain a self-assembling peptide RADA16. According to the present invention, the purity of the prepared RADA16 crude product can reach 80% or more, and the method reduces the difficulty of separation and purification, is easy to operate, and uses readily available raw materials.

专利号:JP-H06507378-A
优先权日:1990-11-21
标题:Synthesis of equimolar mixtures of oligomers, especially mixtures of oligopeptides

专利号:US-11408897-B2
优先权日:2015-10-14
标 题:Mass defect-based multiplex dimethyl pyrimidinyl ornithine (DiPyrO) tags for high-throughput quantitative proteomics and peptidomics
发明人：LI LINGJUN; FROST DUSTIN; BUCHBERGER JONES AMANDA
权利人:WISCONSIN ALUMNI RES FOUND
摘要:The use of mass defect signatures to impart milliDalton mass differences between isotopically labeled peptides at the MS1-level allows multiplex quantification without the increased mass spectral complexity that occurs with mass difference approaches. Provided herein is a mass defect-based chemical tag, dimethyl pyrimidinyl ornithine (DiPyrO), that is compact and easy to synthesize at high purity in few steps using commercially available starting materials. The multiplex DiPyrO tags are amine-reactive and can impart a mass difference onto labeled peptides and through calculated substitution of heavy isotopes. DiPyrO offers up to 10-plex quantification on current Orbitrap or FT-ICR platforms without increasing mass spectral complexity. The synthesis of the DiPyrO tag is provided along with viability of the DiPyrO tag for labeling complex proteomics samples using yeast extract digests and its effect on labeled peptides during LC-MS2 analysis. Labeling and quantification of glycans and metabolites using the DiPyrO tag is also demonstrated.

专利号:WO-9209300-A1
优先权日:1990-11-21
标 题:Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures

专利号:EP-0558671-A4
优先权日:1990-11-21
标题 :Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures

专利号:EP-0558671-A1
优先权日:1990-11-21
标 题 :Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures