CAS: 2508-29-4; 5-Amino-1-Pentanol

相似化合物

75178-90-4 209115-33-3 87905-98-4

上下游产品

CAS号111-29-5 1,5-戊二醇 | CAS号4221-03-8 5-羟基戊醛 | CAS号75178-90-4 5-(叔丁氧羰氨基)-1-戊醇 | CAS号1039627-20-7 N-(pent-4-en-1-... | CAS号110-86-1 吡啶 | CAS号675-20-7 2-氮己环酮 | CAS号4795-29-3 2-四氢糠胺 | CAS号1745-60-4 5-chloropentan-... | CAS号59578-63-1 4-苯甲氨基-1-丁醇 | CAS号142342-55-0 5-b°C-氨基戊基甲烷磺酸酯 | CAS号143248-37-7 2-hydroxy-N-(5-... | CAS号194213-77-9 5-(2,6-dipyridi... | CAS号194225-78-0 benzyl N-(5-iod... | CAS号209115-33-3 9H-芴-9-基甲基(5-羟基... | CAS号191417-53-5 5-(anthracen-9-... | CAS号626-67-5 1-甲基哌啶 | CAS号84-26-4 吴茱萸次碱 | CAS号675-20-7 2-氮己环酮

1,5-戊二醇置于[ruhcl(Co)(Pph3)3],1,1,1-Tris(Diethylphosphinomethyl)Ethane 氨体系中,用 甲苯 用作溶剂,155.0 °C,4.0 Mpa 条件下,反应 12.0H,反应生成5-氨基-1-戊醇
参考文献:Process For Preparing Alkanolamines By Homogeneously Catalyzed Alcohol Amination
标题:Process For Preparing Alkanolamines By Homogeneously Catalyzed Alcohol Amination
摘要:通过使用氨和消除水的方式,通过醇胺化二醇制备具有一元氨基(-nh2)和一个羟基(-oh)的烷基胺的过程,其中反应在至少含有来自周期表第8,9和10族的至少一种元素以及至少一种给体配体的复合催化剂存在下均相催化进行.

专利信息

专利号:US-6531591-B1
优先权日:1999-07-07
标 题 :Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates
发明人：FENSHOLDT JEF
权利人:EXIQON AS
摘要:Quinone phosphoramidite reagents as well as photoreactive ketone phosphoramidite reagents, such as anthraquinone phosphoramidite reagents and benzophenone phosphoramidite reagents were synthesized and used for the solid phase synthesis of photoreactive-oligonucleotide conjugates. These phosphoramidite reagents are stable, suitable for large-scale synthesis and designed for automated solid phase synthesis of oligomers terminating in a photoreactive moiety.

专利号:EP-1202998-B1
优先权日:1999-07-07
标 题 :Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates
发明人：FENSHOLDT JEF
权利人:EXIQON AS
摘要:Quinone phosphoramidite reagents as well as photoreactive ketone phosphoramidite reagents, such as anthraquinone phosphoramidite reagents and benzophenone phosphoramidite reagents were synthesized and used for the solid phase synthesis of photoreactive-oligonucleotide conjugates. These phosphoramidite reagents are stable, suitable for large-scale synthesis and designed for automated solid phase synthesis of oligomers terminating in a photoreactive moiety.

专利号:US-6872727-B1
优先权日:1999-08-26
标 题:Polycyclic pyrimidine -2,4(1H,3H)-diones with functionalized alkyl residues at the 1- and/or 3-position(s); methods for their synthesis and pharmaceutical preparation
发明人：HERRMANN KONRAD; LEISTNER SIEGFRIED; WIPPICH PETRA
权利人:PRIVATES INST FUR BIOMEDIZINIS
摘要:Polycyclic pyrimidine-2,4(1H,3H)-diones with functionalized alkyl residues at the 1-, the 3-, or both position(s); methods for their synthesis, production, and pharmaceutical preparation. The invention concerns the synthesis of the above-described compounds, their chemical and structural characterization, and the analysis of their physiological/pharmacological activities in vitro and in vivo. These goals have been attained by the specification of routes of synthesis, methods for the production of the compounds, and the presentation of compound-specific characteristics. The substances encompassed by the present invention demonstrate pharmacologically significant collangenase/matrix metalloproteinase inhibitory activities. The specific example 1-(3-mercaptoprop-1-yl)-3-methyl-chinazolin-2,4(1H,3H)-dione will be presented in detail.

专利号:US-2025129021-A1
优先权日:2023-09-19
标 题:Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I), Formula (V)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:US-2004014168-A1
优先权日:1998-06-11
标题:Reagents and methods for library synthesis and screening
发明人：SCHREIBER STUART L; BLACKWELL HELEN E; PEREZ FERNANDEZ LUCY; TALLARICO JOHN A
权利人:HUGHES HOWARD MED INST
摘要:The invention provides novel solid supports for the synthesis of compound libraries. The solid supports have the physical capacity to deliver at least 50 nmol of compound and are functionalized with a silicon-containing linker. In one embodiment of the invention the solid support comprises a bead having a diameter of between approximately 400 and 600 μm functionalized with a silicon-containing linker. According to certain embodiments of the invention the bead is a polystyrene bead. According to certain embodiments of the invention the linker is a diisopropylalkyl-substituted silyl ether. The invention further provides grafted polymeric supports such as lanterns functionalized with a silicon-containing linker. n The invention provides methods for screening in which compounds are synthesized on solid supports in a quantity so that a single solid support such as a bead provides a stock solution sufficient to perform hundreds or thousands of biological or chemical assays. The methods include decoding the sequence of chemical reactions used to synthesize the compound by identifying tags incorporated into the compound during synthesis.

专利号:US-2024199566-A1
优先权日:2022-11-16
标题:Catalytic synthesis of delta-valerolactone (dvl) from furfural-derived 2-hydroxytetrahydropyran (hthp)
发明人：HUBER GEORGE; DASTIDAR RAKA; JOHNSTONE SAM; MCCLELLAND DANIEL
权利人:WISCONSIN ALUMNI RES FOUND
摘要:A method to make delta-valerolactone (“DVLâ€?) by dehydrogenating 2-hydroxytetrahydropyran (“HTHPâ€?). The HTHP is contacted with a supported-metal catalyst for a time, at a temperature, and at a pressure wherein at least a portion of the HTHP is converted to DVL via dehydrogenation of the HTHP. The HTHP may be derived from biomass. Thus, the method yields DVL without requiring a petroleum-based feedstock.