CAS: 63283-36-3; (S,Z)-3-((E)-2-((1R,3As,7Ar)-1-((R)-6-Hydroxy-6-Methylheptan-2-yl)-7A-Methylhexahydro-1H-Inden-4(2H)-Ylidene)Ethylidene)-4-Methylenecyclohexanol Hydrate

专利信息

专利号:WO-2022101282-A1
优先权日:2020-11-13
标 题 :Synthesis of 25-hydroxy-vitamin d3, 25-hydroxy-7-dehydrocholesterol and analogous alcohols using the beta-proteobacterium thauera aromatica
发明人：BOLL MATTHIAS; JACOBY CHRISTIAN
权利人:UNIV FREIBURG ALBERT LUDWIGS
摘要:The present invention relates to methods using recombinant Thauera aromatica cells to produce oxygen-independent molybdenum-hydroxylases in order to convert vitamin D 3 , 7-dehydrocholesterol and related alkylated compounds into 25-hydroxy-vitamin D 3 , 25- hydroxy-7-dehydrocholesterol and analogous alcohols. The underlying biocatalytic method links the water-dependent hydroxylation of alkyl residues with the nitrate- reducing respiratory chain of the strain as electron acceptor system. In contrast to commonly used methods, the present method does no longer require the artificial regeneration of the electron-carrier.

专利号:US-10335382-B2
优先权日:2013-06-14
标 题:Use of hydrogen sulfide synthesis inhibitors for cancer therapy
发明人：HELLMICH MARK; ZHOU JIA; SZABO CSABA
权利人:HELLMICH MARK; ZHOU JIA; SZABO CSABA; UNIV TEXAS
摘要:In certain aspects the methods comprise administering an inhibitor of hydrogen sulfide biosynthesis, a cystathionine-β-synthase (CBS) inhibitor, or a hydrogen sulfide neutralizing agent to a patient having a cancer associated with elevated production of hydrogen sulfide.

专利号:EP-4001424-A1
优先权日:2020-11-13
标题:Synthesis of 25-hydroxy-vitamin d3, 25-hydroxy-7-dehydrocholesterol and analogous alcohols using the beta-proteobacterium thauera aromatica

专利号:US-2019336462-A1
优先权日:2013-06-14
标题 :Use of hydrogen sulfide synthesis inhibitors for cancer therapy

专利号:US-2016095831-A1
优先权日:2013-06-14
标 题:Use of hydrogen sulfide synthesis inhibitors for cancer therapy