CAS: 113893-08-6; Benzo[b]Thiophen-3-Ylboronic Acid

相似化合物

171364-86-6 177735-30-7 628692-17-1

上下游产品

CAS号7342-82-7 3-溴苯并噻吩 | CAS号5419-55-6 硼酸三异丙酯

苯并噻吩置于三苯基硼烷体系中,用 二氯甲烷,水 用作溶剂,化学反应 0.5H,反应生成苯并噻吩-3-硼酸
参考文献:一种苯并杂环-3-硼酸的制备方法
标题:一种苯并杂环-3-硼酸的制备方法
摘要:本发明公开了一种苯并杂环‑3‑硼酸的制备方法,属于有机硼酸化学技术领域.从苯并杂环出发,在催化剂存在下,与三卤化硼选择性付克反应,水解后得到苯并杂环‑3‑硼酸.本发明中通过选择合适的催化剂和反应条件,通过高选择性在杂环3位进行定位,水解后得到硼酸,利用2位和3位硼酸性质的差异,经过纯化后得到苯并杂环‑3‑硼酸.该方法为苯并杂环‑3‑硼酸提供了较为简洁的合成路径,收率较高,异构体纯化较为容易.

专利信息

专利号:US-9370515-B2
优先权日:2013-03-07
标题 :Mixed lineage kinase inhibitors and method of treatments
发明人：GOODFELLOW VAL S; NGUYEN THONG X; RAVULA SATHEESH B; GELBARD HARRIS A
权利人:CALIFIA BIO INC; UNIV ROCHESTER
摘要:Provided herein are imidazopyridine compounds having an inhibitory effect on mixed lineage kinases (MLKs), methods of their synthesis, and methods of their therapeutic. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and pharmaceutical compositions.

专利号:US-2009137566-A1
优先权日:2005-05-26
标 题 :Substituted Piperdines as Renin Inhibitors
发明人：EHARA TAKERU; HITOMI YUKO; KONISHI KAZUHIDE; MASUYA KELICHI
权利人:EHARA TAKERU; HITOMI YUKO; KONISHI KAZUHIDE; MASUYA KELICHI
摘要:The invention relates to substituted 3,4- or higher substituted piperididine compounds, the use thereof for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; pharmaceutical formulations or products comprising said compounds, and/or a method of treatment comprising administering said compounds, a method for the manufacture of said compounds, as well as novel intermediates, starting materials and/or partial steps for their synthesis. The compounds preferably have the formula I, n n n n n n n n n n wherein the moieties R1, R2, R11 and W are as defined in the specification.

专利号:US-2009137557-A1
优先权日:2005-11-22
标题 :Calcilytic Compounds
发明人：KU THOMAS WEN FU; LIN HONG; LUENGO JUAN I; MARQUIS JR ROBERT W; RAMANJULU JOSHI M; TROUT ROBERT; YAMASHITA DENNIS S
权利人:KU THOMAS WEN FU; LIN HONG; LUENGO JUAN I; MARQUIS JR ROBERT W; RAMANJULU JOSHI M; TROUT ROBERT; YAMASHITA DENNIS S
摘要:Novel calcilytic compounds, pharmaceutical compositions, methods of synthesis and methods of using them are provided.

专利号:CN-118164909-A
优先权日:2024-04-22
标 题:Synthesis method of non-activated olefin selective arylation

专利号:CN-114835625-A
优先权日:2022-06-23
标 题 :A kind of axial chiral indole derivatives containing 2-thiocyano-3-aryl group synthesis method