CAS: 128008-30-0; Indium(Iii) Trifluoromethanesulfonate

相似化合物

74974-60-0 2926-30-9 144026-79-9

专利信息

专利号:US-2024116890-A1
优先权日:2022-09-28
标 题 :Large scale synthesis of cannabinol
发明人：COLLINS ARIANNA C; CRUCES IVAN; RAY KYLE; CRUCES WESTLEY
权利人:COLORADO CHROMATOGRAPY LLC
摘要:Methods for producing cannabinol, cannabivarin, or derivatives thereof are disclosed. The methods disclosed herein can be employed for large scale synthesis or semi-synthesis of the compounds, including multi-kilogram quantities of the compounds.

专利号:US-12331007-B2
优先权日:2021-10-15
标题 :Use of a multidentate phosphite ligand in the catalytic synthesis of adiponitrile
发明人：CHEN ZHIRONG; WU WENBIN; YIN HONG; ZHA ZENGSHI; WANG KEYAN; MA LI; HUANG GUODONG; ZHOU GUIYANG; XU YONG
权利人:ZHEJIANG NHU CO LTD; ZHEJIANG NHU SPECIAL MAT CO LTD; ZHEJIANG NHU NYLON MAT CO LTD
摘要:A multidentate phosphite ligand is used in the catalytic synthesis of adiponitrile. The ligand is represented by the following general formula (I). The method of catalytic synthesis of adiponitrile comprises primary hydrocyanation, isomerization, and secondary hydrocyanation reactions, wherein the catalyst adopted each comprises a phosphite ligand-nickel complex composed of a nickel precursor and a multidentate phosphite ligand. The ligand molecule has a higher electron cloud density, and the phosphorus content capable of participating in coordination in the ligand molecule per unit mass is higher, so that the catalytic activity of the catalyst is improved, and the amount of the catalyst is reduced.

专利号:US-10155772-B2
优先权日:2010-07-08
标题:Process for the synthesis of substituted morphinans
发明人：DUNCAN SCOTT
权利人:ALKERMES PHARMA IRELAND LTD
摘要:The invention further relates to a process for the synthesis of 3-carboxamide substituted morphinans where a 3-cyano substituted 6-oxo substituted morphinan is reacted with a 1,3-diol.

专利号:US-2025091989-A1
优先权日:2023-09-19
标 题 :Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:WO-2012089181-A1
优先权日:2010-12-30
标题 :O-substituted (2r,3r)-3-(3-hydroxyphenyl)-2-methyl-4-pentenoic acids and a method of obtaining the same
发明人：VLASAKOVA RUZENA; HAJICEK JOSEF; ZEZULA JOSEF
权利人:ZENTIVA KS; VLASAKOVA RUZENA; HAJICEK JOSEF; ZEZULA JOSEF
摘要:The compounds of general formula II are new and represent important intermediates in the synthesis of tapentadol. In the synthesis of tapentadol of formula I and its pharmaceutically acceptable salts, O-protected (2R,3R)-acids of general formula II, in step A, are reacted in an inert organic solvent with an activating agent, optionally in presence of a catalyst or a base; in step B, the obtained compounds of general formula V, wherein R has the above mentioned meaning and X stands for chlorine or alkoxycarbonyloxyl group O-CO-OR 1 or pivaloyloxyl O-CO-t-Bu group, wherein R 1 is methyl or ethyl, are reacted with dimethylamine or its salts optionally in presence of a base; in step C, the obtained N, N-dimethylamides of general formula VI, wherein R has the above mentioned meaning, are reduced by means of hydride agents in a suitable solvent; in step D, the produced alkeneamines of general formula VII, wherein R has the above mentioned meaning, are hydrogenated on a metal catalysts in a suitable solvent; and, finally, in step E, the produced alkaneamines of general formula VIII, wherein R has the above mentioned meaning, are O-dealkylated by means of dealkylating agents, and, if required, the obtained tapentadol is converted by the action of a pharmaceutically acceptable acid to respective salts, e.g. hydrochloride.

专利号:WO-2017030685-A1
优先权日:2015-08-14
标题 :One-pot synthesis of anhydropentitol mono- and diethers
发明人：STENSRUD KENNETH
权利人:ARCHER DANIELS MIDLAND CO
摘要:A process for preparing anhydropentitol mono- and diethers from C 5 sugar alcohols is described. The process involves performing in a single reaction vessel consolidated reactions that a) cyclize dehydratively a linear C 5 sugar alcohol and b) etherify a resulting anhydropentitol. Each of the reactions is catalyzed by a very low amount of a water-tolerant Lewis acid catalyst relative to the starting sugar-alcohol. Depending on the reaction conditions, the synthesis method is efficient, selective and affords good yields of mono- and diethers. The anhydropentiol ethers can serve as renewable substitute precursors of petroleum incumbents for use in the making of surfactants and plasticizers.