CAS: 383-63-1; Ethyl Trifluoroacetate

上下游产品

CAS号75934-34-8 N-(2,2-diethoxy... | CAS号74-84-0 乙烷 | CAS号407-25-0 三氟乙酸酐(TFAH) | CAS号64-17-5 乙醇 | CAS号76-05-1 三氟乙酸(TFA) | CAS号75934-36-0 N-(2,2-diethoxy... | CAS号60-29-7 乙醚 | CAS号68602-57-3 三氟乙酰三氟甲磺酸酯 | CAS号93749-47-4 4-(2,2-二乙氧基乙氧基)苯甲酸甲酯 | CAS号10556-91-9 4,4,4-三氟-2-丙基-3... | CAS号104863-72-1 Ethanone, 1-(1,... | CAS号105439-85-8 1,1,1-trifluoro... | CAS号332-34-3 2,2,2-三氟-4’-甲氧基乙酰苯胺 | CAS号33284-21-8 3-三氟乙酰基吡啶 | CAS号507-52-8 2-三氟甲基-2-丙醇 | CAS号421-50-1 1,1,1-三氟丙酮(TFK) | CAS号400-54-4 1,1,1-三氟-2,4-己二酮 | CAS号360-92-9 N,N-二乙基-2,2,2-三氟乙酰胺 | CAS号387-89-3 2-(三氟乙酰基)环己酮

1-乙氧基-2,2,2-三氟乙醇置于potassium Hydrogensulfate,2,2,6,6-四甲基哌啶氧化物,Sodium Hypochlorite Pentahydrate体系中,用 氘代乙腈 作为反应溶剂,化学反应 1.0H,以77%的收率获得产物三氟乙酸乙酯
参考文献:次氯酸钠五水合物氧化氟代烷基醇[1]
标题:次氯酸钠五水合物氧化氟代烷基醇[1]
摘要:通过在酸和硝基氧基自由基催化剂存在下,与次氯酸钠五水合物在乙腈中反应,将氟代烷基醇有效地氧化为相应的氟代烷基羰基化合物.尽管在无硝氧基自由基催化剂的条件下反应进行得较慢,但仍以高收率获得了所需的羰基化合物.为了与氟代烷基烯丙基醇反应,以高收率获得了相应的α,β-环氧酮水合物.
DOI:10.1016/j.Jfluchem.2020.109719

专利信息

专利号:US-2022298204-A1
优先权日:2019-07-05
标题 :Synthesis of a-amanitin and its derivatives
发明人：SIEGERT MARY-ANN; KNITTEL CAROLINE HERTA; SÃœSSMUTH RODERICH
权利人:PURE BIOORGANICS SIA
摘要:The present invention relates to the chemical synthesis of α-amanitin and its derivatives. The present invention also relates to intermediate products of the α-amanitin synthesis.

专利号:US-2006264608-A1
优先权日:2001-08-03
标题 :Bi-directional synthesis of oligoguanidine transport agents
发明人：WENDER PAUL A; VANDEUSEN CHRISTOPHER L; PATTABIRAMAN KANAKA; PELKEY ERIN T; JESSOP THEODORE C
权利人:WENDER PAUL A; VANDEUSEN CHRISTOPHER L; PATTABIRAMAN KANAKA; PELKEY ERIN T; JESSOP THEODORE C
摘要:Synthesis routes that can be adapted to large scale synthesis of oligoguanidine compounds such as oligoarginine compounds are described which use a perguanidinylation step to convert a group of ω-amino groups to the corresponding guanidinyl groups. These compounds find utility as transport agents. Modified oligoguanidine compounds are also described.

专利号:US-8058414-B2
优先权日:2008-04-29
标题 :Unnatural polymerase substrates that can sustain enzymatic synthesis of double stranded nucleic acids from a nucleic acid template and methods of use
发明人：MENCHEN STEVEN; ROSENBLUM BARNETT; KENNEY PAUL; KHAN SHOEB; MA ZHAOCHUN; CHEN JER-KANG; LAM JOE Y; HUANG BOLI
权利人:MENCHEN STEVEN; ROSENBLUM BARNETT; KENNEY PAUL; KHAN SHOEB; MA ZHAOCHUN; CHEN JER-KANG; LAM JOE Y; HUANG BOLI; LIFE TECHNOLOGIES CORP
摘要:Nucleotide analogs that can sustain the enzymatic synthesis of double-stranded nucleic acid from a nucleic template are described. The nucleotide analogs include: (i) a base selected from the group consisting of adenine, guanine, cytosine, thymine, uracil and their analogs; (ii) a label attached to the base or analog of the base via a cleavable linker; (iii) a deoxyribose; and (iv) one or more phosphate groups. The linker and/or the label inhibits template directed polymerase incorporation of a further nucleotide substrate onto an extended primer strand. In addition, cleavage of the linker leaves a residue attached to the base which is not present in the natural nucleotide and which does not inhibit extension of the primer strand. The nucleotide analogs can therefore be used as reversible terminators in sequencing by synthesis methods without blocking the 3′ hydroxyl group. Methods of sequencing DNA using the substrates are also described.

专利号:US-7705136-B2
优先权日:2005-02-25
标 题 :Synthesis of 3′-, or 5′-, or internal methacrylamido-modified oligonucleotides
发明人：GOLOVA JULIA B; CHERNOV BORIS K
权利人:UCHICAGO ARGONNE LLC
摘要:New modifiers were synthesized for incorporation of a methacrylic function in 3′-, 5′- and internal positions of oligonucleotides during solid phase synthesis. A modifier was used for synthesis of 5′-methacrylated oligonucleotides for preparation of microarrays by a co-polymerization method.

专利号:US-6252105-B1
优先权日:1998-07-06
标题:Synthesis of low-fluoride organic compounds
发明人：BRAUN MAX; EICHER JOHANNES; JANSSENS FRANCINE; EICHHOLZ KERSTIN; PALSHERM STEFAN
权利人:SOLVAY FLUOR & DERIVATE
摘要:Organic compounds, e.g. fluorinated organic compounds such as fluorinated carboxylic acids or fluorinated carboxylic acid chlorides, may contain small amounts of carboxylic acid fluorides, hydrogen fluoride or hydrolyzable fluoride, which during the preparation of derivatives of the fluorinated organic compounds, for example by esterification, may yield corrosive fluorides or hydrogen fluoride. The invention is a method for the synthesis and/or purification of preferably fluorinated organic compounds such as carboxylic acids, carboxylic acid chlorides and derivatives such as esters thereof, starting from corresponding carboxylic acid chlorides containing acid fluorides or hydrolyzable fluoride, and alcohols under the catalytic action of 'onium' salts of carboxylic acids, to obtain products which have a low fluoride content. Alternatively, an inorganic oxide adsorbent is utilized. The method is especially suitable for the synthesis of esters of trifluoroacetic acid, chlorodifluoroacetic acid, trifluoroacetoacetic acid and/or difluoroacetoacetic acid.

专利号:US-5763587-A
优先权日:1987-11-27
标题:Process for the synthesis of amikacin
发明人：MANGIA ALBERTO
权利人:GIST BROCADES ITALY SPA
摘要:In the synthesis of amikacin, having the formula: (I) by acylation of a diprotected derivative of kanamycin A with a reactive derivative of L-(-)-4-amino-2-hydroxybutyric acid, the selection of the reaction solvent and of the pH conditions permit the industrial economically and the synthesis yield to be improved.