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glycerol epichlorohydrin2-aminoethyl 2,3-dihydroxypropyl hydrogen phosphate海关参考信息
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专利信息
专利号:US-4078331-A
优先权日:1976-04-28
标题:Process and culture composition for growth of alga and synthesis of biopolymer
发明人:SAVINS JOSEPH GEORGE; PAUL JAMES M
权利人:MOBIL OIL CORP
摘要:This specification discloses a process and a culture composition for growth of an alga and synthesis of biopolymer by the alga. The process involves growth of the alga and concomitant synthesis of the biopolymer in an aqueous culture containing as a source of phosphate for said alga dibasic sodium or dibasic potassium phosphate. The nitrogen source can be sodium nitrate or urea. Control of the pH of the culture is effected by injecting a mixture of carbon dioxide and air into the culture during growth of the alga and synthesis of the biopolymer. The carbon dioxide also serves as a source of carbon for growth of the alga and synthesis of the biopolymer and provides agitation/mixing within the culture chamber. Preferably, the mixture of carbon dioxide and air is injected continuously into the culture during the entire growth period of the alga.
专利号:US-2013040990-A1
优先权日:2010-02-02
标题 :SYNTHESIS OF DGJNAc FROM D-GLUCURONOLACTONE AND USE TO INHIBIT ALPHA-N-ACETYLGALACTOSAMINIDASES
发明人:FLEET GEORGE WILLIAM JOHN; BUTTERS TERRY DOUGLAS
权利人:UNIV OXFORD; FLEET GEORGE WILLIAM JOHN; BUTTERS TERRY DOUGLAS
摘要:A convenient and scalable synthesis of DGJNAc ID from D-glucuronolactone in an overall yield of 20% is provided. DGJNAc is the first highly potent and specific competitive inhibitor of GalNAcases. DGJNAc ID is also a competitive inhibitor of -hexosaminidases. Synthesis and activity of L-DGJNAc IL is also shown. The use of DGJNAc as a potent and specific inhibitor of GalNAcases will allow useful investigation and treatment of a number of diseases, including Schindler Disease.
专利号:US-8314209-B2
优先权日:2007-12-12
标 题 :Lipid-assisted synthesis of polymer compounds and methods for their use
发明人:RAJAMANI SUDHA; OLASAGASTI FELIX; DEAMER DAVID W; BENNER SEICO
权利人:RAJAMANI SUDHA; OLASAGASTI FELIX; DEAMER DAVID W; BENNER SEICO; UNIV CALIFORNIA
摘要:The invention herein disclosed provides for methods for the synthesis of polymers from monomers. In particular the method provides for the synthesis of polynucleotides from mononucleotides in the absence of catalytic enzymes. The method comprises providing an aqueous solution having a plurality of phospholipid molecules and monomer molecules; subjecting the aqueous solution to fluctuating temperature conditions; subjecting the aqueous solution to fluctuating cycles of drying and hydrating conditions; subjecting the aqueous solution to fluctuating [H + ] conditions; the fluctuating conditions thereby allowing formation of a chemical bond between at least two monomers to create a polymer. The invention is of particular use in the fields of molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof.
专利号:US-7229797-B1
优先权日:1999-08-20
标 题:Enzymatic synthesis of deoxyribonucleosides
发明人:TISCHER WILHELM; IHLENFELDT HANS-GEORG; BARZU OCTAVIAN; SAKAMOTO HIROSHI; PISTOTNIK ELISABETH; MARLIERE PHILIPPE; POCHET SYLVIE
权利人:PASTEUR INSTITUT
摘要:The present invention relates to a method for the in vitro enzymatic synthesis of deoxyribonucleosides and enzymes suitable for this method.
专利号:US-8486921-B2
优先权日:2006-04-07
标 题:Synthesis of tetracyclines and analogues thereof
发明人:MYERS ANDREW G; BRUBAKER JASON D; SUN CUIXIANG; WANG QIU
权利人:MYERS ANDREW G; BRUBAKER JASON D; SUN CUIXIANG; WANG QIU; HARVARD COLLEGE
摘要:The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The modular synthesis of tetracyclines and tetracycline analogs described provides an efficient and enantioselective route to a variety of tetracycline analogs and polycyclines previously inaccessible via earlier tetra-cycline syntheses and semi-synthetic methods. These analogs may be used as anti-microbial agents or anti-pro liferative agents in the treatment of diseases of humans or other animals.
专利号:US-2007015260-A1
优先权日:2002-03-14
标 题:Synthesis of synthons for the manufacture of bioactive compounds
发明人:WONG CHI-HUEY; LIU JUNJIE; DESANTIS GRACE; BURK MARK
权利人:SCRIPPS RESEARCH INST
摘要:The present invention is based on the discovery that 2-deoxyribose-5-phosphate aldolase (DERA, EC 4.1.2.4) and variants thereof can be used to catalyze sequential asymmetric aldol reactions between a wide variety of donor and acceptor aldehydes. The reaction products typically contain at least two new stereogenic centers and can be produced in enantiomerically pure form. As such, DERA catalyzed asymmetric aldol chemistry can be exploited to produce synthons for the synthesis of a variety of bioactive molecules.