CAS: 2217-41-6; 1-Amino-5,6,7,8-Tetrahydronaphthalene

上下游产品

tetralin 1-Nitronaphthalene 6-nitrotetralin 5-nitro-1,2,3,4-tetrahydronaphthalene N-(5,6,7,8-tetrahydro-[1]naphthyl)-phthalamic acidN-(5,6,7,8-tetrahydro-[1]naphthyl)-phthalamic acid N-phenyl-N'-(5,6,7,8-tetrahydro-[1]naphthyl)-ureaN-phenyl-N'-(5,6,7,8-tetrahydro-[1]naphthyl)-urea N-phenyl-N'-(5,6,7,8-tetrahydro-[1]naphthyl)-thioureaN-phenyl-N'-(5,6,7,8-tetrahydro-[1]naphthyl)-thiourea 1-(Chloroacetamido)-5,6,7,8-tetrahydronaphthalin

1,8-二氨基萘置于氢气体系中,用 甲醇 用作溶剂,150.0 °C,2.2 Mpa 条件下,反应 4.0H,以98.3%的收率获得1-氨基四氢化萘
参考文献:一种以1,8-二氨基萘为原料制备5,6,7,8-四氢-1-萘胺的方法
标题:一种以1,8-二氨基萘为原料制备5,6,7,8-四氢-1-萘胺的方法
摘要:本发明公开了一种以1,8‑二氨基萘为原料制备5,6,7,8‑四氢‑1‑萘胺的方法,所述的方法为:以1,8‑二氨基萘为原料,以雷尼镍为催化剂,以氢气为还原剂,在有机溶剂中,于氢气压力1.5~2.5Mpa,温度120~180oc的条件下反应2‑10小时,反应液过滤浓缩即制得5,6,7,8‑四氢‑1‑萘胺.本发明所述的合成方法操作简便安全,催化加氢是一种绿色合成方法,产品收率高,三废少.

专利信息

专利号:US-2022281888-A1
优先权日:2019-09-25
标题:Bicyclic carboxylates as modulators of transporters and uses thereof
发明人：SANDANAYAKA VINCENT; GORECZNY GREGORY
权利人:NIROGY THERAPEUTICS INC
摘要:The present invention generally relates to the field of transporter modulators, e.g., monocarboxylate transporter inhibitors, and more particularly to new bicyclic enone carboxylate compounds, the synthesis and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with monocarboxylate transporter activity such as in treating cancer and other neoplastic disorders, tissue and organ transplant rejection.

专利号:US-6531470-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-5916899-A
优先权日:1996-10-18
标 题:Isoquinoline derivatives and isoquinoline combinatorial libraries
发明人：KIELY JOHN S; GRIFFITH MICHAEL C
权利人:TREGA BIOSCIENCES INC
摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinolines as well as novel libraries comprised of many such compounds, and methods of synthesizing the libraries.

专利号:US-10458995-B2
优先权日:2016-03-25
标 题 :Combinatorial synthesis and biomarker development
发明人：MOOLA MURALIDHAR REDDY
权利人:MOOLA MURALIDHAR REDDY
摘要:Provided herein are methods, kits, and compositions for use in the diagnosis and treatment of diseases. Peptoids recognized by Alzheimers disease specific antibodies are identified.

专利号:US-2011098483-A1
优先权日:2008-03-27
标题 :Substituted Nitrogen Heterocycles and Synthesis and Uses Thereof
发明人：PETASIS NICOS A; MYSLINSKA MALGORZATA
权利人:UNIV SOUTHERN CALIFORNIA
摘要:The invention relates to a nitrogen heterocycle compound of formula 1: n n n n n n n n n n Also disclosed are a method of synthesizing the compound and use of the compound for treating various diseases and conditions.

专利号:US-6562844-B2
优先权日:1998-01-23
标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.