CAS: 352-34-1; 1-Fluoro-4-Iodobenzene

上下游产品

CAS号1765-93-1 4-氟苯硼酸 | CAS号462-06-6 氟苯 | CAS号630104-26-6 N-ethyl-N-[(4-i... | CAS号460-00-4 对氟溴苯 | CAS号7647-14-5 氯化钠 | CAS号73852-88-7 4-碘苯硼酸频呢醇酯 | CAS号540-37-4 对碘苯胺 | CAS号5122-99-6 4-碘苯硼酸 | CAS号352-13-6 4-氟苯基溴化镁 | CAS号106515-92-8 1-(4-fluorophen... | CAS号10540-41-7 4'-Fluoro-3-bip... | CAS号324-94-7 4-氟-4'-羟基联苯 | CAS号80254-62-2 2-(4-fluorophen... | CAS号10540-33-7 3-(4-fluorophen... | CAS号149500-84-5 6-(4-fluorophen... | CAS号110307-23-8 methyl 2-(4-flu... | CAS号455-15-2 4-氟苯基甲基砜 | CAS号330-84-7 4-氟联苯醚 | CAS号398-21-0 4-溴-4′-氟联苯

4-氟苯硼酸置于copper(II) Nitrate Trihydrate,碘体系中,用 乙腈 用作溶剂,化学反应 6.0H,以68%的收率获得对氟碘苯
参考文献:一种简单有效的铜催化剂,用于在室温下将芳基硼酸转化为芳基碘化物
标题:一种简单有效的铜催化剂,用于在室温下将芳基硼酸转化为芳基碘化物
摘要:简单的cu(no 3)2 .3H 2 O在室温下具有催化芳基硼酸转化为芳基碘的能力.与先前的铜催化方法相比,本方法避免了使用配体,氧化剂以及加热条件.
Doi:10.1016/j.Catcom.2012.11.022

专利信息

专利号:US-7276637-B2
优先权日:2002-08-02
标题:Synthesis of cyclohexanone derivatives
发明人：BRANDS KAREL MARIE JOSEPH; DAVIES ANTONY JOHN; OAKLEY PAUL JOSEPH; SCOTT JEREMY PETER; SHAW DUNCAN EDWARD; TEALL MARTIN RICHARD
权利人:MERCK & CO INC
摘要:A novel process for preparing cyclohexanone derivatives of formula (I) n nis described. The products are useful as gamma secretase inhibitors, or as intermediates in the synthesis of other gamma secretase inhibitors.

专利号:US-10487099-B2
优先权日:2017-06-30
标 题:Synthesis of hypervalent iodine reagents with dioxygen
发明人：POWERS DAVID CHARLES; MAITY ASIM; HYUN SUNG-MIN
权利人:TEXAS A & M UNIV SYS
摘要:Methods of synthesis of hypervalent iodine reagents and methods for oxidation of organic compounds are disclosed.

专利号:US-6600040-B2
优先权日:2000-06-08
标 题:Process for the synthesis of (2R, 2-alpha-R, 3A)-2-[1-(3,5-bis(trifluoromethyl)phenyl)ethoxy]-3-(4-fluorophenyl)-1, 4-oxazine
发明人：BRANDS KAREL M JOS; TSAY FUH-RONG; CONRAD KAREN M; ZHAO MATTHEW M
权利人:MERCK & CO INC
摘要:The present invention is concerned with novel processes for the preparation of (2R, 2-alpha-R, 3a)-2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy-3-(4-fluorophenyl)-1,4-oxazine. This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity.

专利号:EP-1641729-B1
优先权日:2003-07-09
标题:Use of functionalized onium salts as a soluble support for organic synthesis
发明人：VAULTIER MICHEL; GMOUH SAID; HASSINE FATIMA
权利人:CENTRE NAT RECH SCIENT; UNIV RENNES
摘要:The invention relates to the use of a onium salt functionalized by at least one organic function, as a soluble support, in the presence of at least one organic solvent, for organic synthesis of a molecule, in a homogenous phase, by at least one transformation of said organic function. The onium salt enables the synthesized molecule to be released. The onium salt is present in liquid or solid form at room temperature and corresponds to formula A₁⁺, X₁^-, wherein A₁⁺ represents a cation and X₁^- represents an anion.

专利号:US-9573939-B2
优先权日:2011-09-08
标题:Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases
发明人：MCCOMAS CASEY C; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO; PALANI ANANDAN; DAI XING; LIU HONG; HE SHUWEN; DANG QUN
权利人:MCCOMAS CASEY C; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO; PALANI ANANDAN; DAI XING; LIU HONG; HE SHUWEN; DANG QUN; MERCK SHARP & DOHME; MSD ITALIA SRL
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-8242273-B2
优先权日:2005-07-28
标 题:Synthesis of 4/5-pyrimidinylimidazoles via sequential functionalization of 2,4-dichloropyrimidine
发明人：DENG XIAOHU; MANI NEELAKANDHA
权利人:DENG XIAOHU; MANI NEELAKANDHA; JANSSEN PHARMACEUTICA NV
摘要:This invention relates to methods of making pyrimidinyl-substituted imidazole compounds by sequential substitution of the 4- and 2-chloro groups of 2,4-dichloropyrimidine, nucleophilic substitution to form pyrimidinylalkyne derivatives, oxidation to the corresponding 1,2-diketones, and cyclocondensation reactions.