CAS: 606-22-4; 2,6-Dinitroaniline

该化合物是一种有机化合物,其特点是有两种硝基化合物(-NO2)和一个附于苯环的氨基化合物(-NH2),其分子式为C6H5N3O4,其特征为独特的黄色晶体外观,该化合物以其较高的熔点闻名,在有机溶剂中可溶解,但在水中溶解性有限. 2.6-二硝基氮碱主要用于染料,农药和其他化学中间体的合成,它显示出硝基苯的典型特性,包括潜在的毒性和环境关切,需要谨慎地处理和处置.该化合物可发生各种化学反应,例如硝化和减少,使其成为有机合成的多用途建筑块.由于其硝基化合物的硝基混合物,还可能在某些条件下表现出爆炸性,同时强调在与该物质合作时遵守安全议定书的重要性.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号606-21-3 2,6-二硝基氯苯 | CAS号3535-67-9 2-Methoxy-1,3-d... | CAS号88-74-4 2-硝基苯胺 | CAS号55704-91-1 N,o-dinitroaniline | CAS号591-50-4 碘苯 | CAS号609-73-4 邻硝基碘苯 | CAS号606-21-3 2,6-二硝基氯苯 | CAS号45739-20-6 2,6-dichloro-be... | CAS号3970-41-0 2-氯-3-硝基苯胺 | CAS号5388-62-5 4-氯-2,6-二硝基苯胺 | CAS号3694-52-8 3-硝基邻苯二胺 | CAS号16322-19-3 4-硝基-2,1,3-苯噁二唑 | CAS号98-95-3 硝基苯 | CAS号88-75-5 邻硝基苯酚 | CAS号4331-29-7 3H-苯并[D]咪唑-4-胺 | CAS号18771-85-2 5-nitro-9-oxido...

合成工艺路线路线简述

    2,6-二硝基碘苯置于乙醇,氨体系中,化学反应生成 2,6-二硝基苯胺
    参考文献:Koerner,Gazzetta Chimica Italiana,1874,Vol. 4,P. 341
    标题:Koerner,Gazzetta Chimica Italiana,1874,Vol. 4,P. 341

    专利信息


    专利号:US-4204997-A
    优先权日:1979-03-19
    标题 :Asymmetric amination of 1,3-dienes
    发明人:HOBBS CHARLES F; MCMACKINS DUDLEY E
    权利人:MONSANTO CO
    摘要:A process for the asymmetric synthesis of amines which comprises the amination of a conjugated diene having from 4 to about 20 carbon atoms in the presence of a catalyst system comprising a palladium compound and an optically active phosphine ligand containing at least two phosphorus atoms.

    专利号:US-8993762-B2
    优先权日:2013-03-15
    标题 :Total synthesis of thaxtomin A analogues and their intermediates
    发明人:HUANG HUAZHANG; YAN DONG; XUE ZHIJIE; ZHANG HONGBO
    权利人:MARRONE BIO INNOVATIONS INC; MARRONE BIO INNOVATIONS INC
    摘要:Improved synthetic methods for the production of thaxtomin analogs, particularly thaxtomin A, and intermediates therefore such as substituted tryptophans and in particular, 4-nitro-L-tryptophan, and substituted phenyl acrylic acids are disclosed. Bioassays show that the synthetic thaxtomin A is not significantly different from the natural one in herbicidal activity.

    专利号:US-6582952-B1
    优先权日:1997-09-22
    标 题:Method for eliminating a nitrogenated heterocyclic, or aromatic, compound in an effluent
    发明人:LE CAMPION LAURENCE; OUAZZANI JAMAL
    权利人:CENTRE NAT RECH SCIENT; COMMISSARIAT ENERGIE ATOMIQUE
    摘要:This invention relates to a method for the removal of a nitrogen containing heterocyclic or aromatic compound, comprising at least one nitro group, in an effluent by the conversion of said, at least one nitro group into an amine group by means of a reducing agent. The reducing agent can be hydrogen in the presence of Pd/C or a micro-organism. n This invention also relates to a method for the synthesis of 5-amino-1,2,4-triazole-3-one from 5-nitro-1,2,4-triazole-3-one by said method of conversion, that allows one to achieve synthesis yields greater than 80%. n This invention also relates to a colony of the type Bacillus licheniformis capable of converting one or more nitro groups of nitrogen containing heterocyclic compounds into one or more amine groups. This colony has been filed in the CNCM, held by the Pasteur Institute, under the number I-1915.

    专利号:US-10779530-B2
    优先权日:2012-11-07
    标 题:Surfactant composition for use in glyphosate-containing herbicide formulations, glyphosate-containing herbicide formulation, and use of the glyphosate-containing herbicide formulation
    发明人:CASTELANI PRISCILA; CELLA RODRIGO; JORGE ALVIM
    权利人:OXITENO S A IND E COMERCIO
    摘要:A surfactant composition for use in glyphosate-containing herbicide formulations, includes from 5 to 50% by weight of one or more amphoteric surfactants, diluted in solvents derived from the process of synthesis thereof, wherein the surfactants have general formula (I)n nR 1 —(XR 2 ) m —N + (R 3 )(R 4 )—CH 2 —CH(R 5 )—COO −   (I)n nwherein R 1 is hydrogen or C 1-18 hydrocarbyl; each X is independently an ether, thioether, sulfoxide, ester, thioester or amide bond; each R 2 is independently a C 3-6 chain; m is a number from 0 to 8 such that the number of carbon atoms in R 1 —(XR 2 ) m is from 8 to 24; R 3 and R 4 are independently hydrogen or C 1-4 chains; R 5 is hydrogen or methyl. The surfactant composition is used to increase the agronomic efficacy of herbicide formulations containing a high concentration of glyphosate salts. Herbicide formulations including the surfactant composition and uses thereof are also provided.

    专利号:WO-2021074309-A1
    优先权日:2019-10-16
    标 题:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives as fungicides for combating specific phytopathogens
    发明人:WEISS MATTHIAS; QUARANTA LAURA; BOU HAMDAN FARHAN; MAHAJAN ATUL; WILLIAMS SIMON; KILARU JAGADEESH; SEN INDIRA; BIERI STEPHANE; DIGGELMANN MARTIN
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives of formula (I) as well as a method of combating, preventing or controlling the phytopathogens Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale), which comprises applying to the phytopathogen, to the locus of the phytopathogen, or to a plant susceptible to attack by the phytopathogen, or to propagation material thereof, a fungicidally effective amount of a 1-(3-quinolyl)-3,4-dihydroisoquinoline derivative of formula (I). The present description discloses the synthesis of exemplary compounds, formulation examples, relevant biological data (antifungal activity against Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale) when spayed on plants), as well as comparative data against three prior art compounds (e.g. pages 52 to 85; formulation examples; examples A1 to A3; table E; compounds E.01 to E.187; biological examples). Exemplary compounds are e.g.: 5-bromo-1-(8-fluoro-3-quinolyl)spiro[4H-isoquinoline-3,1'- cyclopropane] (example A1) 5-bromo-1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline (example A2) 1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline-5-carbonitrile (example A3)

    专利号:WO-2021074311-A1
    优先权日:2019-10-16
    标题:1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives as fungicides for combating specific phytopathogens
    发明人:WEISS MATTHIAS; QUARANTA LAURA; BOU HAMDAN FARHAN; MAHAJAN ATUL; WILLIAMS SIMON; KILARU JAGADEESH; BIERI STEPHANE; DIGGELMANN MARTIN
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives of formula (I) as well as a method of combating, preventing or controlling the phytopathogens Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale), which comprises applying to the phytopathogen, to the locus of the phytopathogen, or to a plant susceptible to attack by the phytopathogen, or to propagation material thereof, a fungicidally effective amount of a 1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives of formula (I). The present description discloses the synthesis of exemplary compounds, formulation examples, relevant biological data (antifungal activity against Mycosphaerella graminicola, Monographella nivalis, Fusarium culmorum and/or Gibberella zeae when spayed on plants) (e.g. pages 47 to 55; examples A1 and A2; compounds E.01 to E.17; table E). An exemplary compounds is e.g.: 3-(5-bromo-3,3-dimethyl-2,4-dihydro-1 H-isoquinolin-1-yl)-8-fluoro- quinoline (example A1)
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    合成参考文献


    摘要:M.J. Jorgenson and D.R. Hartter. J. Am. Chem. Soc. 85, 878 (1963).
    摘要:P. Tickle, A.G. Briggs and J.M. Wilson. J. Chem. Soc., B 1970, 65.
    摘要:M.I. Vinnik. Uspekhi Khim. 35, 1922 (1966).
    摘要:B.V. Ghidaspov, I.M. Golubkov and I.A. Stepanov. Reakts. Sposobnost Org. Soedin. (Tartu) 7, 931 (1970).
    参考文献:10.1186/1471-2377-8-6
    摘要:Hancock DB, Martin ER, Mayhew GM, Stajich JM, Jewett R, Stacy MA, Scott BL, Vance JM, Scott WK. Pesticide exposure and risk of Parkinson's disease: a family-based case-control study. BMC Neurol. 2008 Mar 28;8():6.
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