CAS: 6372-42-5; Cyclohexyldiphenylphosphine

上下游产品

1-brom°Cyclohexane triphenylphosphine cyclohexyl chloride dicyclohexylzinc(II)Dichlor(cyclohexyl)diphenylphosphoran 1,4-di(cyclohexylphenylphosphino)butane (cyclohexyl)diphenylphosphane oxide cyclohexyl(methyl)phenylphosphine

环己醇置于三(三甲基硅基)硅烷,三乙胺,1,1'-偶氮(氰基环己烷)体系中,用 四氢呋喃,苯 作为反应溶剂,化学反应 90.0H,反应生成 二苯基环己基膦
参考文献:Radical Phosphination Of Organic Halides And Alkyl Imidazole-1-Carbothioates
标题:Radical Phosphination Of Organic Halides And Alkyl Imidazole-1-Carbothioates
摘要:Taking Advantage Of A Radical-Based Methodology,Mild And Chemoselective Phosphination Reactions Of Organic Halide And Alkyl Imidazole-1-Carbothioates Have Been Developed. The Mild Reaction Conditions Allow Labile Functional Groups To Survive During The Reaction.
DOI:10.1021/ja058783H

专利信息

专利号:US-10889599-B2
优先权日:2018-02-27
标 题:1,1-diborylalkyl-1-metal compounds, preparation method thereof, and their applications toward synthesis of 1,1-diboronate ester compounds
发明人：CHO SEUNG HWAN; LEE YEOSAN
权利人:POSTECH ACAD IND FOUND
摘要:The present invention relates to a 1,1-diborylalkyl-1-metal compound including one metal group together with two identical boron groups at the sp3 carbon center, and its use. Specifically, the present invention relates to development of novel organic reactions, synthesis of functional molecules, and synthesis of new drugs by applying the novel 1,1-diboryl-1-metal substituted alkyl compounds to various molecular libraries which could not be synthesized by conventional methodologies.

专利号:US-2023286918-A1
优先权日:2020-07-02
标 题:Manufacturing process for 3,5-dichloropicolinonitrile for synthesis of vadadustat
发明人：JURKAUSKAS VALDAS; JUNG YOUNG CHUN; KWON TAESOO; KANNAN ARUNACHALAM; GONDI VIJAYA BHASKER
权利人:AKEBIA THERAPEUTICS INC
摘要:Disclosed herein are methods and processes of preparing vadadustat or a pharmaceutically acceptable salts thereof, and intermediates (e.g., a compound of Formula (I), (I-F), (II), or (IV), or a pharmaceutically acceptable salts thereof) useful for the synthesis of vadadustat.

专利号:WO-2021033165-A1
优先权日:2019-08-21
标 题:Process for synthesis of pyrazolidinone compounds
发明人：MATHUR SUCHET SARAN; MHATRE HRIDAYNATH VISHWANATH; PEDHAVI VISHAL PARSHURAM
权利人:GHARDA CHEMICALS LTD
摘要:The present disclosure relates to a process for the synthesis of pyrazolidinone, particularly alkyl 2-(3-chloropyridin-2-yl)-5-oxo-pyrazolidine-3-carboxylate (pyrazolidinone) compound. The process of the present disclosure is simple, economical, and produces alkyl 2-(3-5 chloropyridin-2-yl)-5-oxo-pyrazolidine-3-carboxylate with a comparatively high yields.

专利号:US-12049470-B2
优先权日:2021-02-01
标 题 :MK2 inhibitors, the synthesis thereof, and intermediates thereto
发明人：RUCHELMAN ALEXANDER L; COOMBS JOHN R; ZHU KEMING; LIM DANIEL; JOE CANDICE LEE; GEORGE DAVID T; ZHENG BIN; LIN DONG
权利人:CELGENE CORP
摘要:The present disclosure provides novel synthetic intermediates useful in the synthesis of MK2 kinase inhibitors.

专利号:WO-2025024449-A1
优先权日:2023-07-24
标 题:Processes and intermediates for synthesis of mrtx1133
发明人：GHARBAOUI TAWFIK; SCATTOLIN THOMAS; CHEN CHENG
权利人:MIRATI THERAPEUTICS INC
摘要:The present invention relates to new synthetic routes of synthesizing MRTX1133. The invention also provides intermediates used in the provided synthetic routes.

专利号:US-2022056025-A1
优先权日:2018-09-25
标 题:Synthesis of pyrido[2,3-d]pyrimidin-7(8h)-ones
发明人：BROWN ADAM ROSS; DESROSIERS JEAN-NICOLAS; DUAN SHENGQUAN; HAWKINS JOEL MICHAEL; HAYWARD CHERYL MYERS; MALONEY MARK THOMAS; MONFETTE SEBASTIEN; PERFECT HAHDI HAKIMIOUN; WIDLICKA DANIEL WILLIAM
权利人:PFIZER
摘要:This invention relates to novel methods to prepare substituted pyrido[2,3-d]pyrimidin-7(8H)-ones, and salts and stereoisomers thereof, as well as intermediates useful for the preparation of such compounds.