CAS: 89284-52-6; 1,4-Dibromo-2-Iodobenzene

• 英文名称1,4-Dibromo-2-Iodobenzene
• 中文名称2,5-二溴碘苯
• IUPAC名称1,4-dibromo-2-iodobenzene
• 其它别名1,4-二溴-2-碘苯
• CAS编号89284-52-6
• MFCD编号:MFCD07778993
• EINECS号:810-344-0
• 分子式:C6H3Br2I
• 分子量:361.8
• 产品CID: 1914166
• 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

• 相似结构搜索
• 产品信息参考
• InChIKey: VLRYPRKTXDPVNN-UHFFFAOYSA-N
• InChI=1S/C6H3Br2I/c7-4-1-2-5(8)6(9)3-4/h1-3H…
• 计算化学: 氢键受体数0.0氢键供体数0.0可旋转键数0.0

物理性质

• 熔点41 °C
• 沸点303.6°C at 760 mmHg
• 闪点137.4 °C
• 密度2.514g/cm3
• PSA:0.0
• LogP:3.8162
• 折射率1.682
• 溶解性Soluble In Toluene
• 外观形态白色至淡黄色至深绿色粉末至晶体
• 储存条件置于阴暗处,密封, 常温干燥保存
• 产品应用该化合物用作合成药品,农用化学品,染料,塑料和功能聚合材料.

MSDS等安全信息

• GHS象形图
• GHS符号GHS07;
  注释: Exclamation mark
• 危险类别急性毒性 类别4(经口)
  特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2
• 警示词Warning(警告)
• 危险描述H302 |吞咽有害.
  H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
  H319 |造成严重眼刺激.
• 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
• 危险品标志Xi

欧盟法规

上下游产品

合成工艺路线路线简述

• 106-37-6 = 89284-52-6
  反应条件:1.1 Reagents: Butyllithium,2,2,6,6-Tetramethylpiperidine Solvents: Tetrahydrofuran,Hexane; 10 Min,0 °C1.2 Reagents: 2-Propanol,2-Methyl-,Zinc Salt Solvents: Pentane,Tetrahydrofuran; -78 °C; 30 Min,0 °C1.3 Solvents: Tetrahydrofuran; -78 °C; 24 H,-30 °C1.4 Reagents: Iodine Solvents: Tetrahydrofuran; 1 H,Rt1.5 Reagents: Sodium Thiosulfate,Ammonium Chloride Solvents: Water
  标题:Generation And Suppression Of 3-/4-Functionalized Benzynes Using Zinc Ate Base (Tmp-Zn-Ate): New Approaches To Multisubstituted Benzenes
  作者:Uchiyama,Masanobu; Kobayashi,Yuri; Furuyama,Taniyuki; Nakamura,Shinji; Kajihara,Yumiko; Et Al
  参考文献:Journal Of The American Chemical Society 日期:2008 卷标:130(2) 页码:472-480]
  
  = 89284-52-6
  反应条件:1.1 Reagents: Hydrochloric Acid Solvents: Water; 30 Min,80 °C; 80 °C -> Rt; Rt -> 0 °C1.2 Reagents: Sodium Nitrite; 0 °C; 30 Min,0 °C1.3 Reagents: Potassium Iodide Solvents: Water; 0 °C; 0 °C -> Rt; 12 H,Rt
  标题:Synthesis,Characterization,And Structure-Property Investigation Of Conformationally Rigid Regioisomers Of Poly(P-Phenylene Ethynylene)S
  作者:Sen,Choong Ping; Valiyaveettil,Suresh
  参考文献:Journal Of Polymer Science 日期:2016 卷标:54(22) 页码:3652-3662]
  
  = 89284-52-6
  反应条件:1.1 Reagents: Sodium Nitrite,Hydrochloric Acid Solvents: Acetonitrile,Water; 50 °C; 0 °C; 45 Min,0 °C1.2 Reagents: Potassium Iodide Solvents: Water; Cooled; 20 Min,Cooled
  标题:Controlling The Complexity And Interconversion Mechanisms In Self-Assembled [fe2L3]4+ Helicates And [fe4L6]8+ Cages
  作者:Siddique,Rashid G.; Arachchige,Kasun S. A.; Al-Fayaad,Hydar A.; Thoburn,John D.; Mcmurtrie,John C.; Et Al
  参考文献:Angewandte Chemie 日期:2022 卷标:61(7)]
  
  = 89284-52-6
  反应条件:1.1 Reagents: Sodium Nitrite,Hydrochloric Acid Solvents: Water1.2 Reagents: Potassium Iodide Solvents: Water
  标题:A Porphyrin Tetramer For A Positive Homotropic Allosteric Recognition System: Efficient Binding Information Transduction Through Butadiynyl Axis Rotation
  作者:Kubo,Y.; Ikeda,M.; Sugasaki,A.; Takeuchi,M.; Shinkai,S.
  参考文献:Tetrahedron Letters 日期:2001 卷标:42(42) 页码:7435-7438]
  
  = 89284-52-6
  反应条件:1.1 Reagents: Sodium Nitrite,Hydrochloric Acid Solvents: Acetonitrile,Water; Cooled; 40 Min,Cooled1.2 Reagents: Potassium Iodide Solvents: Water; 20 Min,Cooled; Rt; 3 H,Rt1.3 Reagents: Sodium Sulfite; Rt
  标题:Synthesis And Characterization Of D-A Structure Mesogen Jacketed Polymers Containing Benzodithiophene In Main Chains
  作者:Wan,Liying; Li,Peijie; Yi,Fan
  参考文献:Gaofenzi Cailiao Kexue Yu Gongcheng 日期:2021 卷标:37(7) 页码:27-34]
  
  106-37-6 = 89284-52-6
  反应条件:1.1 Reagents: Dichloro(N,N,N′,N′-Tetramethylethylenediamine)Zinc Solvents: Tetrahydrofuran; Rt -> -40 °C1.2 Reagents: Piperidine,2,2,6,6-Tetramethyl-,Lithium Salt (1:1); 1 H,-40 °C1.3 Reagents: Iodine; 1 H,-40 °C
  标题:Deprotonative Generation And Trapping Of Haloaryllithium In A Batch Reactor
  作者:Feng,Yuxuan; Yukioka,Taro; Matsuyama,Mei; Mori,Atsunori; Okano,Kentaro
  参考文献:Organic Letters 日期:2023 卷标:25(17) 页码:3013-3017]
  
  = 89284-52-6
  反应条件:1.1 Reagents: P-Toluenesulfonic Acid,Sodium Nitrite,Potassium Iodide Solvents: Acetonitrile,Water; 15 Min,10 °C; 10 Min,10 °C; 1 H,10 °C -> Rt
  标题:Bicyclic Phenyl-Ethynyl Architectures: Synthesis Of A 1,4-Bis(Phenylbuta-1,3-Diyn-1-Yl) Benzene Banister
  作者:Bannwart,Linda Maria; Muentener,Thomas; Rickhaus,Michel; Jundt,Lukas; Haeussinger,Daniel; Et Al
  参考文献:Chemistry - A European Journal 日期:2021 卷标:27(20) 页码:6295-6307]
  
  = 89284-52-6
  反应条件:1.1 Reagents: Sodium Nitrite,Hydrochloric Acid Solvents: Acetonitrile,Water; Rt -> 10 °C; 5 - 10 °C; 20 Min,5 - 10 °C1.2 Reagents: Potassium Iodide Solvents: Water; 20 Min,5 - 10 °C
  标题:Synthesis And Optical Properties Of Conjugated Polymers Containing Polyoxometalate Clusters As Side-Chain Pendants
  作者:Xu,Bubin; Lu,Meng; Kang,Jeonghee; Wang,Degang; Brown,John; Et Al
  参考文献:Chemistry Of Materials 日期:2005 卷标:17(11) 页码:2841-2851]
  
  106-37-6 = 89284-52-6
  反应条件:1.1 Reagents: Piperidine,2,2,6,6-Tetramethyl-,Lithium Salt (1:1) Solvents: Tetrahydrofuran; 40 Min,-80 °C; -80 °C -> -90 °C1.2 Reagents: Iodine; -90 °C; 30 Min,-80 °C; -80 °C -> -20 °C1.3 Reagents: Sulfuric Acid Solvents: Water; -20 °C
  标题:Regioselective Generation Of Aryllithiums From Substituted Bromobenzenes Xc6H4Br (X = 4-Br,4-I,4-Cn,2-Cn)
  作者:Lulinski,Sergiusz; Serwatowski,Janusz; Szczerbinska,Magdalena
  参考文献:European Journal Of Organic Chemistry 日期:2008 卷标:(10) 页码:1797-1801]
  
  = 89284-52-6
  反应条件:1.1 Reagents: Sodium Nitrite,Sulfuric Acid Solvents: Acetic Acid,Water; 0 °C; 1 H,0 °C1.2 Reagents: Urea Solvents: Water; 0 °C1.3 Reagents: Potassium Iodide Solvents: Water; Rt; 1 H,Rt
  标题:Synthesis,Photophysics,And Electroluminescence Of New Quinoxaline-Containing Poly(P-Phenylenevinylene)S
  作者:Karastatiris,Panayiotis; Mikroyannidis,John A.; Spiliopoulos,Ioakim K.; Kulkarni,Abhishek P.; Jenekhe,Samson A.
  参考文献:Macromolecules 日期:2004 卷标:37(21) 页码:867-7878]
  
  = 89284-52-6
  反应条件:1.1 Reagents: Hydrochloric Acid Solvents: Water; 30 Min,80 °C1.2 Reagents: Sodium Nitrite Solvents: Water; 0 °C; 30 Min,0 °C1.3 Reagents: Potassium Iodide Solvents: Water; 0 °C; 6 H,0 °C -> Rt
  标题:Acetophenone And Thiophene Side-Arm Polyaryleneethynylene Conjugated Polymers For Enrichment Of Electronic Applications
  作者:Arun Kumar,Gunasekaran; Chandramohan,Ayyavu; Gomathi Priya,Ponnaiah; Alagar,Muthukaruppan
  参考文献:Polymer International 日期:2020 卷标:69(4) 页码:429-438]
  
  = 89284-52-6
  反应条件:1.1 Reagents: Hydrochloric Acid Solvents: Water; 30 H,80 °C; 80 °C -> Rt1.2 Reagents: Sodium Nitrite Solvents: Water; 0 °C; 30 Min,0 °C1.3 Reagents: Potassium Iodide Solvents: Water; 6 H,0 °C -> Rt
  标题:Functional Phenylethynylene Side Arm Poly(Arylene Ethynylene) Conjugated Polymers: Optical And Electrochemical Behavior For Enrichment Of Electronic Applications
  作者:Arun Kumar,G.; Gomathi Priya,P.; Alagar,M.
  参考文献:New Journal Of Chemistry 日期:2018 卷标:42(8) 页码:5767-5773]
  
  = 89284-52-6
  反应条件:1.1 Reagents: Hydrochloric Acid Solvents: Water; Rt -> 80 °C; 30 Min,80 °C; 80 °C -> 0 °C1.2 Reagents: Sodium Nitrite; < 10 °C; 30 Min,0 °C1.3 Reagents: Potassium Iodide Solvents: Water; < 10 °C; 0 °C -> Rt; 12 H,Rt
  标题:Palladium-Catalyzed Aryl Amination- Heck Cyclization Cascade: A One-Flask Approach To 3-Substituted Indoles
  作者:Jensen,Thomas; Pedersen,Henrik; Bang-Andersen,Benny; Madsen,Robert; Joergensen,Morten
  参考文献:Angewandte Chemie 日期:2008 卷标:47(5) 页码:888-890

专利信息

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• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管