CAS: 23283-97-8; (+)-Isomenthol
该化合物是源自月球的循环单体酒精,其特征是其性能,作为异族新醇的对应体之一,特别是(+)形式,具有薄膜芳香.该化合物在室内温度下一般是无色的,可粉黄黄色液体,在酒精和醚中溶解,但在水中则因其疏水特性而较少溶解.其分子结构具有环形特征,具有氢氧化物组,有助于其功能性.(+)-Isomenthol在香味和调味行业以及个人护理产品的配制中普遍使用,因为其香味和冷却感.此外,该化合物在制药和有机合成中作为土气建筑块具有潜在用途.其安全特征表明毒性低,适合各种消费品.
相似化合物
89-78-1 2216-52-6 2623-23-6物理性质
- 熔点77-83 °C
- 沸点218-219 °C at 760 mmHg
- 闪点93.3 °C
- 密度0.89g/cm3
- pKa:15.30±0.60(预测)
- PSA:20.23
- LogP:2.4395
- 折射率1.457
- 蒸汽压0.0323mmHg at 25°C
- 溶解性Chloroform (Sparingly), Ethanol (Sparingly), Methanol (Slightly)
- 敏感性D,L-MENTHOL is incompatible with butyl chloral hydrate, camphor, phenol, chloral hydrate, Exalgine, betanaphthol, resorcinol or thymol in triturations; potassium permanganate, chromium trioxide and pyrogallol. It is also incompatible with strong oxidizers. (NTP, 1992)
- 外观形态白色至类白色晶体
- 储存条件2-8°C
- 产品应用该化合物用于准备磷活性剂的试剂.
MSDS等安全信息
- GHS象形图
- GHS符号GHS07;
注释: Exclamation mark - 危险类别皮肤腐蚀/刺激 类别2
严重眼刺激 类别2
特定目标器官毒性 - 单次接触 类别3
严重眼刺激 类别2A - 警示词Warning(警告)
- 危险描述H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
H335 |可能引起呼吸道刺激. - 防范说明P264-P280-P302+P352-P362+P364
- UN编号NONH for all modes of transport
- 安全声明22-24/25
- 危险类别码A mucous membrane irritant; [Hawley] Emergency treatment: Peppermint oil; [HSDB] A skin, eye, mucous membrane, and upper respiratory tract irritant; [CAMEO] A mild to moderate skin and eye irritant; [eChemPortal: SIDSUNEP] Peppermint oil causes CNS depression and hypothermia in rat feeding studies; Menthol causes ataxia, seizures, and respiratory depression in lethal dose studies of rats; It causes kidney damage and cystic lesions of the cerebellum in chronic studies; [Haddad, p. 1439] Included in list of established contact allergens in humans; [EC: Scientific Committee on Consumer Safety: Fragrance allergens in cosmetic products (2011)] An irritant; May cause serious eye injury; [MSDSonline] See l-Menthol and d-Menthol.
- WGK Germany3
欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
CAS号89-83-8 麝香草酚 | CAS号2216-51-5 (-)-薄荷醇 | CAS号2216-52-6 (+)-新薄荷醇 | CAS号1044169-05-2 (1R,2R,4R)-2-溴-... | CAS号1196-31-2 (+)-异薄荷酮 | CAS号500-00-5 para-3-menthene合成工艺路线路线简述
百里酚置于氢气,镍体系中,化学反应生成(+)-异薄荷醇
参考文献:Brunel,Bulletin De La Societe Chimique De France,1905,Vol. <3> 33,P. 269,500
标题:Brunel,Bulletin De La Societe Chimique De France,1905,Vol. <3> 33,P. 269,500
海关参考信息
- 2905122000-异丙醇
2905141000-异丁醇
2905142000-仲丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.
专利号:US-6225341-B1
优先权日:1995-02-27
标 题:Compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
权利人:GILEAD SCIENCES INC
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.
专利号:US-2003236435-A1
优先权日:2002-05-15
标题 :Synthesis of 2-alkylcysteine via substituted thiazoline ester
专利号:EP-1529037-B1
优先权日:2002-05-15
标题 :Synthesis of 2-alkylcysteines, 2-(hydroxylated phenyl)-4-alkylthiazoline-4-carboxylic acids and derivatives thereof
专利号:JP-2005538950-A
优先权日:2002-05-15
标题:Synthesis of 2-alkylcysteine, 2- (hydroxylated phenyl) -4-alkylthiazoline-4-carboxylic acids and their derivatives
专利号:JP-2007001986-A
优先权日:2002-05-15
标 题 :Synthesis of 2-alkylcysteine, 2- (hydroxylated phenyl) -4-alkylthiazoline-4-carboxylic acids and their derivatives
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销售经理: 王志成经理
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📌 第三方产品分析报告
主要参考文献
参考标题:Oxidation Of Azides By The Hof.Ch3Cn: A Novel Synthesis Of Nitro Compounds作者:Mira Carmeli,Shlomo Rozen |发布日期:2006.6.1
摘要:Aromatic Rings, Ketones, Nitriles, Halides, Alcohols, And Esters Are Tolerated. Sulfides React With Hof.Ch3Cn Usually At The Same Rate As Azides. Amines And Olefins, However, React Faster, So They Have To Be Protected First. Nitro Derivatives With Various Oxygen Isotopes Can Be Made Using The Labeled H18Of.Ch3Cn. In The Case Of Chiral Azides The Stereochemistry Around The Nitrogen-Bonded Carbons Is Retained
合成参考文献
摘要:Joosten, A.; Brioche, J., Science of Synthesis: Modern Strategies in Organofluorine Chemistry , (2024) 1, 24.
参考文献:10.1186/1752-153x-5-26
摘要:Esmaeili A, Hashemi E. Biotransformation of myrcene by Pseudomonas aeruginosa. Chemistry Central Journal. 2011 May 24;5(1). doi: 10.1186/1752-153x-5-26.
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