CAS: 59004-18-1; 3-(Trimethoxysilyl)Propyl Acetate

相似化合物

4369-14-6 33580-59-5 2530-85-0

Sodium Acetate,3-氯丙基三甲氧基硅烷置于hexaethylguanidinium Chloride体系中,化学反应 7.0H,以96%的收率获得产物乙酰氧基丙基三甲氧基硅烷
参考文献:Process For Producing Organoalkoxysilanes From Organic Acids Or Cyanates And Haloalkylalkoxysilanes
标题:Process For Producing Organoalkoxysilanes From Organic Acids Or Cyanates And Haloalkylalkoxysilanes
摘要:一种制备含有来自有机酸或氰酸氢的一个或多个有机功能基团的有机烷氧基硅烷的方法,通过使用固体胍盐作为相转移催化剂的连续或批处理过程,使液相卤代烷基烷氧基硅烷和固相有机酸或金属氰酸盐的碱金属或碱土金属盐或铵盐之间的反应.

专利信息

专利号:US-9981239-B2
优先权日:2015-04-21
标题:Devices and methods for oligonucleic acid library synthesis
发明人：BANYAI WILLIAM; PECK BILL JAMES; FERNANDEZ ANDRES; CHEN SIYUAN; INDERMUHLE PIERRE; MARSH EUGENE P
权利人:TWIST BIOSCIENCE CORP
摘要:Devices and methods for de novo synthesis of large and highly accurate libraries of oligonucleic acids are provided herein. Devices include structures having a main channel and microchannels, where the microchannels have a high surface area to volume ratio. Devices disclosed herein provide for de novo synthesis of oligonucleic acids having a low error rate.

专利号:US-8859196-B2
优先权日:2002-06-20
标 题:Antireflective coatings for high-resolution photolithographic synthesis of DNA arrays
发明人：TRULSON MARK O; MCGALL GLENN H; SYWE BEI-SHEN; KAJISA LISA T; TRUONG DANA; RAVA RICHARD P; GOLDBERG MARTIN J
权利人:TRULSON MARK O; MCGALL GLENN H; SYWE BEI-SHEN; KAJISA LISA T; TRUONG DANA; RAVA RICHARD P; GOLDBERG MARTIN J; AFFYMETRIX INC
摘要:The present invention provides an array of polymers and methods of forming arrays of polymers by providing a substrate having a first layer including one or more dielectric coatings on a solid support and a second layer including a plurality of polymers disposed on the first layer. The invention also provides methods for forming an array of polymers on a substrate using light-directed synthesis by providing a substrate having a first layer including one or more dielectric coatings on a solid support, derivatizing the first layer by contacting the first layer with a silanation reagent, and a second layer disposed on said first layer wherein the second layer includes functional groups protected with a photolabile protecting group.

专利号:US-8637434-B2
优先权日:1996-04-17
标题 :System for photolithographic synthesis of polymer arrays
发明人：GOLDBERG MARTIN J; DIGGELMAN MARTIN; HUBBELL EARL A; MCGALL GLENN H; NAM NGO; MORRIS MACDONALD S; YAMAMOTO MELVIN; TAN JENNIFER; RAVA RICHARD
权利人:AFFYMETRIX INC
摘要:The present invention provides novel processes for the large scale preparation of arrays of polymer sequences wherein each array includes a plurality of different, positionally distinct polymer sequences having known monomer sequences. The methods of the invention combine high throughput process steps with high resolution photolithographic techniques in the manufacture of polymer arrays.

专利号:US-6508988-B1
优先权日:2000-10-03
标 题 :Combinatorial synthesis system
发明人：VAN DAM R MICHAEL; UNGER MARC A; QUAKE STEPHEN R
权利人:CALIFORNIA INST OF TECHN
摘要:The present invention provides a chemical reaction apparatus for synthesizing an array of compounds and methods for using the same. In particular, the chemical reaction apparatus of the present invention comprises a solid support base, a first elastic member attached to the solid support base, and a first plurality of flow channels between the solid support base and the first elastic member. In addition, the solid support base comprises a functional group within at least a portion of the first plurality of flow channels for attaching compounds thereto. Optionally, the chemical reaction apparatus may further comprise a second plurality of flow channels which are in a different direction than the first plurality of flow channels. Moreover, the chemical reaction apparatus of the present invention can also include a second elastic member attached to the first elastic member. A plurality of pressure channels present in between the first and the second elastic members allows control of fluid flow within the first plurality of flow channels and/or the second plurality of flow channels.

专利号:US-7097809-B2
优先权日:2000-10-03
标 题:Combinatorial synthesis system
发明人：VAN DAM MICHAEL; UNGER MARC A; QUAKE STEPHEN R
权利人:CALIFORNIA INST OF TECHN
摘要:The present invention provides a microfluidic device for synthesizing an array of compounds and methods for using the same. In particular, the microfluidic device of the present invention comprises a solid support base, an elastomeric layer attached to the solid support, and a plurality of flow channels located within the interface between the solid support and the elastomeric layer. In addition, the solid support comprises a functional group for forming a bond with a reactive reagent. In some embodiments, the microfluidic device further comprises a second plurality of flow channels that intersect the first plurality of flow channels. A plurality of control channels are also present in the microfluidic devices of the present invention. The control channels can be actuated to regulate flow of fluids within the flow channel(s).

专利号:WO-2023196499-A1
优先权日:2022-04-07
标 题:Substrate cleavage for nucleic acid synthesis
发明人：LACKEY JEREMY; DODD DAVID; LANGNER HEERA
权利人:TWIST BIOSCIENCE CORP
摘要:Disclosed herein are methods and compositions for cleavage of nucleic acids from a surface of a solid support. Further described herein are cleavage methods compatible with enzymatic and chemical nucleic acid synthesis methods.