CAS: 6271-78-9; 6-Chloropyridine-3-Carboxamide

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33252-28-7 97004-04-1 54189-82-1

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6-溴烟酸置于草酰氯,苯体系中,化学反应生成 6-氯烟酰胺
参考文献:Studies On The Acid Hydrolysis Of α-Halogenated Pyridine Compounds1
标题:Studies On The Acid Hydrolysis Of α-Halogenated Pyridine Compounds1
摘要:
DOI:10.1021/jo01156A002

专利信息

专利号:US-2007275968-A1
优先权日:2004-09-07
标 题 :Substituted Biphenyl Derivative
发明人：KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
权利人:KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
摘要:The present invention relates to a biaryl derivative or a pharmacologically acceptable salt thereof having an excellent collagen-synthesis inhibition activity. A biaryl derivative having a structure represented by the following General Formula (I) or a pharmacologically acceptable salt thereof: n nwherein n R 1 represents a C 6 -C 10 aryl group which is substituted with one to three group(s) each independently selected from the group consisting of a group defined by formula R-L-, a di-(C 1 -C 6 alkyl)amino group, a di-(C 1 -C 6 alkyl)aminosulfonyl group, a hydroxyaminocarbonyl group, and a halogen atom, and so on; R represents a C 1 -C 6 alkyl group, and so on; L represents a sulfonyl group, an aminosulfonyl group, or a sulfonylamino group, and so on; R 2 represents a hydrogen atom, and so on; A represents a group defined by formula (II), (III), or (IV); R 3 represents a C 1 -C 6 alkyl group, and so on; and R 4 represents a C 1 -C 6 alkyl group, and so on.

专利号:US-RE47415-E
优先权日:2009-02-17
标题:Pyrimidinecarboxamides as CXCR2 modulators
发明人：MAEDA DEAN Y; ZEBALA JOHN A
权利人:SYNTRIX BIOSYSTEMS INC
摘要:There is disclosed pyridine- and pyrimidinecarboxamide compounds useful as pharmaceutical agents, synthesis processes, and pharmaceutical compositions which include pyridine- and pyrimidinecarboxamides compounds. More specifically, there is disclosed a genus of CXCR2 inhibitor compounds that are useful for treating a variety of inflammatory and neoplastic disorders.

专利号:US-6649627-B1
优先权日:1998-06-18
标 题 :Phenoxylpropanolamines, method for the production thereof and pharmaceutical compositions containing the same
发明人：CECCHI ROBERTO; CROCI TIZIANO; GUZZI UMBERTO; MARSAULT ERIC
权利人:SANOFI SYNTHELABO
摘要:The invention concerns compounds of formula (Ia)whereinR1a represents hydrogen, an -S(O)z -(C1-C4)Alk group, a -CO(C1-C4)Alk group, an -NHSO2-(C1-C4)Alk group, an NCHl (C1-C4) Alk group, a 2-furyl group or a halogen;R2 represents hydrogen or a (C1-C4)Alk group, a (C1-C4) alkoxyl group, a halogen, -COOH, -COO(C1-C4)Alk, -CN, -CONR3R4, -NO2, -SO2NH2, -NHSO2(C1-C4)Alk;m and n are independently 0, 1 or 2;R3 and R4 independently represent hydrogen or a (C1-C4)Alk group;Z is 1 or 2and their salts or solvates, the pharmaceutical compositions that contain them, the process for their preparation, and intermediate synthesis products.