CAS: 6315-89-5; 3,4-Dimethoxyaniline

上下游产品

CAS号709-09-1 3,4-二甲氧基硝基苯 | CAS号87587-62-0 4-azido-1,2-dim... | CAS号2859-78-1 3,4-二甲氧基溴苯 | CAS号109682-63-5 1,1,1-trichloro... | CAS号91-16-7 1,2-二甲氧基苯 | CAS号13546-91-3 N-hydroxy-3,4-d... | CAS号1521-41-1 3,4-二甲氧基苯甲酰胺 | CAS号2169-98-4 3,4-二甲氧基苯甲醛肟 | CAS号4998-07-6 4,5-二甲氧基-2-硝基苯甲酸 | CAS号106107-48-6 6-(叔丁氧基羰基氨基)-2,... | CAS号107572-53-2 (6,7-dimethoxyq... | CAS号35654-56-9 4-氯-6,7-二甲氧基喹啉 | CAS号490-64-2 2,4,5-三甲氧基苯甲酸 | CAS号37527-66-5 异氰酸3,4-二甲氧基本酯 | CAS号37519-14-5 3-羟基对乙酰氨基酚 | CAS号14382-91-3 2-羟基-4,5-二甲氧基苯甲醛 | CAS号398-62-9 4-氟-1,2-二甲氧基苯 | CAS号4460-86-0 2,4,5-三甲氧基苯甲醛 | CAS号436088-80-1 (3,4-二甲氧基苯基)-呋喃-2-甲胺

邻苯二甲醚置于o-(4-Nitrobenzoyl)Hydroxylammonium Trifluoromethanesulfonate,Iron(II) Bromide,双三氟甲烷磺酰亚胺银盐体系中,用 2,2,2-三氟乙醇,水 作为反应溶剂,化学反应 2.0H,以84%的收率获得产物3,4-二甲氧基苯胺
参考文献:在温和条件下用氧化还原活性胺化试剂对(杂)戊烯进行fe催化胺化
标题:在温和条件下用氧化还原活性胺化试剂对(杂)戊烯进行fe催化胺化
摘要:据报道,使用新型的氧化还原活性胺化试剂,新型有效的铁催化的芳烃直接ch-H胺化(nh 2).该反应很简单,可以在空气,温和和氧化还原中性条件下进行.该方案具有广泛的底物范围,可用于生物活性化合物的后期修饰.机理研究表明,自由基途径可能参与了这种转化.
DOI:10.1002/chem.201605476

专利信息

专利号:US-7109377-B2
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
发明人：SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
权利人:HARVARD COLLEGE
摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

专利号:US-6080860-A
优先权日:1992-08-31
标 题:Methods of making ureas and guanidines including, terazosin, prazosin, doxazosin, tiodazosin, trimazosin, quinazosin and bunazosin (exemplary of 2-substituted quinazoline compounds), and meobentine, and bethanidine and intermediates therefor
发明人：KARIMIAN KHASHAYAR; MURTHY KESHAVA; HALL DARREN
权利人:BRANTFORD CHEMICALSS INC
摘要:Novel methods for the synthesis of substituted ureas and guanidines including Terazosin, Prazosin, Doxazosin, Tiodazosin, Trimazosin, Quinasin and Bunazosin (exemplary of 2-amino substituted Quinazolines), Meobentine and Bethanidine and novel intermediates suitable for use in such methods of synthesis are taught.

专利号:US-9884067-B2
优先权日:2013-03-14
标 题:Androgen receptor down-regulating agents and uses thereof
发明人：NJAR VINCENT C O; GEDIYA LALJI K; PURUSHOTTAMACHAR PURANIK; GODBOLE ABHIJIT; KWEGYIR AFFUL ANDREW; VASAITIS TADAS
权利人:UNIV OF MARYLAND EASTERN SHORE; UNIV JEFFERSON; UNIV MARYLAND
摘要:The present disclosure provides the design and synthesis of novel steroidal compounds that cause down-regulation of the androgen receptor (AR), both full length and splice variant. The compounds are potential agents for the treatment of all forms of prostate cancer and other diseases that depend on functional AR.

专利号:US-4469701-A
优先权日:1983-06-23
标题 :Pyrrolid-3-en-2-ones and pharmaceutical methods of use thereof
发明人：DEBAUN JACK R; PALLOS FERENC M; MATSUMOTO KENT E; ROSS JOHN H
权利人:STAUFFER CHEMICAL CO
摘要:Novel compounds having the structural formula ##STR1## wherein R 1 and R 2 are independently selected from the group consisting of hydrogen, halo, alkyl, haloalkyl, thioalkyl, thiohaloalkyl, alkoxy, cyano and nitro are provided. The compounds have various pharmacological effects, including cardiotropic, hypoglycemic, hypocholesterolemic and/or antiulcerative effects in mammals. Methods of achieving these various pharmacological effects in mammals by administering the compounds thereto are provided. Pharmaceutical compositions and formulations including the compounds are provided along with methods of synthesis of the novel compounds.

专利号:WO-9931506-A9
优先权日:1997-12-18
标题:Parallel solution phase synthesis of lactams
发明人：CWI CYNTHIA LYNN; SCOTT WILLIAM LEONARD
权利人:LILLY CO ELI; CWI CYNTHIA LYNN; SCOTT WILLIAM LEONARD
摘要:The present invention provides a parallel solution phase process for making combinatorial arrays of lactam derivatives which are useful for screening for therapeutically useful compounds.

专利号:US-4536334-A
优先权日:1979-06-28
标题 :Preparation of β-lactam derivatives
发明人：SUNAGAWA MAKOTO; MATSUMURA HARUKI; INOUE TAKAAKI; HIROHASHI TOSHIYUKI
权利人:SUMITOMO CHEMICAL CO
摘要:A process for preparing a β-lactam derivative having a hydrogen atom on the nitrogen atom of the β-lactam ring, which comprises reacting a β-lactam derivative having a mono- or diarylmethyl group on the nitrogen atom of the β-lactam ring with an acid or ceric ammonium nitrate to cleave the bond between the nitrogen atom and the mono- or diarylmethyl group; and novel β-lactam derivatives useful as intermediates for the synthesis of pharmaceutical agents.