CAS: 16355-00-3; (R)-1-Phenylethane-1,2-Diol

相似化合物

25779-13-9 93-56-1 2979-22-8

上下游产品

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D-扁桃酸置于lithium Aluminium Tetrahydride体系中,用 四氢呋喃 用作溶剂,化学反应 2.5H,以71%的收率获得(R)-1-苯基-1,2-乙二醇
参考文献:Snbr4催化二芳基甲醇与2-萘酚衍生物的非对映混合物的手性诱导非对映聚合friedel-Crafts烷基化反应
标题:Snbr4催化二芳基甲醇与2-萘酚衍生物的非对映混合物的手性诱导非对映聚合friedel-Crafts烷基化反应
摘要:非对映收敛方式:溴化锡(iv)催化的二芳基甲醇的非对映混合物的friedel-Crafts烷基化反应,每个都带有手性助剂,与2-萘酚衍生物的收率高,选择性高.
Doi:10.1002/ejoc.201701280

专利信息

专利号:US-6838581-B2
优先权日:2002-12-04
标题:Process for the preparation of enantiomerically pure 3-phenyl-3-hydroxypropylamine
发明人：KUMAR PRADEEP; PANDEY RAJESH KUMAR
权利人:COUNCIL SCIENT IND RES
摘要:The present invention relates to an improved process for the synthesis of enantiomerically pure 3-phenyl-3-hydroxypropylamine of formula I; more particularly the present invention relates to the said process using styrene; n n nthe synthetic strategy features a Sharpless asymmetric dihydroxylation (SAD) route to the target compound, using styrene, a readily accessible starting material gives the optically pure dihydroxy compound (ee >97%; the selective monotosylation of primary alcohol, nucleophilic displacement by cyano and subsequent reduction to amino group furnishes the desired 3-phenyl-3-hydroxypropylamine in enatiomerically pure form, a key intermediate in the synthesis of variety of oxetine related anti-depressant drugs.

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优先权日:2008-09-08
标 题 :Coupling of (R)-carbonyl reductase and formate dehydrogenase to promote the synthesis of (R)-phenylethylene glycol

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优先权日:2020-08-13
标题:Alcohol dehydrogenase and coding gene thereof and application of alcohol dehydrogenase in catalytic synthesis of (R) -styrene glycol

专利号:CN-101469318-B
优先权日:2008-09-08
标 题:Coupling of (R)-carbonyl reductase and formate dehydrogenase to promote the synthesis of (R)-phenylethylene glycol

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优先权日:2024-02-20
标题:A method for the enzymatic synthesis of chiral building blocks of halogen alcohol drugs

专利号:NZ-505751-A
优先权日:1997-12-23
标 题:Synthesis of tetrahydroxydiboron esters with acid sensitive alcohols in the presence of a Group VIII metal catalyst