2-乙基己醇置于三溴化磷体系中,化学反应生成4-乙基辛酸 参考文献:Powell; Baldwin,Journal Of The American Chemical Society,1936,Vol. 58,P. 1872 标题:Powell; Baldwin,Journal Of The American Chemical Society,1936,Vol. 58,P. 1872
专利号:EP-2283143-A2 优先权日:2008-06-13 标 题:Enzymatic synthesis of sphingolipids
专利号:WO-2009150022-A2 优先权日:2008-06-13 标题:Enzymatic synthesis of sphingolipids
专利号:US-2022259258-A1 优先权日:2019-06-14 标题:A Manufacturing Process for Peptide and Protein Production 发明人:LUMMISS JUSTIN ALEXANDER MACDONALD; OLLE CHASE R; SHI KEVIN; THOMAS III DALE ARLINGTON 权利人:MYTIDE THERAPEUTICS INC 摘要:The present disclosure provides coupling methods and systems for producing peptides or proteins using semi-continuous or continuous manufacturing techniques to enable rapid production of peptides and proteins using solid phase peptide synthesis (SPPS). The disclosure provides a higher degree of process control for peptide and protein product manufacturing using semi-continuous or continuous manufacturing techniques with inline analytics and automation.
专利号:CN-114524767-B 优先权日:2022-03-11 标 题 :Synthesis method of 5,7-dichloro-1,2,3,4-tetrahydroisoquinoline hydrochloride as intermediate of ritamilast
参考标题:Enantioselective Biomimetic Transamination Of α-Keto Acids Catalyzed By H4-Naphthalene-Derived Axially Chiral Biaryl Pyridoxamines 作者:Chengkang Hou,Guoqing Zhao,Dongfang Xu,Baoguo Zhao |发布日期:2018.3 摘要:Asymmetric Biomimetic Transamination Is A Highly Attractive Method For Synthesis Of Chemically And Biologically Important Chiral Amino Acids And Chiral Amines. Development Of Chiral Pyridoxamines/pyridoxals Is The Key For The Reaction. New Axially Chiral Biaryl Pyridoxamines Based On H4-Naphathene Skeleton Have Been Developed. The Pyridoxamines Display Good Enantioselectivity And High Catalytic Activity