CAS: 2010-61-9; Hexafluoro-2-(4-Methylphenyl)Propan-2-Ol

该化合物是一种有机化合物,其结构复杂,其特点是以甲基和三氟甲基组群取代苯环,以其为代之以苯环;三氟甲基组的存在对其化学特性有重大影响,具有高电子密度和亲脂性,可增强其在有机溶剂中的回作用和溶性;该化合物一般无色至黄色液体或固体,视其纯度和温度而定;在标准条件下,该化合物具有中等稳定性,但可能会发生典型的酒精反应,如氧化或酯化;三氟甲基组还可能影响化合物的沸点和熔点,使其与类似的化合物不同,而没有这些子组分.由于其独特的特性,它可以在各个领域找到应用,包括药物和农业化学物,但具体应用将取决于进一步研究和开发;在处理和接触准则方面,应参考安全数据,因为氟化化合物可能对环境和健康构成风险.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

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CAS号684-16-2 六氟丙酮 | CAS号108-88-3 甲苯 | CAS号106-38-7 对溴甲苯 | CAS号2396-21-6 4-(1,1,1,2,3,3,... | CAS号16261-80-6 4-(2-羟基六氟异丙基)苯甲酸 | CAS号202134-57-4 2-[4-(溴甲基)苯基]-1... | CAS号2396-26-1 4-(七氟异丙基)甲苯

合成工艺路线路线简述

    六氟丙酮,甲苯置于三氯化铝体系中,化学反应生成六氟-2-(对甲苯基)异丙醇
    参考文献:The Electronic Properties Of Fluoroalkyl Groups. Fluorine P-π Interaction1
    标题:The Electronic Properties Of Fluoroalkyl Groups. Fluorine P-π Interaction1
    摘要:
    Doi:10.1021/ja01089A020

    海关参考信息

    专利信息


    专利号:US-8940855-B2
    优先权日:2009-06-02
    标题:Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof
    发明人:HEDRICK JAMES L; NELSON ALSHAKIM; SANDERS DANIEL P
    权利人:IBM
    摘要:A one pot method of preparing cyclic carbonyl compounds comprising an active pendant pentafluorophenyl ester group is disclosed. The cyclic carbonyl compounds can be polymerized by ring opening methods to form ROP polymers comprising repeat units comprising a side chain pentafluorophenyl ester group. Using a suitable nucleophile, the pendant pentafluorophenyl ester group can be selectively transformed into a variety of other functional groups before or after the ring opening polymerization.

    专利号:US-7169955-B2
    优先权日:2000-02-04
    标 题 :Perfluoroisopropylbenzene derivative
    发明人:ONISHI MASANOBU; IKEDA KENICHI; SHIMAOKA TAKASHI; YOSHIDA MASANORI
    权利人:NIHON NOHYAKU CO LTD
    摘要:Perfluoroisopropylbenzene derivatives of the general formula (I) or salts thereof, useful as intermediates or raw materials in the synthesis of various industrial materials including agricultural chemicals, drugs and surfactants: n nwherein X 1 is H, halogen, formyl, optionally halogenated (C 1 –C 6 ) alkyl, (C 1 –C 6 ) alkylthio, or the like; X 2 is H, halogen, formyl, hydroxyl, (C 1 –C 6 ) alkyl, —C(â•?O)—R 1 (wherein R 1 is H, halogen, hydroxyl, (C 1 –C 6 ) alkyl, or NR 2 R 3 , with R 2 and R 3 being each H, C 1-6 alkyl, or the like), or the like; X 3 is H, halogen, hydroxyl, cyano, isocyanate, hydrazino, diazo, —C(â•?O)—R 1 , —SO 2 —R 4 (wherein R 4 is halogen, hydroxyl, (C 1 –C 6 ) alkyl, or NR 5 R 6 , with R 5 and R 6 being each H or (C 1 –C 6 ) alkyl), or the like; and X 4 is H, halogen, (C 1 –C 6 ) alkyl, or (C 1 –C 6 ) alkoxy, with publicly known compounds beingexcepted.

    专利号:US-2012172602-A1
    优先权日:2009-06-02
    标题 :Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof

    专利号:US-8143369-B2
    优先权日:2009-06-02
    标 题 :Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof

    专利号:US-8455612-B2
    优先权日:2009-06-02
    标 题 :Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof

    专利号:US-8450505-B2
    优先权日:2009-06-02
    标 题 :Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof
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    合成参考文献


    参考文献:10.1007/bf00905999
    摘要:Livshits BR, D'yachenko IA, Palii VP, Gambaryan NP. Reactions of polyfluoro ketones with aromatic compounds. Russian Chemical Bulletin. 1967 Mar;16(3):591–5. doi: 10.1007/bf00905999.
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