CAS: 4039-32-1; Lithium Bis(Trimethylsilyl)Amide

上下游产品

CAS号999-97-3 六甲基二硅氮烷 | CAS号109-72-8 正丁基锂 | CAS号96-32-2 溴乙酸甲酯 | CAS号52764-24-6 tetrakis(trimet... | CAS号109-65-9 正溴丁烷 | CAS号50732-21-3 [BIS(TRIMETHYLS... | CAS号38227-87-1 四甲基哌啶锂 | CAS号72525-60-1 hexa-methyldisi... | CAS号881-04-9 9H-fluoren-9-yl... | CAS号33454-82-9 三氟甲磺酸锂 | CAS号45695-56-5 2-嘧啶甲脒 | CAS号57075-81-7 2-氟苄脒盐酸盐 | CAS号1535-67-7 二氟甲基苯基硫 | CAS号17745-52-7 [bis(trimethyls... | CAS号456-56-4 苯基三氟甲基硫醚 | CAS号18243-89-5 2,2'-二硫(六甲基二硅氮烷) | CAS号999-97-3 六甲基二硅氮烷

六甲基二硅氮烷,锂,氢气置于氩,锂体系中,用 正己烷 作为反应溶剂,40.0~225.0 °C,35.55 Kpa 条件下,反应 18.0H,以provided Approximately 150 G Of Lithium Hexamethyldisilazane Solid (Approximately 0.90 Mole,>90% Yield,Total Base Analysis的收率获得产物双三甲基硅基胺基锂
参考文献:Preparation Of Alkali-Metal Hexamethydisilazanes
标题:Preparation Of Alkali-Metal Hexamethydisilazanes
摘要:提供了一种碱金属六甲基二硅氮烷的一步合成方法,其中选择锂,钠和钾等碱金属与1,1,1,3,3,3-六甲基二硅氮烷在反应温度高于碱金属熔点的条件下反应,无需使用电子载体,碱金属衍生试剂(如烷基-芳基有机金属,碱金属酰胺和碱金属氢化物)或催化剂.

专利信息

专利号:US-12012427-B2
优先权日:2019-10-31
标 题 :Synthesis of Fmoc-protected morpholino monomers and their use in the synthesis of morpholino oligomer
发明人：SINHA SURAJIT; KUNDU JAYANTA; GHOSH UJJWAL
权利人:INDIAN ASS FOR THE CULTIVATION OF SCIENCE
摘要:Present invention relates to stable Fmoc protected Morpholino monomers and corresponding oligonucleotides (PMO) and efficient synthesis of the same involving chlorophosphoramidate and H-Phosphonate chemistry. Successful syntheses of the oligonucleotide with higher yield and lesser time have been accomplished employing solid phase synthesis and easy deprotection of Fmoc group with Piperidine.

专利号:US-11548898-B2
优先权日:2017-07-06
标题 :Synthesis of halichondrins
发明人：KISHI YOSHITO; AI YANRAN; YE NING; WANG QIAOYI; YAHATA KENZO; ISO Kentaro; NAINI SANTHOSH REDDY; YAMASHITA SHUJI; LEE JIHOON; OHASHI ISAO; FUKUYAMA TAKASHI
权利人:HARVARD COLLEGE; EISAI R&D MAN CO LTD
摘要:The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

专利号:US-2019047933-A1
优先权日:2016-03-15
标 题:Process for the synthesis of (2e, 4e, 6z, 8e)-8-(3,4-dihydronaphthalen-1(2h)-ylidene)-3,7-dimethylocta-2, 4, 6-trienoic acid
发明人：ABEL ULRICH; RÉPÃ?SI JÓZSEF; Szabó András; SZÃœCSNÉ CSERÉPI STEFÃ?NIA; Bor Ã?dám
权利人:ABEL ULRICH; REPASI JOZSEF; SZABO ANDRAS; SZUECSNE CSEREPI STEFANIA; BOR ADAM; BRICKELL BIOTECH INC
摘要:This invention relates to a novel method for the synthesis of (2E,4E,6Z,8E)-8-(3,4-dihydronaphthalen-1(2H)-ylidene)-3,7-dimethylocta-2,4,6-trienoic acid. In particular, the invention relates to several improvements in several individual steps of the multi-step synthesis scheme

专利号:US-11891351-B2
优先权日:2020-03-20
标 题 :Synthesis of capsaicin derivatives
发明人：LAGER ERIK
权利人:AXICHEM AS
摘要:The present invention relates to the synthesis of capsaicin derivatives, specifically to the synthesis of 6-heptyne derivatives of capsaicin.

专利号:US-2022298204-A1
优先权日:2019-07-05
标题 :Synthesis of a-amanitin and its derivatives
发明人：SIEGERT MARY-ANN; KNITTEL CAROLINE HERTA; SÃœSSMUTH RODERICH
权利人:PURE BIOORGANICS SIA
摘要:The present invention relates to the chemical synthesis of α-amanitin and its derivatives. The present invention also relates to intermediate products of the α-amanitin synthesis.

专利号:US-7825244-B2
优先权日:2005-06-10
标题:Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
发明人：BAINDUR NAND; GAUL MICHAEL DAVID; KREUTTER KEVIN DOUGLAS; XU GUOZHANG
权利人:JANSSEN PHARMACEUTICA NV
摘要:The invention is directed to alkylquinoline and alkylquinazoline compounds of Formula C: n nwherein R 1 , R 2 , R 99 , and X are as defined herein, the use of such compounds in the synthesis of protein tyrosine kinase inhibitors, particularly inhibitors of FLT3 and/or c-kit and/or TrkB.