CAS: 56-35-9; Tributyltin Oxide

该化合物是一种有机锡化合物,其特点是用作海洋涂料中的生物杀灭剂和防污剂;它是一种无色的淡黄色液体,具有独特的气味,以对水生生物的高度毒性著称;三丁基氧化锡具有疏水特性,从而有效地防止了船舶船体和水下结构中的谷仓和其他海洋生物的生长;该化合物在水中溶解性相对较低,但可溶于有机溶剂,这加强了其在各种配方中的应用;由于其环境持久性和生物累积性潜力,三丁基氧化锡在很多国家都面临监管审查和限制;必须谨慎处理这一物质,因为它对健康构成重大风险,包括潜在的内分泌干扰效应;

结构式图片

MSDS等安全信息

欧盟法规

《欧盟PIC法规》REACH注册ECHA物质ECHA物质OtherC&L通报REACH预注册欧盟候选物质清单

上下游产品

tributyltin chloride tributylethynyltin μ-oxobis[(trifluoromethanesulfonato)(phenyl)iodine] β-(cyclohexylthio)ethyl tri-n-butyltin sulfidetributyl(1-chloro-3-phenoxy-2-propanyloxy)stannane Acetic acid (2S,3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-{4-[4-((2S,3R,4S,5R,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-phenylethynyl]-phenoxy}-tetrahydro-pyran-3-yl ester 5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-2-(N-methylcarbamoyl)oxymethyl-1H-imidazole 3-Phenoxycarbonyl-3,4,5,6-tetrahydro-2H-1,3-oxazin-2-one

合成工艺路线路线简述

    Diphenylphosphinigsaeure-Tri-N-Butylstannylester置于naoh体系中,化学反应生成 三丁基氧化锡
    参考文献:Gmelin Handbuch Der Anorganischen Chemie,Gmelin Handbook: Sn: Org.Comp.12,1.4.1.1.1.5.14,Page 215-220
    标题:Gmelin Handbuch Der Anorganischen Chemie,Gmelin Handbook: Sn: Org.Comp.12,1.4.1.1.1.5.14,Page 215-220

    海关参考信息

    专利信息


    专利号:US-9096647-B2
    优先权日:2008-09-16
    标题 :Simplified one-pot synthesis of [18F]SFB for radiolabeling
    发明人:OLMA SEBASTIAN; SHEN CLIFTON KWANG-FU
    权利人:UNIV CALIFORNIA
    摘要:A non-aqueous single pot synthesis of [ 18 F]SFB is set forth. The [ 18 F]SFB produced with this method is then used, for example, to label a peptide or an engineered antibody fragment (diabody) targeting human epidermal growth factor receptor 2 (HER2) as representative examples of labeled compounds for use as an injectable composition to locate abnormal tissue, specifically tumors within an animal or human using a PET scan.

    专利号:US-2010098623-A1
    优先权日:2007-02-07
    标 题 :Zeolite materials and synthesis method thereof
    发明人:GAGEA BOGDAN; JACOBS PIERRE; MARTENS JOHAN; VANDEPITTE HANS
    权利人:GAGEA BOGDAN; JACOBS PIERRE; MARTENS JOHAN; VANDEPITTE HANS
    摘要:The present invention provides zeolites and zeolite-like material having an enhanced microporosity. It was found that such zeolites can be obtained using a zeolite synthesis method comprising the preparation of a gel or solution for the synthesis of a zeolite, said gel or solution comprising appropriate amounts of (i) a conventional monomeric or polymeric silica source and (ii) a molecular template as a microstructuring agent, characterized in that said gel or solution further comprises an organosilane compound having limited self-assembling capacity.

    专利号:US-8987430-B2
    优先权日:2009-10-30
    标 题:Efficient and scalable process for the manufacture of fondaparinux sodium
    发明人:PATEL PAYAL PARTH; MA CHUN; OHRR KEVIN K; NADJI SOURENA
    权利人:PATEL PAYAL PARTH; MA CHUN; OHRR KEVIN K; NADJI SOURENA; RELIABLE BIOPHARMACEUTICAL CORP
    摘要:The present invention relates to a process for the synthesis of the Factor Xa anticoagulent Fondaparinux and related compounds. The invention relates, in addition, to efficient and scalable processes for the synthesis of various intermediates useful in the synthesis of Fondaparinux and related compounds.

    专利号:US-11465129-B2
    优先权日:2017-06-06
    标题:Microwave assisted and low-temperature fabrication of nanowire arrays on scalable 2D and 3D substrates
    发明人:GAO PU-XIAN; LU XINGXU; HOANG SON
    权利人:UNIV CONNECTICUT
    摘要:A method of making a titanium dioxide nanowire array includes contacting a substrate with a solvent comprising a titanium (III) precursor, an acid, and an oxidant while microwave heating the solvent, thereby forming a hydrogen titanate H2Ti2O5.H2O nanowire array. The hydrogen titanate nanowire array is annealed to form a titanium dioxide nanowire array. The substrate is seeded with titanium dioxide before starting the hydrothermal synthesis of the hydrogen titanate nanowire array. The titanium dioxide nanowire array is loaded with a platinum group metal to form an exhaust gas catalyst. The titanium dioxide nanowire array can be used to catalyze oxidation of combustion exhaust.

    专利号:US-2021163438-A1
    优先权日:2017-08-16
    标题 :Synthesis of phytocannabinoids including a demethylation step
    发明人:REEKIE TRISTAN; SCOTT MICHAEL; KASSIOU MICHAEL
    权利人:UNIV SYDNEY
    摘要:A method for demethylating a methylated phytocannabinoid compound of Formula I to form a phytocannabinoid compound of Formula II: Formula I Formula II wherein: R1 is selected from the group consisting of: substituted or unsubstituted C1-C5 alkyl; R2 is selected from the group consisting of: OH or O, and R3 is selected from the group consisting of: a substituted or unsubstituted cyclohexene, a substituted or unsubstituted C2-C8 alkene, or a substituted or unsubstituted C2-C8 dialkene; or R2 is O, and R2 and R3 together form a ring structure in which R2 is an internal ring atom; wherein the method includes: heating a reaction mixture comprising the methylated phytocannabinoid compounds and a polar aprotic solvent in the presence of a dissolved inorganic alkaline salt for a time sufficient to demethylate at least a portion of the methylated phytocannabinoid compounds and form the phytocannabinoid compound.

    专利号:US-6544952-B1
    优先权日:1994-03-15
    标 题:Synthesis of glycoconjugates of the globo-H epitope and uses thereof
    发明人:DANISHEFSKY SAMUEL J; LIVINGSTON PHILIP O; RAGUPATHI GOVINDASWAMI; KIM IN JONG; SCHER HOWARD; SLOVIN SUSAN
    权利人:SLOAN KETTERING INST CANCER
    摘要:The present invention provides a method of synthesizing a compound having the structure:as well as other related glycoconjugates useful as vaccines for inducing antibodies to epithelial cancer cells in an adjuvant therapy therefore, and in a method for preventing recurrence of epithelial cancer. The present invention also provides a vaccine comprising an amount of the compound described above effective to prevent the recurrence of cancer in a subject.
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    合成参考文献


    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
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