专利号:US-2025171686-A1 优先权日:2023-11-27 标题 :Room temperature ambient synthesis of metal-doped halide perovskite nanocrystals 发明人:FELDMANN SASCHA; WUTTIG MATEO CARDENES; VANORMAN ZACHARY 权利人:ECOLE POLYTECHNIQUE FED LAUSANNE EPFL; PRESIDENT AND FELLOWS OF HARVARD COLLEGE CAMBRIDGE MA 摘要:A method of preparing a composition including crystalline particles of a halide perovskite, a composition and a perovskite-based device including the same. The halide perovskite has a chemical formula ABX3, wherein A is a monocation, B is selected from a combination of lead (II) and a dopant and X is selected from a halide.
专利号:US-8252927-B2 优先权日:2008-07-22 标题:Synthesis of substituted 4-amino-pyrimidines 发明人:KARGE REINHARD; LETINOIS ULLA; SHIEFER GERHARD 权利人:KARGE REINHARD; LETINOIS ULLA; SHIEFER GERHARD; DSM IP ASSETS BV 摘要:The present invention is directed to a process for the manufacture of compounds of formula IV wherein R 1 is an amino protecting group, and R 2 is hydrogen or C 1-10 alkyl, comprising a) reacting a compound of formula Ia, wherein M + is a cation, preferably selected from the group consisting of Li + , Na+, K + , ½ Mg 2+ and ½ Zn 2+ , (formula 1 a ) with an ammonium salt NH 4 + X − , wherein X − is an anion, preferably selected from the group consisting of chloride, bromide, sulfate and acetate, in a solvent to a compound of formula II b) reacting a compound of formula II with a nitrile R 2 —CN in the presence of a base to a compound of formula IV. The present invention is further directed to compounds of formula II and their use for the manufacture of vitamin B 1 .
专利号:US-8198443-B2 优先权日:2007-01-19 标题 :Synthesis of 4-amino-pyrimidines scaffolds 发明人:BONRATH WERNER; HAERTER RALPH; KARGE REINHARD; LETINOIS ULLA 权利人:BONRATH WERNER; HAERTER RALPH; KARGE REINHARD; LETINOIS ULLA; DSM IP ASSETS BV 摘要:Process for the manufacture of a compound of the structure (I) with R1=hydrogen, alkyl (C1-C10, linear, cyclic or branched, aliphatic or aromatic), NR′R″ (wherein R′ and R″ are independently selected from H, alkyl [C1-C10, linear, cyclic or branched, aliphatic or aromatic] and R2=CH2R3 wherein R3 is selected from NHR1′″ (with R′″=C(O)H, C(O)CH3, C(O)alkyl, CH2C6H2(OMe)3 or other saponifiable residues), alkyl (C1-C10, linear, cyclic or branched) aromatic residues, heteroaryl residues, substituted aryl residues, e.g. 3,4,5-trimethoxy-phenyl) wherein 1 equivalent of an α-formyl-propionitrile salt is reacted with 0.75 to 2 equivalents of an acetamidine salt in the presence of a Lewis acid.
专利号:EP-1163230-B1 优先权日:1999-03-08 标题 :Formamidine sulfate and phosphate salts, their production and their use in the synthesis of 1,3,5-triazine 发明人:GUETHNER THOMAS; KRAMMER DORIS; GRAML BERND 权利人:DEGUSSA 摘要:The invention relates to the use of formamidine salts of the general formula (I): (NH2-CH=NH2)nHx-nY, where Y is SO4, x is 2 and n is between 0.1 and 2.0, or Y is PO4, x is 3 and n is between 0.1 and 3.0. The salts obtained in accordance with the invention are especially easy to prepare from the technical perspective and make it possibly to produce high yields of highly pure 1,3,5-triazine by thermal decomposition of the corresponding formamidine salts.
专利号:US-12415828-B2 优先权日:2014-08-22 标题:Modified oligonucleotides and methods for their synthesis 发明人:STETSENKO DMITRY; KUPRYUSHKIN MAXIM; PYSHNYI DMITRII 权利人:NOOGEN LLC 摘要:Modified oligonucleotides that contain one or more of the phosphate groups substituted at phosphorus and methods for their synthesis are disclosed.
专利号:US-2009069334-A1 优先权日:2007-08-18 标题:Pyridazine based alpha-helix mimetics 发明人:REBEK JR JULIUS; BIROS SHANNON; MOISAN LIONEL; VOLONTERIO ALESSANDRO; MANN ENRIQUE; DALE TREVOR 权利人:SCRIPPS RESEARCH INST 摘要:The synthesis of new α-helix scaffolds mimicking i, i+3 or i+4, i+7 residues, was accomplished. The common pyridazine heterocycle originates from the easily available building block, 6. These scaffolds may be thought of as synthetic counterparts of amphiphilic α-helices having a “wet faceâ€? along one side and a hydrophobic face along the other side of the helix.
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