专利号:US-5219988-A 优先权日:1989-02-22 标 题 :Gem-diamino derivatives and their use in the synthesis of retro-inverso peptides 发明人:GAZERRO LAURA; PINORI MASSIMO; VERDINI ANTONIO S 权利人:ENIRICERCHE SPA; SCLAVO SPA 摘要:This invention relates to new gem-diamino derivatives of general formula (I) ##STR1## where R is the side chain of an amino acid, of which any functional groups are suitably protected, and n X is an acyl group chosen from the group consisting of 2-nitrobenzoyl, 4-chloro-butyryl, acetoacetyl, 4-bromo-butyryl, (2-nitrophenoxy)-acetyl and 2-methyl-2-(2'-nitro-phenoxy)propionyl, of use in introducing gem-diamino residues into retro-inverso peptides. The invention further relates to a method for the synthesis of retro-inverso peptides in which the gem-diamino residue or residues are introduced using the new compound (I).
专利号:US-4866175-A 优先权日:1966-11-08 标 题 :Novel process for the synthesis of quinoxaline and benzimidazole-N-oxides 发明人:ISSIDORIDES COSTAS H; HADDADIN MAKHLUF J 权利人:RESEARCH CORP 摘要:The synthesis of quinoxaline and benzimidazole-N-oxides and of ester amd amide derivatives of 3-hydroxy-2-quinoxalinecarboxylic acid by a movel process consisting of the reaction between a benzofuroxan and an activated methylene-containing compound under basic conditions.
专利号:US-7723539-B2 优先权日:2004-06-16 标题:Catalysts based on metal complexes for the synthesis of optically active chrysanthemic acid 发明人:CARLONI SILVIA; BORZATTA VALERIO; MORONI LENI; TANZI GIADA; SARTORI GIOVANNI; MAGGI RAIMONDO 权利人:ENDURA SPA 摘要:Catalysts are described based on metal complexes derived from optically active s compounds, chosen from the classes consisting of bisoxazolines and salicylaldimines supported on an organic or inorganic matrix and employed in particular for the synthesis of optically active chrysanthemic acid.
专利号:US-8709129-B2 优先权日:2009-07-21 标题 :Compounds useful as ligands of actinides, their synthesis and their uses 发明人:MARIE CÉCILE; MIGUIRDITCHIAN MANUEL; BISSON JULIA; GUILLANEUX DENIS; DUBREUIL DIDIER 权利人:MARIE CÉCILE; MIGUIRDITCHIAN MANUEL; BISSON JULIA; GUILLANEUX DENIS; DUBREUIL DIDIER; COMMISSARIAT ENERGIE ATOMIQUE 摘要:The invention relates to novel compounds which are useful as ligands of actinides, to the synthesis of these compounds and to their uses. n These compounds fit the general formula (I) hereafter: n nwherein R 1 and R 2 , either identical or different, represent H, a linear or branched, saturated or unsaturated C 1 -C 12 hydrocarbon group, a phenyl, benzyl, diphenyl or tolyl group; R 3 represents H, a linear or branched, saturated or unsaturated C 1 -C 12 hydrocarbon group, a phenyl, tolyl or linear or branched C 1 -C 12 alkoxy group; while R 4 represents H, a linear or branched, saturated or unsaturated C 1 -C 12 hydrocarbon group, a phenyl or tolyl group.n n Field of applications: the processing of used nuclear fuels via a hydrometallurgical route.
专利号:US-6881847-B2 优先权日:2001-02-01 标题:Process for the synthesis and recovery of nitramines 发明人:HIGHSMITH THOMAS K; HANKS JAMI M; VELARDE STEPHEN P; BOTTARO JEFFREY 权利人:ALLIANT TECHSYSTEMS INC 摘要:A method is provided for the synthesis of nitramines and the recovery of the nitramines from a clathrate.
专利号:US-7038037-B2 优先权日:2002-06-20 标题 :Method for sequential support-bound synthesis of conjugated oligomeric compounds 发明人:MAIER MARTIN A; GUZAEV ANDREI P; MANOHARAN MUTHIAH 权利人:ISIS PHARMACEUTICALS INC 摘要:A sequential support-bound synthesis method is disclosed for preparing a conjugated oligomeric compound, preferably a PNA-peptide conjugate or an oligonucleotide-peptide conjugate, using a bridging molecule having at least two N-protecting amino groups. A conjugated oligomeric compound for therapeutic or prophylactic delivery is also disclosed.
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合成参考文献
摘要:Silva, V. L. M.; Pinto, D. C. G. A.; Santos, C. M. M.; Rocha, D. H. A., Science of Synthesis Knowledge Updates, (2022) 3, 206. 摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 147. 摘要:Biochemical Journal., 34(1196), 1940 参考文献:10.1107/s1600536810044089 摘要:Gowda BT, Tokarčík M, Rodrigues VZ, Kožíšek J, Fuess H. N,N′-Bis(3-methylphenyl)propanediamide. Acta Crystallogr E Struct Rep Online. 2010 Oct 31;66(11):o3037. doi: 10.1107/s1600536810044089. 参考文献:10.1016/j.jhazmat.2008.04.093 摘要:Ansari SA, Mohapatra PK, Manchanda VK. A novel malonamide grafted polystyrene-divinyl benzene resin for extraction, pre-concentration and separation of actinides. J Hazard Mater. 2009 Jan 30;161(2-3):1323–9. doi: 10.1016/j.jhazmat.2008.04.093.