CAS: 4495-66-3; 1-(4-(Benzyloxy)Phenyl)Propan-1-One

上下游产品

CAS号100-39-0 溴化苄 | CAS号70-70-2 4-羟基苯丙酮; 对羟基苯丙酮 | CAS号87030-16-8 (E)-(benzyloxy)... | CAS号56-93-9 苄基三甲基氯化铵 | CAS号100-44-7 氯化苄 | CAS号637-27-4 丙酸苯酯 | CAS号141-52-6 乙醇钠 | CAS号111000-54-5 2-chloro-1-(4-p... | CAS号35081-45-9 1-[4-(苄氧基)苯基]-2... | CAS号198479-82-2 ethyl 2-[4-[[3-... | CAS号198479-63-9 3-甲基-5-苄氧基-2-(4... | CAS号198481-32-2 1-[[4-[2-(氮杂环庚烷... | CAS号70-70-2 4-羟基苯丙酮; 对羟基苯丙酮 | CAS号35133-39-2 1-[4-(phenylmet... | CAS号198480-21-6 1-[4-(2-(氮杂环庚烷-... | CAS号62437-05-2 5-methyl-4-(4-p... | CAS号62634-51-9 2-(benzylamino)...

4'-苯甲氧基-2-溴苯丙酮置于高氯酸四乙基铵,三乙胺体系中,用 乙醇,二甲基亚砜 作为反应溶剂,化学反应 4.0H,以87%的收率获得产物4'-苄氧基苯丙酮
参考文献:A Facile And Versatile Electro-Reductive System For Hydrodefunctionalization Under Ambient Conditions
标题:A Facile And Versatile Electro-Reductive System For Hydrodefunctionalization Under Ambient Conditions
摘要:描述了一种使用三乙胺作为牺牲还原剂的简便电还原去功能化系统,通过简单地改变反应溶剂,可以方便地切换还原的选择性和能力.
DOI:10.1039/d1Gc00317H

专利信息

专利号:US-7968732-B1
优先权日:2010-09-07
标 题 :Process for the preparation of 5-benzyloxy-2-(4-benzyloxyphenyl)-3-methyl-1H-indole
发明人：DIVI MURALI KRISHNA PRASAD; RAO BOLINENI NAGESWARA; SURESH DANDU VENKATA
权利人:DIVIS LAB LTD
摘要:The present invention is related to a process for the preparation of 5-benzyloxy-2-(4-benzyloxyphenyl)-3-methyl-1H-Indole (formula-1, a useful intermediate for the synthesis of bazedoxifene) using 4-benzyloxy propiophenone and 4-benzyloxy phenyl hydrazine hydrochloride.

专利号:US-10844047-B2
优先权日:2018-06-21
标题:Process for the preparation of bazedoxifene
发明人：FERRARI MASSIMO; ZANI DANIELE DE; VEZZOSI STEFANO; BELOTTI PAOLO
权利人:ERREGIERRE SPA
摘要:The invention relates to a process for preparation of the compound 3-methyl-5-benzyloxy-2-(4-benzyloxyphenyl)-1H-indole 5, an intermediate for the synthesis of bazedoxifene and bazedoxifene acetate.

专利号:EP-1025077-B1
优先权日:1997-10-15
标题 :Novel aryloxy-alkyl-dialkylamines
发明人：RAVEENDRANATH PANOLIL; ZELDIS JOSEPH; VID GALINA; POTOSKI JOHN RICHARD; REN JIANXIN
权利人:WYETH CORP
摘要:The present invention provides compounds useful in the synthesis of biologically active compounds, and processes for their production, the compounds having formula (I) wherein: R?1 and R2¿ are, independently, selected from H; C¿1?-C12 alkyl or C1-C6 perfluorinated alkyl; X represents a leaving group; A is O or S; m is an integer from 1 to 3, preferably 2; R?3, R4, R5, and R6¿ are independently selected from H, halogen, -NO¿2?, alkyl, alkoxy, C1-C6 perfluorinated alkyl, OH or the C1-C4 esters or alkyl ethers thereof, -CN, -O-R?1¿, -O-Ar, -S-R1, -S-Ar, -SO-R1, -SO-Ar, -SO¿2?-R?1, -SO¿2-Ar, -CO-R1, -CO-Ar, -CO¿2-R?1, or -CO¿2?-Ar; and Y is selected from a) the moiety (i) wherein R7 and R8 are independently selected from the group of H, C1-C6 alkyl, or phenyl; or b) an optionally substituted five-, six- or seven-membered saturated, unsaturated or partially unsaturated heterocycle or bicyclic heterocycle containing up to two heteroatoms selected from the group consisting of -O-, -NH-, -N(C1C4 alkyl)-, -N=, and -S(O)n-.

专利号:US-6268504-B1
优先权日:1997-10-15
标题 :Aryloxy-alkyl-dialkylamines
发明人：RAVEENDRANATH PANOLIL; ZELDIS JOSEPH; VID GALINA; POTOSKI JOHN R; REN JIANXIN; IERA SILVIO
权利人:AMERICAN HOME PROD
摘要:The present invention provides compounds useful in the synthesis of biologically active compounds, and processes for their production, the compounds having the formula:wherein: R1 and R2 are, independently, selected from H; C1-C12 alkyl or C1-C6 perfluorinated alkyl; X represents a leaving group; A is O or S; m is an integer from 1 to 3, preferably 2; R3, R4, R5, and R6 are independently selected from H, halogen, -NO2, alkyl, alkoxy, C1-C6 perfluorinated alkyl, OH or the C1-C4 esters or alkyl ethers thereof, -CN, -O-R1, -O-Ar, -S-R1, -S-Ar, -SO-R1, -SO-Ar, -SO2-R1, -SO2-Ar, -CO-R1, -CO-Ar, -CO2-R1, or -CO2-Ar; and Y is selected from a) the moiety:wherein R7 and R8 are independently selected from the group of H, C1-C6 alkyl, or phenyl; or b) an optionally substituted five-, six- or seven-membered saturated, unsaturated or partially unsaturated heterocycle or bicyclic heterocycle containing up to two heteroatoms selected from the group consisting of -O-, -NH-, -N(C1C4 alkyl)-, -N=, and -S(O)n-.