CAS: 513-36-0; 1-Chloro-2-Methylpropane

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CAS号78-83-1 异丁醇 | CAS号543-27-1 氯甲酸异丁酯 | CAS号78-77-3 溴代异丁烷 | CAS号75-28-5 异丁烷 | CAS号10026-13-8 五氯化磷 | CAS号113223-50-0 (1-naphthyl)(ph... | CAS号78-81-9 异丁胺 | CAS号513-38-2 碘代异丁烷 | CAS号115-11-7 2-甲基丙烯 | CAS号1221-65-4 1,6-Di-t-butyl-... | CAS号1081-32-9 6-tert-butylnap... | CAS号624-38-4 1,4-二碘苯 | CAS号35779-04-5 1-叔丁基-3-碘苯 | CAS号3972-56-3 1-叔丁基-4-氯苯 | CAS号3972-65-4 对叔丁基溴苯 | CAS号585-34-2 3-叔丁基苯酚 | CAS号88-18-6 邻叔丁基苯酚 | CAS号376348-67-3 N-(8-苄基-8-氮杂双环[... | CAS号507-20-0 氯代叔丁烷

Chlorosulfurous Acid Isobutyl Ester置于zinc(II) Chloride体系中,化学反应生成 氯代异丁烷
参考文献:Goldfarb; Smorgonski,Izvestiya Akademii Nauk Sssr,Seriya Khimicheskaya,1936,P. 557
标题:Goldfarb; Smorgonski,Izvestiya Akademii Nauk Sssr,Seriya Khimicheskaya,1936,P. 557

专利信息

专利号:US-9126995-B2
优先权日:2011-11-08
标题:Method for catalytic asymmetric synthesis of optically active isoxazoline compound and optically active isoxazoline compound
发明人：TOYAMA KEN-ICHI; MORIYAMA YUJI; MATOBA KAZUTAKA; YAOSAKA MANABU; IKEDA EITATSU
权利人:NISSAN CHEMICAL IND LTD
摘要:There is provided a method for catalytic asymmetric synthesis of optically active isoxazoline compound and an optically active isoxazoline compound. A method for catalytic asymmetric synthesis of optically active isoxazoline compound of a formula (6) including reacting an α,β-unsaturated carbonyl compound of a formula (1) and a hydroxylamine in a solvent in the presence of a base by adding a chiral phase transfer catalyst. An optically active isoxazoline compound of a formula (13) that can be synthesized by the method.

专利号:US-7173059-B2
优先权日:2003-05-08
标题:Intermediates useful in the synthesis of HIV-protease inhibitors and methods for preparing the same
发明人：ALBIZATI KIM FRANCIS; BABU SRINIVASAN
权利人:AGOURON PHARMA
摘要:Optically active 3-amino-butene and 1,2-dihydroxy-3-amino-butane intermediate compounds, useful in the synthesis of HIV-protease inhibitors and methods of preparing these intermediate compounds are disclosed.

专利号:US-6472534-B2
优先权日:1999-10-21
标 题:Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors
发明人：BORER BENNETT C; ZOOK SCOTT E; BUSSE JULIETTE K
权利人:AGOURON PHARMA
摘要:Methods for the preparation of chemical intermediates in the synthesis of HIV-protease inhibitors related to and including nelfinavir mesylate are disclosed. The method of this invention comprises converting tetrohydran derivatives into oxazolines to provide key reaction intermediates for the preparation of nelfinavir. Also disclosed is a method for the preparation of a chiral amino alcohol from an epoxy-tetrahydrofuran.

专利号:US-11766432-B2
优先权日:2018-07-27
标题 :Cleavable conjugates of catechol compounds and water-soluble polymers and methods of treatment using the same
发明人：BENTLEY MICHAEL; FANG ZHIHAO; WEIMER REBECCA; VIEGAS TACEY; MOREADITH RANDALL
权利人:SERINA THERAPEUTICS INC
摘要:Described are conjugates comprising a water-soluble polymer linked to a compound comprising a catechol moiety via a cleavable linkage, wherein the cleavable linkage is formed between the water-soluble polymer and a first phenolic hydroxyl group of the catechol moiety and a second phenolic hydroxyl group of the catechol moiety is linked to a blocking group wherein the rate of hydrolytic release of the compound comprising the catechol moiety is controlled, at least in part, through structure or design of the blocking group on the second phenolic hydroxyl group of the catechol moiety. Therefore, the rate of hydrolytic release of the compound comprising the catechol moiety can be tuned through structural design of the group on the second phenolic hydroxyl group of the catechol moiety. Compounds used in the synthesis of the described conjugates and methods of using the described conjugate and other compounds in the treatment of dopamine-responsive disorders are also described.

专利号:US-10913702-B2
优先权日:2018-01-15
标 题:Method for cycloaddition of dimethyl muconate
发明人：PARK JAE KYUN; PARK JEONG HO; CHAE HEE-IL
权利人:SK CHEMICALS CO LTD
摘要:A method for cycloaddition of dimethyl muconate is disclosed. According to the method, a direct transferring of a solid phase trans,trans-dimehtyl muconate into a reactor pre-filled with ethylene gas increases the efficiency of the reaction and suppress side reactions resulting an improvements in yield and purity. Furthermore, the method is capable of obtaining a high yield of dimethylcyclohex-2-en-1,4-dicarboxylate at a lower cost, and therefore is also useful for the mass synthesis of dimethyl terephthalate.

专利号:US-4895954-A
优先权日:1986-07-26
标题 :Precursors for synthesis of triphendioxazine dyestuffs
发明人：SCHWAIGER GUENTHER; SPRINGER HARTMUT; HELMLING WALTER
权利人:HOECHST AG
摘要:Water-soluble triphendioxazine compounds which have fiber-reactive properties as dyestuffs, which afford deep and fast dyeings on fiber materials, such as wool and, in particular, cellulose, and which correspond to the formula (1) ##STR1## in which: n is the number 0 or 1; n Y is the vinyl group or an ethyl group containing, in β-position, a substituent which can be eliminated by means of an alkali; n Q 1 and Q 2 both represent a benzotriazole radical which can also be additionally substituted in the benzene nucleus by alkyl having 1 to 4 carbon atoms, alkoxy having 1 to 4 carbon atoms, halogen, carboxy or sulfo; n B is --O--, --S--, --NH-- or --N(R')-- wherein R' is optionally substituted alkyl having 1 to 6 carbon atoms; n W 1 and W 2 both represent a divalent, optionally substituted aliphatic, cycloaliphatic, aliphatic-cycloaliphatic, araliphatic or aromatic-carbocyclic radical, it being possible for the aliphatic radicals to be interrupted by hetero groups --O--, --S--, --SO 2 --, --CO--, 1,4-piperidino, --NH-- and/or --N(R o )-- in which R o is optionally substituted alkyl having 1 to 6 carbon atoms or alkanoyl having 2 to 5 carbon atoms, and/or for aliphatic and aryl radicals to be attached to one another through such a hetero group; n R is hydrogen, alkyl having 1 to 6 carbon atoms, alkoxy having 1 to 6 carbon atoms, halogen, carboxyl or sulfo; n E is hydrogen, sulfo, carboxyl, a group --SO 2 --Y as defined above or an optionally substituted sulfonamide group; and n X 1 and X 2 are both hydrogen or halogen, cycloalkyl, alkoxy, aryloxy, aryl or another substituent; n and at least one carboxy, sulfo or sulfato group is present in the molecule (1), n and pre-products of those triphendioxazine compounds, of the general formula ##STR2## in which K is an amino or nitro group, Y' is β-hydroxyethyl or defined as for Y, W has one of the meanings of W 1 , and E' is hydrogen, sulfo, carboxy or a group of the formula --SO 2 --Y' defined above, or an optionally substituted sulfonamide group, and R, B and R* have the above meanings.