CAS: 56999-16-7; 2-(2,2-Diethoxyethoxy)-1,1-Diethoxyethane

相似化合物

98166-29-1 621-63-6 94158-44-8

上下游产品

ethanol 2,2'-oxybis(acetaldehyde) bis-(2,2-bis-ethylsulfanyl-ethyl) ether Bromoacetaldehyde diethyl acetal 9-methyl-3-oxa-9-aza-bicyclo[3.3.1]nonan-7-one nonan-3-oneN-benzyl-7-oxa-9-azabicyclo3.3.1nonan-3-one

2-溴-1,1-二乙氧基乙烷,2,2-二乙氧基乙醇置于sodium Hydride体系中,用 Xylene 作为反应溶剂,化学反应 2.0H,以42%的收率获得产物2-(2,2-二乙氧基乙氧基)-1,1-二乙氧基乙烷
参考文献: Bicyclic Piperidine Derivatives As Antagonists Of The Ccr1 Chemokine Receptor[fr] Derives De Piperidine Bicycliques Utilises Comme Antagonistes Du Recepteur De Chimiokine Ccr1
标题: Bicyclic Piperidine Derivatives As Antagonists Of The Ccr1 Chemokine Receptor[fr] Derives De Piperidine Bicycliques Utilises Comme Antagonistes Du Recepteur De Chimiokine Ccr1
摘要:一种具有如上所定义的a,B,C,R1,R2,R3,R4,R5,R6,Q,W,Y和z的化合物,用作mip-1α(ccl3)与其受体ccr1结合的有效且选择性抑制剂,该受体存在于炎症和免疫调节细胞上(最好是白细胞和淋巴细胞).

专利信息

专利号:US-5139940-A
优先权日:1989-10-26
标题 :Activation compounds and methods of synthesis of activation compounds
发明人：ISAACS STEPHEN T; CIMINO GEORGE D; METCHETTE KENNETH C; TESSMAN JOHN W
权利人:ISAACS STEPHEN T; CIMINO GOERGE D; METCHETTE KENNETH C; TESSMAN JOHN W
摘要:The invention is directed to isopsoralen compound compositions that contain a variety of substitutions which yet permit their binding to nucleic acid polymers. Reaction conditions that activate these bound isopsoralens results in covalent crosslinking to the nucleic acid polymers. The resultant complex is inhibited from being a template for the template-directed enzymatic synthesis of a complementary nucleic acid polymer. Beside the isopsoralens compositions, the invention includes their synthesis, the nucleic acid complex production and detection, and the above inhibitory method of use of the isopsoralens.