专利号:US-11466283-B2 优先权日:2016-08-18 标 题:Plants and methods for increasing and decreasing synthesis of cannabinoids 发明人:ROSCOW ROBERT F 权利人:CANOPY GROWTH CORP 摘要:This disclosure relates to new plants and methods for increasing and decreasing synthesis of cannabinoids. The plants disclosed herein comprise unnatural ratios and concentrations of cannabinoids in plants of genus Cannabis . The methods disclosed herein comprise manipulating the biosynthetic pathway of cannabinoids to produce plants of genus Cannabis with unnatural ratios and concentrations of cannabinoids.
专利号:US-2017268027-A1 优先权日:2014-12-22 标题:Method for synthesis of fatty acids 发明人:CESCUT JULIEN; URIBELARREA JEAN-LOUIS; GUILLOUET STEPHANE; MOLINA-JOUVE CAROLE; SAGNAK RANA 权利人:INST NAT DES SCIENCES APPLIQUEES DE TOULOUSE; CENTRE NAT RECH SCIENT; AGRONOMIQUE INST NAT RECH; FIDOP (FONDS DE DEV DES FILIERES DES OLEAGINEUX ET DES PROTEAGINEUX) 摘要:Disclosed is a method for synthesis of fatty acids by culturing a eukaryotic microorganism from the fungi kingdom, that is naturally oleaginous or rendered oleaginous. The culture is performed in the presence a fatty acid synthase inhibitor in the culture medium.
专利号:US-2012094919-A1 优先权日:2009-03-16 标题 :Use of tripeptides 发明人:GRAEUB REMO; HEIDL MARC; IMFELD DOMINIK; MUELLER EIKE; WIKSTROEM PETER; ZIEGLER HUGO 权利人:GRAEUB REMO; HEIDL MARC; IMFELD DOMINIK; MUELLER EIKE; WIKSTROEM PETER; ZIEGLER HUGO 摘要:The present invention relates to the use of tripeptide derivatives for tightening, firming and/or moisturizing skin. Furthermore, the invention relates to a method for stimulating the synthesis of glycosaminoglycans containing a D-glucosamine and/or N-acetyl-D-glucosamine residue and/or proteoglycans by fibroblasts and/or keratinocytes such as in particular the synthesis of Hyaluronic acid and/or of the proteoglycans Decorin and/or Lumican.
专利号:US-2002165207-A1 优先权日:2001-05-02 标题 :Compositions and methods for the treatment of diabetic neuropathy 发明人:ROSENBLOOM RICHARD 摘要:Compositions and a method for the treatment of diabetic neuropathy is disclosed. The compositions comprise a mixture of a compound that promotes synthesis of nerve growth factor, an aldose reductase inhibitor and an antioxidant, optionally formulated in a pharmaceutically acceptable carrier. This combination of active agents provides significant, effective relief of the symptoms of diabetic neuropathy, as well as at least partial recovery of lost neurological function in some cases. In addition, the compositions of the present invention, when used in effective amounts to treat diabetic neuropathy, do not exhibit the severe side effects of many prior art compositions proposed for treatment of this ailment. n In a second aspect, a method for the administration of a composition in accordance with the present invention for the treatment of diabetic neuropathy is disclosed. In the method, an effective amount of the composition of the invention is administered on a regular basis over a period of time sufficient to provide the beneficial effects of relief from the symptoms of diabetic neuropathy, as well as at least some recovery of the damaged nerve tissues.
专利号:US-6051383-A 优先权日:1995-06-26 标题:Sequences for production of 2,4-diacetylphloroglucinol and methods 发明人:THOMASHOW LINDA S; BANGERA MAHALAXMI; WELLER DAVID M; COOK R JAMES 权利人:US AGRICULTURE; UNIV WASHINGTON 摘要:DNA sequences which function specifically in the synthesis of 2,4-diacetylphloroglucinol (Phl) are described. The sequences include phl genes which encode phl gene proteins and coding and regulatory sequences for production of Phl as well as sequences containing phl genes, which sequences have the capability of conferring or enhancing Phl biosynthetic capability in bacterial strains. The transformed strains are useful as biocontrol agents against fungal pathogens.
专利号:US-9688611-B2 优先权日:2015-10-21 标 题:Synthesis of (S)-2-acetamido-3-(4-hydroxy-3-(3-methylbut-2-enyl) phenyl) propanoic acid derivatives 发明人:MANSHA Muhammad; ABBAS YASIR; ULLAH NISAR 权利人:UNIV KING FAHD PET & MINERALS 摘要:A method for producing a compound of formula (I) or a pharmaceutically acceptable salt, solvate, tautomer or stereoisomer, such as compound 1 and compound 2 is disclosed. The method proceeds through an O-allylated tyrosine-based compound, such as compound 3 and preferably comprises [3,3] sigmatropic Claisen rearrangement and olefin cross metathesis reactions. In addition, a pharmaceutical composition comprising a compound of formula (I) a tumor necrosis factor (TNF) related apoptosis inducing ligand (TRAIL) and a pharmaceutically acceptable carrier or excipient is disclosed.
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合成参考文献
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