CAS: 2545-40-6; 2-Acetamidosuccinic Acid

该化合物是一种自然产生的氨酸衍生物,具体来说是一种乙酰形式的甲酸,其特征是分子式,包括碳,氢,氮和氧原子.NAA是一种白色晶状固体,在水中可溶解,并由于存在碳oxylic酸组而表现出微酸性质.该化合物在各种生物过程,特别是在中央...

结构式图片

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CAS号56-84-8 L-天门冬氨酸 | CAS号108-24-7 乙酸酐 | CAS号463-51-4 乙烯酮 | CAS号617-45-8 DL-天门冬氨酸 | CAS号41148-79-2 N-(2,5-二氧代氧杂戊环-... | CAS号56-84-8 L-天门冬氨酸 | CAS号5429-56-1 2-乙酰氨基丙烯酸 | CAS号3397-54-4 (1)-N-(Tetrahyd... | CAS号1783-96-6 D-天门冬氨酸 | CAS号77693-09-5 N-(2,5-dioxo-1-...

合成工艺路线路线简述

    在 Sodium Hydroxide体系中,用83%的收率获得n-乙酰-Dl-天冬氨酸
    参考文献:Kolodziejczyk,Aleksander M.; Arendt,Anatol,Polish Journal Of Chemistry,1980,Vol. 54,# 6,P. 1327-1329
    标题:Kolodziejczyk,Aleksander M.; Arendt,Anatol,Polish Journal Of Chemistry,1980,Vol. 54,# 6,P. 1327-1329

    海关参考信息

    专利信息


    专利号:US-4314939-A
    优先权日:1979-07-13
    标题 :Process for the preparation of 15-hydroxyimino-E-homoeburnane and intermediates therefor
    发明人:SZANTAY CSABA; SZABO LAJOS; KALAUS GYOERGY; DANCSI LAJOS; KEVE TIBOR; DREXLER FERENC
    权利人:RICHTER GEDEON VEGYESZET
    摘要:A process for the preparation of 15-hydroxyimino-E-homoeburnane derivatives of the formula (I), ##STR1## wherein X 1 stands for hydrogen or halogen and n R is a C 1-6 alkyl group, n or acid addition salts and optically active derivatives thereof. These compounds are valuable intermediates of the synthesis of compounds with outstanding biological effects. According to the invention a racemic or optically active 15-hydroxy-E-homoeburnane derivative of the formula (II), ##STR2## is treated, optionally after separating the 15-epimers and/or resolution, with a halogenating agent. The resulting 15-halo-E-homoeburnane derivative of the formula (III), ##STR3## wherein X 2 stands for halogen, is reacted, optionally after separating the 15 epimers and/or resolution, with an alkali nitrite in the presence of an acid, and, if desired, the resulting 15-hydroxyimino-E-homoeburnane derivative of the formula (I) is converted into its acid addition salt and/or resolved. The compounds of the formula (III) formed as intermediates in the above process are new and biologically active.

    专利号:US-2009111737-A1
    优先权日:1999-05-24
    标题:Novel antibacterial agents
    发明人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
    权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
    摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

    专利号:US-2024400861-A1
    优先权日:2021-10-01
    标题 :Triazole- And/Or Triazolium-Based Polymers And Copolymers As Additives For Chemical Mechanical Planarization Slurries
    发明人:LARBIG GREGOR; KIRSCH PEER; HENGST MATTHIAS; SHI XIAOBO; STENDER MATTHIAS
    权利人:VERSUM MAT US LLC
    摘要:Synthesis of triazole- and/or triazolium-based polymers is disclosed. Chemical Mechanical Planarization (CMP) slurries comprise abrasives; activator; oxidizing agent; additive comprising triazole- and/or triazolium-based polymers; and water. The use of the synthesized triazole- and/or triazolium-based polymers in the CMP slurries reduces dishing and erosion in highly selective tungsten slurries.

    专利号:WO-9209300-A1
    优先权日:1990-11-21
    标 题:Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures

    专利号:WO-2024073211-A1
    优先权日:2022-09-29
    标题:Guanidinium-based polyionic liquids and their use as additives for chemical mechanical planarization slurries
    发明人:LARBIG GREGOR; KIRSCH PEER; SHI XIAOBO
    权利人:VERSUM MAT US LLC
    摘要:Synthesis of guanidinium-based polymers is disclosed. Chemical Mechanical Planarization (CMP) slurries comprise abrasives; activator; oxidizing agent; additive comprising guanidinium-based polymers; and water. The use of the synthesized guanidinium-based polymers in the CMP slurries reduces dishing and erosion in highly selective tungsten slurries.

    专利号:US-2025215130-A1
    优先权日:2022-04-11
    标 题:Polycationic Polymer Or Copolymer Having Different Cation Types For Slurries In Chemical Mechanical Planarization
    发明人:LARBIG GREGOR; SHI XIAOBO
    权利人:MERCK PATENT GMBH; VERSUM MAT US LLC
    摘要:Synthesis of polycationic polymer or copolymer is disclosed. The polycationic polymer or copolymer are formed by at least one first cationic monomer and at least one second cationic monomer wherein the first cationic monomer and the second cationic monomer have different cationic groups; such as imidazolium group and non-imidazolium group. Chemical Mechanical Planarization (CMP) slurries comprise abrasives; activator; oxidizing agent; additive comprising polycationic polymer or copolymer; and water are also disclosed. The use of the synthesized polycationic polymer or copolymer in the CMP slurries reduces dishing and erosion in highly selective tungsten slurries.
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