CAS: 630-18-2; Pivalonitrile

相似化合物

75-98-9 754-10-9 630-19-3

上下游产品

CAS号630-19-3 三甲基乙醛 | CAS号637-91-2 新戊醛肟 | CAS号3282-30-2 特戊酰氯 | CAS号754-10-9 三甲基乙酰胺 | CAS号143-33-9 氰化钠 | CAS号75-65-0 叔丁醇 | CAS号10442-39-4 氰化四丁基胺 | CAS号507-20-0 氯代叔丁烷 | CAS号7677-24-9 三甲基氰硅烷 | CAS号10526-16-6 Hexanedinitrile... | CAS号19295-57-9 3-羟基-2,2-二甲基丙腈 | CAS号101268-22-8 1-(4-甲苯磺酰基)-3,3... | CAS号38222-83-2 2,6-二叔丁基-4-甲基吡啶 | CAS号42956-75-2 N-羟基新戊酰胺 | CAS号184243-13-8 4,6-ditert-buty... | CAS号22583-66-0 1-(4-(叔丁基)苯基)-2... | CAS号938-16-9 2-甲基丙酮 | CAS号630-19-3 三甲基乙醛

特戊醛置于氧气,铜,氯化铵体系中,用 吡啶 作为反应溶剂,化学反应 24.0H,以90%的收率获得产物三甲基乙腈
参考文献:Simple And Efficient Copper-Catalyzed One-Pot Conversion Of Aldehydes Into Nitriles
标题:Simple And Efficient Copper-Catalyzed One-Pot Conversion Of Aldehydes Into Nitriles
摘要:芳香族,杂环以及叔级脂肪族腈类化合物可以通过相应的醛与吡啶中的氯化铵/铜粉/氧气体系反应制备.这一新型单瓶工艺能以极高的收率甚至定量地得到纯净的腈类化合物.
DOI:10.1055/s-1989-27285

专利信息

专利号:US-4938940-A
优先权日:1988-01-14
标 题:Vapor-phase method for synthesis of diamond
发明人：HIROSE YOICHI; KOMAKI KUNIO
权利人:HIROSE YOICHI; SHOWA DENKO KK
摘要:A method for vapor-phase synthesis of diamond comprises burning a raw material compound for synthesis of diamond thereby forming a combustion flame, disposing a substrate for deposition of diamond in said combustion flame, and keeping said substrate at a prescribed temperature, thereby inducing deposition of diamond on said substrate.

专利号:US-2016317682-A1
优先权日:2015-04-30
标题:PREPARATION OF Ag18F AND ITS USE IN THE SYNTHESIS OF PET RADIOTRACERS
发明人：SCOTT PETER J H; BROOKS ALLEN F; ICHIISHI NAOKO; SANFORD MELANIE S
权利人:UNIV MICHIGAN REGENTS; THE REGENTS OFTHE UNIV OF MICHIGAN
摘要:Copper-catalyzed radiofluorination of aryl iodides using Ag 18 F, methods of preparing Ag 18 F, and compounds obtained by copper-catalyzed radiofluorination of aryl iodides using Ag 18 F are disclosed. Diagnostic and therapeutic methods involving such compounds also are disclosed.

专利号:US-11745159-B2
优先权日:2017-10-20
标题:Heated nanowells for polynucleotide synthesis
发明人：MARSH EUGENE P; INDERMUHLE PIERRE F; PECK BILL JAMES
权利人:TWIST BIOSCIENCE CORP
摘要:Defined sequence RNA synthesis by 3′→5′ direction is now well established and currently in use for synthesis and development of vast variety of therapeutic grade RNA and Si RNA etc. A number of such synthetic RNA requires a modification or labeling of 3′-end of an oligonucleotide. The synthesis of 3′-end modified RNA requiring lipophilic, long chain ligands or chromophores, using 3′→5′ synthesis methodology is challenging, requires corresponding solid support and generally results in low coupling efficiency and lower purity of the final oligonucleotide in general because of large amount of truncated sequences containing desired hydrophobic modification. We have approached this problem by developing reverse RNA monomer phosphoramidites for RNA synthesis in 5′→3′-direction. They lead to very clean oligonucleotide synthesis allowing for introduction of various modifications at the 3′-end.

专利号:US-7193077-B2
优先权日:2003-08-30
标 题 :Exocyclic amine triaryl methyl protecting groups in two-step polynucleotide synthesis
发明人：DELLINGER DOUGLAS J; SIERZCHALA AGNIESZKA B; CARUTHERS MARVIN H
权利人:AGILENT TECHNOLOGIES INC
摘要:Precursors for use in the synthesis of polynucleotides and methods of using the precursors in synthesizing polynucleotides are disclosed. The precursors include a heterocyclic base having an exocyclic amine group and a substituted or unsubstituted triaryl methyl protecting group bound to the exocyclic amine group.

专利号:US-7427679-B2
优先权日:2003-08-30
标 题:Precursors for two-step polynucleotide synthesis
发明人：DELLINGER DOUGLAS J; SIERZCHALA AGNIESZKA B; CARUTHERS MARVIN H
权利人:AGILENT TECHNOLOGIES INC
摘要:Precursors for use in the synthesis of polynucleotides are disclosed. The precursors include a heterocyclic base having an exocyclic amine group and a substituted or unsubstituted triaryl methyl protecting group bound to the exocyclic amine group. In particular embodiments, the precursor has the structure: n nwherein:n O and H represent oxygen and hydrogen, respectively, R 1 is hydrido, hydroxyl, protected hydroxyl, lower alkyl, modified lower alkyl, or alkoxy, one of R 2 or R 3 is a hydroxyl protecting group; and the other of R 2 or R 3 is a reactive group capable of reacting with a reactive site hydroxyl, Base is a heterocyclic base having an exocyclic amine group, and Tram is a triaryl methyl group having the structure (V) n nwherein the broken line represents a bond to the amino nitrogen of the exocyclic amine group, and R 4 , R 5 and R 6 are independently selected from unsubstituted or substituted aryl groups, provided that at least one of R 4 , R 5 , and R 6 is an aryl group other than phenyl and other than substituted phenyl.

专利号:US-2008312430-A1
优先权日:2004-10-20
标题:Method of Preparing or Synthesizing Polyazamacrocycle Derivatives
发明人：CIHELNIK SIMON; DROZ LADISLAV; SRAMEK MARTIN
权利人:THERAPHARM GMBH
摘要:The present invention relates to novel processes for the synthesis of polyazamacrocycle derivatives. Furthermore, the present invention relates to novel polyazamacrocycle derivatives as well as novel intermediates for the synthesis of said polyazamacrocycle derivatives.