专利号:US-7344863-B2 优先权日:1998-03-13 标题:Methods for producing polypeptides through enhanced synthesis of encoding nucleic acid molecules 发明人:LI WU-BO; JESSEE JOEL A; SCHUSTER DAVID; XIA JIULIN; GEBEYEHU GULILAT 权利人:INVITROGEN CORP 摘要:The present invention is directed to compositions and methods for enhancing synthesis of nucleic acid molecules, particularly GC-rich nucleic acid molecules. Specifically, the invention provides compositions comprising one or more nitrogen-containing organic compounds having a formula selected from the group consisting of formula I and formula II (or salts or derivatives thereof), preferably 4-methylmorpholine N-oxide or betaine (carboxymethyltrimethylammonium), and further comprising one or more compounds selected from the group consisting of proline and an N-alkylimidazole compound, and more preferably proline, 1-methylimidazole or 4-methylimidazole. The invention further relates to methods for enhanced, high-fidelity synthesis of nucleic acid molecules, including via amplification (particularly PCR), reverse transcription, and sequencing methods. The invention also relates to nucleic acid molecules synthesized by these methods, to fragments or derivatives thereof, and to vectors and host cells comprising such nucleic acid molecules, fragments, or derivatives. The invention also relates to kits for synthesizing, amplifying, reverse transcribing or sequencing nucleic acid molecules comprising one or more of the compositions of the invention.
专利号:US-2016115113-A1 优先权日:2014-10-28 标题 :Aerobic Oxidative Esterification of Sugar-Derived 1,4-Disubstituted Benzene for Direct Synthesis of Dimethylterephthalate 发明人:SHIRAMIZU MIKA; LATTNER JAMES R; KANDEL KAPIL 权利人:EXXONMOBIL CHEM PATENTS INC 摘要:This invention relates to a dimethylterephthalate production process comprising reacting substituted furan with ethylene under cycloaddition reaction conditions and in the presence of a cycloaddition catalyst to produce a bicyclic ether, dehydrating the bicyclic ether to produce a substituted phenyl, dissolving said substituted phenyl in methanol, and oxidizing and esterifying the substituted phenyl in the presence of an oxidative esterification catalyst to form dimethylterephthalate. Importantly, the process does not include oxidizing the substituted phenyl to form terephthalic acid.
专利号:US-9994887-B2 优先权日:2009-01-08 标题 :Methods and compositions for improving efficiency of nucleic acids amplification reactions 发明人:GONG XIAO-SONG; SULLIVAN JOHN; FU RONGDIAN; WANG YAN; BURSEY EVAN H; CHENG MAN 权利人:BIO RAD LABORATORIES 摘要:The present invention provides methods and compositions for improving the efficiency of nucleic acid amplification reactions. The invention encompasses hybrid polymerases that show increased processivity over wild type polymerases as well as decreased exonucleases activity. The invention also encompasses methods, compositions and kits for conducting nucleic acid synthesis and amplification reactions in which non-specific amplification of primers is reduced.
专利号:US-10070651-B2 优先权日:2015-10-13 标题 :Synthesis and characterization of antimicrobial non-color forming silver-silica nanocomposite 发明人:SANTRA SWADESHMUKUL; BAZATA JOSHUA J 权利人:UNIV CENTRAL FLORIDA RES FOUND INC 摘要:The present invention relates to, inter alia, a composition, a nanocomposite material, and a method for preparing the nanocomposite material. The nanocomposite material includes: a dielectric-silver nanocomposite material, the dielectric-silver nanocomposite material including a silver nanoparticle having a silver ion, and a dielectric material encapsulating the silver nanoparticle, where the silver ion chelates with a matrix of the dielectric material, and a surface plasmon band absorption of the dielectric-silver nanocomposite material lies outside a range of a visible region.
专利号:RU-2030389-C1 优先权日:1991-06-28 标 题:Method of synthesis of 2,2-bis- [4-(3- methacryloylhydroxy -2-hydroxypropoxy)phenyl] propane used as cross-linking component of composition material
专利号:EP-1756190-B1 优先权日:2004-04-14 标 题:Radically curable resin compositions 发明人:JANSEN JOHAN FRANZ GRADUS ANTO; DRIESSEN MARCO MARCUS MATHEUS; VAN DIJCK MICHAEL ALPHONSUS CO 权利人:DSM IP ASSETS BV 摘要:The present invention relates to resin compositions for radical curing comprising a component (I) containing reactive carbon-carbon unsaturations and a component (II) containing XH-groups, with X not being C or O., which resin compositions (a) are substantially free of photoinitiators; (b.) have an average number of reactive carbon-carbon unsaturations of component (I) equal to or higher than 2; (c) have an average number of XH-groups of component (II) equal to or higher than 2; (d) whereby at least one of the average numbers of (b) and (c) is higher than 2; (e) and at most 5 mol% of the reactive unsaturations is capable of undergoing homopolymerisation; (f) respectively is present in the form of a mono-ene functional alkylene; and (g) the molar ratio of the XH-groups and of the reactive unsaturations is in the range of from 4 : 1 to 1 : 4. ?>The present invention also relates to processes for curing such resin compositions, in particular by cold curing. And finally, the present invention also relates to a new process for the synthesis of Diels-Alder adducts of cyclopentadiene and a resin component containing telechelic carbon-carbon unsaturation. ?>The resin compositions are capable of providing constructive materials with tack-free surfaces by fast, and tunable, radical curing, and without any problems of so-called oxygen inhibition. Suitable applications are in chemical anchoring, roofing, flooring, (re)-lining, SMCs and BMCs.
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