CAS: 102-25-0; 1,3,5-Triethylbenzene

该化合物是一种配有分子式C12H18的对称芳香烃,其结构结构有三种乙基组,在苯环上对称替代,有助于其高热稳定性和低极性,该化合物通常用作有机合成的溶剂,特殊化学制造的前体和高性能燃料配方的组成部分,其对称配置增强了化学的惰性,使之适合需要抗氧化和降解的应用.此外,1,3,5-Tri乙基苯展示非极和中极化合物的有利溶性,便利其在研究和工业过程中的使用.

结构式图片

相似化合物

934-80-5 717-74-8 99-62-7

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

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合成工艺路线路线简述

    1,2,4-三乙苯置于三氯化铝体系中,化学反应生成1,3,5-三乙基苯
    参考文献:The Action Of Aluminum Chloride On Aromatic Hydrocarbons. Iii. The Polyethylbenzenes And Tetramethylbenzenes
    标题:The Action Of Aluminum Chloride On Aromatic Hydrocarbons. Iii. The Polyethylbenzenes And Tetramethylbenzenes
    摘要:
    Doi:10.1021/ja01857A074

    专利信息


    专利号:US-2003162992-A1
    优先权日:2001-12-14
    标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
    发明人:WATANABE KYOICHI A; DU JINFA
    摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.

    专利号:US-6355826-B1
    优先权日:1997-09-17
    标题:Synthesis of stable nitrile oxide compounds
    发明人:PARKER DANE KENTON
    权利人:GOODYEAR TIRE & RUBBER
    摘要:This invention discloses a process for the synthesis of stable aryl nitrile oxides which comprises the sequential steps of (1) halomethylating a halomethyl group onto a substituted aromatic compounds wherein said halomethyl group is halomethylated onto a position that is ortho to at least one of the substituent groups on the substituted aromatic compound; (2) converting the ortho halomethylated-substituted aromatic compound into an ortho-substituted aromatic aldehyde by reacting the ortho halomethylated-substituted aromatic compound with a salt selected from the group consisting of sodium 2-nitropropane and potassium 2-nitropropane in a lower alcohol solvent; (3) converting the ortho-substituted aromatic aldehyde into an ortho-substituted aromatic; and (4) converting the ortho-substituted aromatic oxime into the ortho-substituted aryl nitrile oxide by reacting the ortho-substituted aromatic oxime with an aqueous sodium hypochlorite solution.

    专利号:US-7094943-B2
    优先权日:1998-04-27
    标 题 :Solution phase biopolymer synthesis
    发明人:KOESTER HUBERT; WOERL RALF
    权利人:KOESTER HUBERT; WOERL RALF
    摘要:Multifunctional liquid phase carriers (LPCs) and methods of using LPCs for the preparation of biopolymers are provided. The LPCs are highly symmetrical compounds that possess more than two points of attachment for biopolymer synthesis. The LPCs have the formula Sp(X 1 ) n , where Sp is a highly symmetrical moiety such that all X 1 groups are equivalent. X 1 is a functional group that is suitable for biopolymer synthesis, including OH, SH, NH 2 , COOH and the like. Biopolymers that may be produced using the methods provided include oligonucleotides, peptides, protein nucleic acids (PNAs) and oligosaccharides. Analogs of the biopolymers may also be prepared using the methods.

    专利号:EP-1905753-A1
    优先权日:2006-09-26
    标题:Synthesis method of diamondoid
    发明人:WATANABE KATSUYUKI; WATANABE YASUFUMI
    权利人:FUJIFILM CORP
    摘要:A synthesis method of a diamondoid is characterized in that the diamondoid is synthesized from a diamondoid precursor in the presence of at least one Lewis acid and at least one compound capable of reacting with the Lewis acid to generate an acid.

    专利号:US-7741487-B2
    优先权日:2004-08-26
    标题 :Method for producing quaterrylene-3,4:13, 14-tetracarboxy diimides by direct synthesis
    发明人:KOENEMANN MARTIN; BOEHM ARNO; BIDLINGMAIER HERMANN; RIEGER REINHOLD; BLASCHKA PETER; REICHELT HELMUT; KRIEGER MATTHIAS
    权利人:BASF AG
    摘要:A process for preparing quaterrylene-3,4:13,14-tetracarboximides of the general formula I n nin whichn nR, R′ are each independently hydrogen or optionally substituted C 1 -C 30 -alkyl, C 5 -C 8 -cycloalkyl or aryl or hetaryl;n nwhich comprises reacting a perylene-3,4-dicarboximide of the general formula IIan n nin the presence of a base-stable, high-boiling, organic solvent and of an alkali metal base or alkaline earth metal base, with a perylene-3,4-dicarboximide of the general formula IIbn n nin which X is hydrogen, bromine or chlorine.

    专利号:EP-1953140-A1
    优先权日:2007-01-24
    标 题 :Process for the preparation of ezetimibe and derivatives thereof
    发明人:STIMAC ANTON; MOHAR BARBARA; STEPHAN MICHEL; BEVC MOJCA; ZUPET ROK; GARTNER ANDREJ; KROSELJ VESNA; SMRKOLJ MATEJ
    权利人:KRKA
    摘要:The present invention relates to the method of preparing of ezetimibe and in particular to novel intermediates for its synthesis and an improved process for preparing such intermediates. Said intermediates may be obtained in high yields and purity in a fast and cost efficient manner. The present invention relates to a novel crystalline form of ezetimibe as well.
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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:A Metal‐free Direct Arene C−h Amination
    作者:Tao Wang,Marvin Hoffmann,Andreas Dreuw,Edina Hasagić,Chao Hu,Philipp M. Stein,Sina Witzel,Hongwei Shi,Yangyang Yang,Matthias Rudolph,Fabian Stuck,Frank Rominger,Marion Kerscher,Peter Comba,A. Stephen K. Hashmi |发布日期:2021.6.8
    摘要:The Synthesis Of Aryl Amines Via The Formation Of A C−n Bond Is An Essential Tool For The Preparation Of Functional Materials, Active Pharmaceutical Ingredients And Bioactive Products. Usually, This Chemical Connection Is Only Possible By Transition Metal-Catalyzed Reactions, Photochemistry Or Electrochemistry. Here, We Report A Metal-Free Arene C−h Amination Using Hydroxylamine Derivatives Under Benign

    合成参考文献


    参考文献:10.1021/jm200560r
    摘要:Lozano V, Aguado L, Hoorelbeke B, Renders M, Camarasa MJ, Schols D, Balzarini J, San-Félix A, Pérez-Pérez MJ. Targeting HIV entry through interaction with envelope glycoprotein 120 (gp120): synthesis and antiviral evaluation of 1,3,5-triazines with aromatic amino acids. J Med Chem. 2011 Aug 11;54(15):5335–48. doi: 10.1021/jm200560r.
    参考文献:10.1107/s1600536811009639
    摘要:Takahashi H. 4-Chloro-2',4',6'-triethyl-benzophenone: a redetermination. Acta Crystallogr Sect E Struct Rep Online. 2011 Apr 01;67(Pt 4):o935.
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